| 36893255 | Protein-metabolite interactomics of carbohydrate metabolism reveal regulation of lactate dehydrogenase. | Science | 2023 |
| 37678706 | The Cytotoxic Mycobacteriophage Protein Phaedrus gp82 Interacts with and Modulates the Activity of the Host ATPase, MoxR. | J Mol Biol | 2023 |
| 37327313 | Discovering selective antiferroptotic inhibitors of the 15LOX/PEBP1 complex noninterfering with biosynthesis of lipid mediators. | Proc Natl Acad Sci U S A | 2023 |
| 35315486 | Itavastatin and resveratrol increase triosephosphate isomerase protein in a newly identified variant of TPI deficiency. | Dis Model Mech | 2022 |
| 36379252 | On the illusion of auxotrophy: met15ο yeast cells can grow on inorganic sulfur, thanks to the previously uncharacterized homocysteine synthase Yll058w. | J Biol Chem | 2022 |
| 35101798 | Inactivation of RIP3 kinase sensitizes to 15LOX/PEBP1-mediated ferroptotic death. | Redox Biol | 2022 |
| 33126055 | Resolving the paradox of ferroptotic cell death: Ferrostatin-1 binds to 15LOX/PEBP1 complex, suppresses generation of peroxidized ETE-PE, and protects against ferroptosis. | Redox Biol | 2021 |
| 32513718 | PEBP1 acts as a rheostat between prosurvival autophagy and ferroptotic death in asthmatic epithelial cells. | Proc Natl Acad Sci U S A | 2020 |
| 32274853 | Structural and functional divergence of GDAP1 from the glutathione S-transferase superfamily. | FASEB J | 2020 |
| 31075491 | Missense variant in TPI1 (Arg189Gln) causes neurologic deficits through structural changes in the triosephosphate isomerase catalytic site and reduced enzyme levels in vivo. | Biochim Biophys Acta Mol Basis Dis | 2019 |
| 31383866 | The Rad51 paralogs facilitate a novel DNA strand specific damage tolerance pathway. | Nat Commun | 2019 |
| 30762363 | Characterization of Differential Dynamics, Specificity, and Allostery of Lipoxygenase Family Members. | J Chem Inf Model | 2019 |
| 30525572 | Empowerment of 15-Lipoxygenase Catalytic Competence in Selective Oxidation of Membrane ETE-PE to Ferroptotic Death Signals, HpETE-PE. | J Am Chem Soc | 2018 |
| 29053969 | PEBP1 Wardens Ferroptosis by Enabling Lipoxygenase Generation of Lipid Death Signals. | Cell | 2017 |
| 28117766 | Combining Wet and Dry Lab Techniques to Guide the Crystallization of Large Coiled-coil Containing Proteins. | J Vis Exp | 2017 |
| 27031109 | Structural and Genetic Studies Demonstrate Neurologic Dysfunction in Triosephosphate Isomerase Deficiency Is Associated with Impaired Synaptic Vesicle Dynamics. | PLoS Genet | 2016 |
| 27758857 | Structure of the Shroom-Rho Kinase Complex Reveals a Binding Interface with Monomeric Shroom That Regulates Cell Morphology and Stimulates Kinase Activity. | J Biol Chem | 2016 |
| 27840029 | The Histone Modification Domain of Paf1 Complex Subunit Rtf1 Directly Stimulates H2B Ubiquitylation through an Interaction with Rad6. | Mol Cell | 2016 |
| 25463631 | Triosephosphate isomerase I170V alters catalytic site, enhances stability and induces pathology in a Drosophila model of TPI deficiency. | Biochim Biophys Acta | 2015 |
| 26215801 | Promotion of presynaptic filament assembly by the ensemble of S. cerevisiae Rad51 paralogues with Rad52. | Nat Commun | 2015 |
| 24161951 | Cross-talk between diverse serine integrases. | J Mol Biol | 2014 |
| 25171888 | The interaction between Shroom3 and Rho-kinase is required for neural tube morphogenesis in mice. | Biol Open | 2014 |
| 24112940 | The structure of Xis reveals the basis for filament formation and insight into DNA bending within a mycobacteriophage intasome. | J Mol Biol | 2014 |
| 23460207 | The Shu complex interacts with Rad51 through the Rad51 paralogues Rad55-Rad57 to mediate error-free recombination. | Nucleic Acids Res | 2013 |
| 24349032 | Structure of a highly conserved domain of Rock1 required for Shroom-mediated regulation of cell morphology. | PLoS One | 2013 |
| 24101474 | Structural basis for Spt5-mediated recruitment of the Paf1 complex to chromatin. | Proc Natl Acad Sci U S A | 2013 |
| 23641070 | Evidence of a triosephosphate isomerase non-catalytic function crucial to behavior and longevity. | J Cell Sci | 2013 |
| 22318720 | Cdc73 subunit of Paf1 complex contains C-terminal Ras-like domain that promotes association of Paf1 complex with chromatin. | J Biol Chem | 2012 |
| 22950046 | A novel Drosophila SOD2 mutant demonstrates a role for mitochondrial ROS in neurodevelopment and disease. | Brain Behav | 2012 |
| 22493320 | Structure of Shroom domain 2 reveals a three-segmented coiled-coil required for dimerization, Rock binding, and apical constriction. | Mol Biol Cell | 2012 |
| 20352123 | Dissection of structure and function of the N-terminal domain of mouse DNMT1 using regional frame-shift mutagenesis. | PLoS One | 2010 |
| 18089575 | Structural and functional analysis of the Spt16p N-terminal domain reveals overlapping roles of yFACT subunits. | J Biol Chem | 2008 |
| 17803945 | Autoregulation of the rsc4 tandem bromodomain by gcn5 acetylation. | Mol Cell | 2007 |
| 17942675 | Potent D-peptide inhibitors of HIV-1 entry. | Proc Natl Acad Sci U S A | 2007 |
| 16678108 | The structure of the yFACT Pob3-M domain, its interaction with the DNA replication factor RPA, and a potential role in nucleosome deposition. | Mol Cell | 2006 |
| 15721250 | E1 on the move. | Mol Cell | 2005 |
| 16141067 | Inositol hexakisphosphate is bound in the ADAR2 core and required for RNA editing. | Science | 2005 |
| 15452557 | Grabbing E2 by the tail. | Nat Struct Mol Biol | 2004 |
| 12660720 | Two-stepping with E1. | Nat Struct Biol | 2003 |
| 12005425 | SUMO wrestling with specificity. | Structure | 2002 |
| 12504688 | Structural basis of ubiquitylation. | Curr Opin Struct Biol | 2002 |
| 11440714 | Molecular insights into polyubiquitin chain assembly: crystal structure of the Mms2/Ubc13 heterodimer. | Cell | 2001 |
| 10722750 | Characterization of the N-terminal domain of the yeast transcriptional repressor Tup1. Proposal for an association model of the repressor complex Tup1 x Ssn6. | J Biol Chem | 2000 |
| 11062549 | Opening doors into the proteasome. | Nat Struct Biol | 2000 |