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Author Details

Laura Adrienne Cupples
1983
709
141
PMIDPaper TitleJournal TitlePublished Year
37009668The impact of obesity on lung function measurements and respiratory disease: A Mendelian randomization study.2023
37756531Clonal Hematopoiesis of Indeterminate Potential (CHIP) and Incident Type 2 Diabetes Risk.Diabetes Care2023
37662265WHOLE GENOME SEQUENCING ANALYSIS OF BODY MASS INDEX IDENTIFIES NOVEL AFRICAN ANCESTRY-SPECIFIC RISK ALLELE.medRxiv2023
37770635Multi-ancestry genome-wide study identifies effector genes and druggable pathways for coronary artery calcification.Nat Genet2023
35069183The Pharmacogenetics of Statin Therapy on Clinical Events: No Evidence that Genetic Variation Affects Statin Response on Myocardial Infarction.Front Pharmacol2022
35396452Meta-analysis of genome-wide association studies identifies ancestry-specific associations underlying circulating total tau levels.Commun Biol2022
35385699Polygenic transcriptome risk scores for COPD and lung function improve cross-ethnic portability of prediction in the NHLBI TOPMed program.Am J Hum Genet2022
35385311Mendelian randomization supports bidirectional causality between telomere length and clonal hematopoiesis of indeterminate potential.Sci Adv2022
36220816Whole genome sequence analysis of blood lipid levels in >66,000 individuals.Nat Commun2022
35501457Lymphocyte activation gene-3-associated protein networks are associated with HDL-cholesterol and mortality in the Trans-omics for Precision Medicine program.Commun Biol2022
35927319Rare genetic variants explain missing heritability in smoking.Nat Hum Behav2022
36119389Recommendations on the use and reporting of race, ethnicity, and ancestry in genetic research: Experiences from the NHLBI TOPMed program.Cell Genom2022
36568030Whole-exome sequence analysis of anthropometric traits illustrates challenges in identifying effects of rare genetic variants.HGG Adv2022
34855941Association of clonal hematopoiesis with chronic obstructive pulmonary disease.Blood2022
34536413Multiethnic genome-wide and HLA association study of total serum IgE level.J Allergy Clin Immunol2021
33964857Genetic variants modify the associations of concentrations of methylmalonic acid, vitamin B-12, vitamin B-6, and folate with bone mineral density.Am J Clin Nutr2021
33586462Small Dense Low-Density Lipoprotein Cholesterol Is the Most Atherogenic Lipoprotein Parameter in the Prospective Framingham Offspring Study.Journal of the American Heart Association2021
34167169Exome sequence association study of levels and longitudinal change of cardiovascular risk factor phenotypes in European Americans and African Americans from the Atherosclerosis Risk in Communities Study.Genet Epidemiol2021
33846329Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices.Nat Commun2021
34214102Identification of novel and rare variants associated with handgrip strength using whole genome sequence data from the NHLBI Trans-Omics in Precision Medicine (TOPMed) Program.PLoS One2021
33568059Revisiting methods for modeling longitudinal and survival data: Framingham Heart Study.BMC Medical Research Methodology2021
33720349Robust, flexible, and scalable tests for Hardy-Weinberg equilibrium across diverse ancestries.Genetics2021
33713608Discovery and fine-mapping of height loci via high-density imputation of GWASs in individuals of African ancestry.Am J Hum Genet2021
33500576Lifestyle Risk Score: handling missingness of individual lifestyle components in meta-analysis of gene-by-lifestyle interactions.Eur J Hum Genet2021
34337551BinomiRare: A robust test for association of a rare genetic variant with a binary outcome for mixed models and any case-control proportion.HGG Adv2021
34302344ANNORE: genetic fine-mapping with functional annotation.Hum Mol Genet2021
33372532Proteomic Signatures of Lifestyle Risk Factors for Cardiovascular Disease: A Cross-Sectional Analysis of the Plasma Proteome in the Framingham Heart Study.J Am Heart Assoc2021
33418499Whole genome sequence analyses of eGFR in 23,732 people representing multiple ancestries in the NHLBI trans-omics for precision medicine (TOPMed) consortium.EBioMedicine2021
35036986Association of mitochondrial DNA copy number with cardiometabolic diseases.Cell Genom2021
34446064Whole-genome association analyses of sleep-disordered breathing phenotypes in the NHLBI TOPMed program.Genome Med2021
33057025Whole genome sequence analysis of pulmonary function and COPD in 19,996 multi-ethnic participants.Nat Commun2020
32211507Disclosing genetic risk for Alzheimer's dementia to individuals with mild cognitive impairment.Alzheimers Dement (N Y)2020
33339817Loss-of-function genomic variants highlight potential therapeutic targets for cardiovascular disease.Nat Commun2020
32510982Role of Rare and Low-Frequency Variants in Gene-Alcohol Interactions on Plasma Lipid Levels.Circ Genom Precis Med2020
31127295A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure.Hum Mol Genet2019
31719535Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration.Nat Commun2019
31564435Impact of Rare and Common Genetic Variants on Diabetes Diagnosis by Hemoglobin A1c in Multi-Ancestry Cohorts: The Trans-Omics for Precision Medicine Program.Am J Hum Genet2019
31869403Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations.PLoS Genet2019
33311841GENERATING SURVIVAL TIMES WITH TIME-VARYING COVARIATES USING THE LAMBERT W FUNCTION.Communications in Statistics Part B: Simulation and Computation2019
30232418Integrating genetic, transcriptional, and biological information provides insights into obesity.Int J Obes (Lond)2019
29857119Quality control and integration of genotypes from two calling pipelines for whole genome sequence data in the Alzheimer's disease sequencing project.Genomics2019
29988085Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium.Mol Psychiatry2019
30653739A fully adjusted two-stage procedure for rank-normalization in genetic association studies.Genet Epidemiol2019
29688268A Longitudinal Study of Trunk Muscle Properties and Severity of Thoracic Kyphosis in Women and Men: The Framingham Study.J Gerontol A Biol Sci Med Sci2019
30820047Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.Nat Genet2019
30755687Revisit Population-based and Family-based Genotype Imputation.Scientific Reports2019
27958378Large-scale pharmacogenomic study of sulfonylureas and the QT, JT and QRS intervals: CHARGE Pharmacogenomics Working Group.Pharmacogenomics J2018
28726810A randomized controlled trial of disclosing genetic risk information for Alzheimer disease via telephone.Genet Med2018
28941034Genome-Wide Interactions with Dairy Intake for Body Mass Index in Adults of European Descent.Mol Nutr Food Res2018
28719597Pharmacogenomics study of thiazide diuretics and QT interval in multi-ethnic populations: the cohorts for heart and aging research in genomic epidemiology.Pharmacogenomics J2018
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