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Author Details

Vincenzo De Filippis
Department of Pharmaceutical and Pharmacological Sciences, University of Padua
1990
96
29
PMIDPaper TitleJournal TitlePublished Year
35052783NOG-Derived Peptides Can Restore Neuritogenesis on a CRASH Syndrome Cell Model.Biomedicines2022
35701444Exogenous human α-Synuclein acts in vitro as a mild platelet antiaggregant inhibiting α-thrombin-induced platelet activation.Sci Rep2022
36614141The Role of Proteolysis in Amyloidosis.Int J Mol Sci2022
34712402A conserved Neurite Outgrowth and Guidance motif with biomimetic potential in neuronal Cell Adhesion Molecules.Comput Struct Biotechnol J2021
33920144Von Willebrand Factor Multimers and the Relaxation Response: A One-Year Study.Entropy (Basel)2021
33727531Mapping specificity, cleavage entropy, allosteric changes and substrates of blood proteases in a high-throughput screen.Nat Commun2021
33805987Interaction of Lactoferrin with Unsaturated Fatty Acids: In Vitro and In Vivo Study of Human Lactoferrin/Oleic Acid Complex Cytotoxicity.Materials (Basel)2021
33803867Sperm Cholesterol Content Modifies Sperm Function and TRPV1-Mediated Sperm Migration.Int J Mol Sci2021
33633702A Novel Aza-Derivative Inhibits <i>agr</i> Quorum Sensing Signaling and Synergizes Methicillin-Resistant <i>Staphylococcus aureus</i> to Clindamycin.Front Microbiol2021
34815454Staphylococcus aureus iron-regulated surface determinant B (IsdB) protein interacts with von Willebrand factor and promotes adherence to endothelial cells.Sci Rep2021
32518155The J-elongated conformation of β<sub>2</sub>-glycoprotein I predominates in solution: implications for our understanding of antiphospholipid syndrome.J Biol Chem2020
33033332Endocrine disruption of vitamin D activity by perfluoro-octanoic acid (PFOA).Sci Rep2020
33311636A serine protease secreted from Bacillus subtilis cleaves human plasma transthyretin to generate an amyloidogenic fragment.Commun Biol2020
32149259Application of Circular Dichroism and Fluorescence Spectroscopies To Assess Photostability of Water-Soluble Porcine Lens Proteins.ACS Omega2020
30622139Fibronectin-binding protein B (FnBPB) from <i>Staphylococcus aureus</i> protects against the antimicrobial activity of histones.J Biol Chem2019
31857654SHBG141-161 Domain-Peptide Stimulates GPRC6A-Mediated Response in Leydig and β-Langerhans cell lines.Sci Rep2019
30670733Effects of point mutations in the binding pocket of the mouse major urinary protein MUP20 on ligand affinity and specificity.Sci Rep2019
29230873Noncoded amino acids in protein engineering: Structure-activity relationship studies of hirudin-thrombin interaction.Biotechnol Appl Biochem2018
30466070Lupus anticoagulant identifies two distinct groups of patients with different antibody patterns.Thromb Res2018
29378089Impaired sperm function in infertile men relies on the membrane sterol pattern.Andrology2018
28684417Non-canonical proteolytic activation of human prothrombin by subtilisin from <i>Bacillus subtilis</i> may shift the procoagulant-anticoagulant equilibrium toward thrombosis.J Biol Chem2017
28187222Impaired Release of Vitamin D in Dysfunctional Adipose Tissue: New Cues on Vitamin D Supplementation in Obesity.J Clin Endocrinol Metab2017
28151647Single-Cell and Single-Molecule Analysis Unravels the Multifunctionality of the Staphylococcus aureus Collagen-Binding Protein Cna.ACS Nano2017
28490758Identifying conformational changes with site-directed spin labeling reveals that the GTPase domain of HydF is a molecular switch.Sci Rep2017
27246559Neuronal commitment of human circulating multipotent cells by carbon nanotube-polymer scaffolds and biomimetic peptides.Nanomedicine (Lond)2016
27673554Osteocalcin and Sex Hormone Binding Globulin Compete on a Specific Binding Site of GPRC6A.Endocrinology2016
27818145A MICU1 Splice Variant Confers High Sensitivity to the Mitochondrial Ca<sup>2+</sup> Uptake Machinery of Skeletal Muscle.Mol Cell2016
27760842Molecular mapping of α-thrombin (αT)/β2-glycoprotein I (β2GpI) interaction reveals how β2GpI affects αT functions.Biochem J2016
27347732Loop Electrostatics Asymmetry Modulates the Preexisting Conformational Equilibrium in Thrombin.Biochemistry2016
25546847Enhanced neuronal cell differentiation combining biomimetic peptides and a carbon nanotube-polymer scaffold.Nanomedicine2015
26001728Thrombin inhibits the anti-myeloperoxidase and ferroxidase functions of ceruloplasmin: relevance in rheumatoid arthritis.Free Radic Biol Med2015
