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Author Details

Andrew W Nicholls
1994
43
24
PMIDPaper TitleJournal TitlePublished Year
34021280REMBI: Recommended Metadata for Biological Images-enabling reuse of microscopy data in biology.Nat Methods2021
33396723Decrease in Myelin-Associated Lipids Precedes Neuronal Loss and Glial Activation in the CNS of the Sandhoff Mouse as Determined by Metabolomics.Metabolites2020
32061126Metabolism and Effects on Endogenous Metabolism of Paracetamol (Acetaminophen) in a Porcine Model of Liver Failure.Toxicological Sciences2020
32343149The analysis of acetaminophen (paracetamol) and seven metabolites in rat, pig and human plasma by U(H)PLC-MS.Bioanalysis2020
30126316Monic acid A: a biomarker in clinical intra-nasal mupirocin medication for MRSA decolonisation.Biomarkers2019
28377426Alterations in endo-lysosomal function induce similar hepatic lipid profiles in rodent models of drug-induced phospholipidosis and Sandhoff disease.J Lipid Res2017
26654758PPAR-pan activation induces hepatic oxidative stress and lipidomic remodelling.Free Radic Biol Med2016
27331087Metabolomics dataset of PPAR-pan treated rat liver.Data Brief2016
26464084Systems toxicology: modelling biomarkers of glutathione homeostasis and paracetamol metabolism.Drug Discovery Today: Technologies2015
25598764Molecular phenotyping of a UK population: defining the human serum metabolome.Metabolomics2015
24586186Genome-wide association study of metabolic traits reveals novel gene-metabolite-disease links.PLoS Genet2014
24988476Novel gut-based pharmacology of metformin in patients with type 2 diabetes mellitus.PLoS One2014
23046260Realising the potential of metabolomics.Bioanalysis2012
23046267The importance of experimental design and QC samples in large-scale and MS-driven untargeted metabolomic studies of humans.Bioanalysis2012
22069722H NMR spectroscopy-based metabolomic assessment of uremic toxicity, with toxicological outcomes, in male rats following an acute, mid-life insult from ochratoxin a.Toxins2011
21720319Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry.Nat Protoc2011
21843327The contrasting roles of PPARδ and PPARγ in regulating the metabolic switch between oxidation and storage of fats in white adipose tissue.Genome Biol2011
22069742Comparative (1)H NMR metabolomic urinalysis of people diagnosed with Balkan endemic nephropathy, and healthy subjects, in Romania and Bulgaria: a pilot study.Toxins2011
19968882Increased hepatic oxidative metabolism distinguishes the action of Peroxisome proliferator-activated receptor delta from Peroxisome proliferator-activated receptor gamma in the ob/ob mouse.Genome Med2009
19602617Metabolic phenotyping of a model of adipocyte differentiation.Physiol Genomics2009
24039616Proposed minimum reporting standards for chemical analysis Chemical Analysis Working Group (CAWG) Metabolomics Standards Initiative (MSI).Metabolomics2007
16675996Personalized medicine progresses.Nature Medicine2006
16864507Identification of phenacetin metabolites in human urine after administration of phenacetin-C2H3: measurement of futile metabolic deacetylation via HPLC/MS-SPE-NMR and HPLC-ToF MS.Xenobiotica2006
17054419Metabolomics as a functional genomic tool for understanding lipid dysfunction in diabetes, obesity and related disorders.Pharmacogenomics2006
15808519Comparative metabonomics of differential hydrazine toxicity in the rat and mouse.Toxicology and Applied Pharmacology2005
15720114Integrated metabonomic analysis of the multiorgan effects of hydrazine toxicity in the rat.Chemical Research in Toxicology2005
14967004Use of metabonomics to identify impaired fatty acid metabolism as the mechanism of a drug-induced toxicity.Chemical Research in Toxicology2004
15388097Automatic alignment of individual peaks in large high-resolution spectral data sets.Journal of Magnetic Resonance2004
14615964NMR spectroscopic-based metabonomic studies of urinary metabolite variation in acclimatizing germ-free rats.Chemical Research in Toxicology2003
12081031Metabolic profiling of rodent biological fluids via 1H NMR spectroscopy using a 1 mm microlitre probe.Analyst2002
11511171Metabonomic investigations into hydrazine toxicity in the rat.Chemical Research in Toxicology2001
10858320Chemometric models for toxicity classification based on NMR spectra of biofluids.Chemical Research in Toxicology2000
10746955Directly-coupled HPLC-NMR spectroscopic studies of metabolism and futile deacetylation of phenacetin in the rat.Journal of Pharmaceutical and Biomedical Analysis1999
9548796Nuclear magnetic resonance spectroscopic and principal components analysis investigations into biochemical effects of three model hepatotoxins.Chemical Research in Toxicology1998
9719578Development of a model for classification of toxin-induced lesions using 1H NMR spectroscopy of urine combined with pattern recognition.NMR in Biomedicine1998
9413921NMR spectroscopic studies on the metabolism and futile deacetylation of phenacetin in the rat.Xenobiotica1997
9256115Direct observation of resolved intracellular and extracellular water signals in intact human red blood cells using 1H MAS NMR spectroscopy.Magnetic Resonance in Medicine1997
9160256NMR and HPLC-NMR spectroscopic studies of futile deacetylation in paracetamol metabolites in rat and man.Journal of Pharmaceutical and Biomedical Analysis1997
8930759Development of a simple liquid chromatographic method for the separation of mixtures of positional isomers and anomers of synthetic 2-, 3- and 4-fluorobenzoic acid glucuronides formed via acyl migration reactions.1996
8951247NMR spectroscopic and theoretical chemistry studies on the internal acyl migration reactions of the 1-O-acyl-beta-D-glucopyranuronate conjugates of 2-, 3-, and 4-(trifluoromethyl) benzoic acids.Chemical Research in Toxicology1996
8580156Assignment of the 750 MHz 1H NMR resonances from a mixture of transacylated ester glucuronic acid conjugates with the aid of oversampling and digital filtering during acquisition.Journal of Pharmaceutical and Biomedical Analysis1995
7748197High resolution NMR spectroscopic studies on the metabolism and futile deacetylation of 4-hydroxyacetanilide (paracetamol) in the rat.Biochemical Pharmacology1995
7810870High-field deuterium nuclear magnetic resonance spectroscopic monitoring of the pharmacokinetics of selectively deuterated benzoic acid in man.Analytical Biochemistry1994
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