24896339Carboxylation-dependent conformational changes of human osteocalcin.Front Biosci (Landmark Ed)2014
25093461Uncarboxylated osteocalcin stimulates 25-hydroxy vitamin D production in Leydig cell line through a GPRC6a-dependent pathway.Endocrinology2014
23578283β2 -Glycoprotein I binds to thrombin and selectively inhibits the enzyme procoagulant functions.J Thromb Haemost2013
21937160Modeling ADAMTS13-von Willebrand factor interaction: Implications for oxidative stress-related cardiovascular diseases and type 2A von Willebrand disease.Biophys Chem2012
22635233Circulating β2 glycoprotein I-IgG anti-β2 glycoprotein I immunocomplexes in patients with definite antiphospholipid syndrome.Lupus2012
22091998Oxidation of Met1606 in von Willebrand factor is a risk factor for thrombotic and septic complications in chronic renal failure.Biochem J2012
21605335Oxidized von Willebrand factor is efficiently cleaved by serine proteases from primary granules of leukocytes: divergence from ADAMTS-13.J Thromb Haemost2011
21834793A novel protein from the serum of Python sebae, structurally homologous with type-γ phospholipase A(2) inhibitor, displays antitumour activity.Biochem J2011
21771635RNase A oligomerization through 3D domain swapping is favoured by a residue located far from the swapping domains.Biochimie2011
21620443Antibodies to Domain I of β(2)Glycoprotein I are in close relation to patients risk categories in Antiphospholipid Syndrome (APS).Thromb Res2011
19969076Formation of methionine sulfoxide by peroxynitrite at position 1606 of von Willebrand factor inhibits its cleavage by ADAMTS-13: A new prothrombotic mechanism in diseases associated with oxidative stress.Free Radic Biol Med2010
20889971Thrombin inhibition by serpins disrupts exosite II.J Biol Chem2010
20440842Chemical synthesis and characterization of wild-type and biotinylated N-terminal domain 1-64 of beta2-glycoprotein I.Protein Sci2010
20081094A novel role for iron in modulating the activity and membrane-binding ability of a trimmed soybean lipoxygenase-1.FASEB J2010
19167525Conformational and biochemical characterization of a biologically active rat recombinant Protease Nexin-1 expressed in E. coli.Biochim Biophys Acta2009
19860834Unusual stability of human neuroglobin at low pH--molecular mechanisms and biological significance.FEBS J2009
18399795Catecholaminergic polymorphic ventricular tachycardia-related mutations R33Q and L167H alter calcium sensitivity of human cardiac calsequestrin.Biochem J2008
18779330Fibrinogen-elongated gamma chain inhibits thrombin-induced platelet response, hindering the interaction with different receptors.J Biol Chem2008
17567746o-Nitrotyrosine and p-iodophenylalanine as spectroscopic probes for structural characterization of SH3 complexes.Protein Sci2007
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Collaborators

Laura Acquasaliente
Department of Pharmaceutical and Pharmacological Sciences, University of Padova
Co-authored papers 19
Paola Picotti
Institute of Molecular Systems Biology, ETH Zurich
Co-authored papers 2
Federico Uliana
Institute of Biochemistry, ETH Zurich
Co-authored papers 2
Roberto Vettor
University Hospital of Padova
Co-authored papers 2
Pier Mannuccio Mannucci
Co-authored papers 2
Flora Peyvandi
Co-authored papers 2
Ruedi Aebersold
Institute of Molecular Systems Biology, ETH Zurich
Co-authored papers 1
Rodolfo Ciuffa
Institute of Molecular Systems Biology, ETH Zurich
Co-authored papers 1
Chris Sander
Broad Institute of MIT and Harvard
Co-authored papers 1
Bernd Wollscheid
ETH Zurich
Co-authored papers 1
Ulrich Auf dem Keller
Technical University of Denmark
Co-authored papers 1
Sandra Goetze
ETH Zurich
Co-authored papers 1
Matej Vizovi??ek
Jozef Stefan Institute
Co-authored papers 1
Dmitri I Svergun
King's College London BHF Centre for Research Excellence
Co-authored papers 1
Patrice Vachette
Universite Paris-Saclay, CNRS, Institute for Integrative Biology of the Cell (I2BC)
Co-authored papers 1
Rosario Rizzuto
Co-authored papers 1
Giorgio Colombo
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
Co-authored papers 1
Andrea Fossati
J. David Gladstone Institutes
Co-authored papers 1
Fabian Frommelt
CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
Co-authored papers 1
Rino Rappuoli
Co-authored papers 1
Giovanni Gambaro
Co-authored papers 1
Martino Bolognesi
University of Milano
Co-authored papers 1
Matthias Gstaiger
Institute of Molecular Systems Biology, ETH Zurich
Co-authored papers 1
Release 1.2