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Author Details

William D Martin
EpiVax Inc.
2001
103
31
PMIDPaper TitleJournal TitlePublished Year
37666923Optimization of therapeutic antibodies for reduced self-association and non-specific binding via interpretable machine learning.Nat Biomed Eng2024
37931868Development of IFNβ-1a versions with reduced immunogenicity and full in vitro biological activity for the treatment of multiple sclerosis.Clin Immunol2023
38022550Does human homology reduce the potential immunogenicity of non-antibody scaffolds?Front Immunol2023
37697150Immunoinformatic Risk Assessment of Host Cell Proteins During Process Development for Biologic Therapeutics.AAPS J2023
34882038Neoantigen-based personalized cancer vaccines: the emergence of precision cancer immunotherapy.Expert Rev Vaccines2022
36945694<i>In silico</i> Immunogenicity Assessment for Sequences Containing Unnatural Amino Acids: A Method Using Existing <i>in silico</i> Algorithm Infrastructure and a Vision for Future Enhancements.Front Drug Discov (Lausanne)2022
33412295Identification of a potent regulatory T cell epitope in factor V that modulates CD4+ and CD8+ memory T cell responses.Clin Immunol2021
34798238Development of highly stable and de-immunized versions of recombinant alpha interferon: Promising candidates for the treatment of chronic and emerging viral diseases.Clin Immunol2021
34220802Immune Tolerance-Adjusted Personalized Immunogenicity Prediction for Pompe Disease.Front Immunol2021
34168657Bridging Computational Vaccinology and Vaccine Development Through Systematic Identification, Characterization, and Downselection of Conserved and Variable Circumsporozoite Protein CD4 T Cell Epitopes From Diverse <i>Plasmodium falciparum</i> Strains.Front Immunol2021
33976291Multi-step screening of neoantigens' HLA- and TCR-interfaces improves prediction of survival.Sci Rep2021
34025684Identification, Selection and Immune Assessment of Liver Stage CD8 T Cell Epitopes From <i>Plasmodium falciparum</i>.Front Immunol2021
34305923Identification and Immune Assessment of T Cell Epitopes in Five <i>Plasmodium falciparum</i> Blood Stage Antigens to Facilitate Vaccine Candidate Selection and Optimization.Front Immunol2021
30614773Immune escape and immune camouflage may reduce the efficacy of RTS,S vaccine in Malawi.Hum Vaccin Immunother2020
31951773<i>In silico</i> identification and modification of T cell epitopes in pertussis antigens associated with tolerance.Hum Vaccin Immunother2020
33123135New Immunoinformatics Tools for Swine: Designing Epitope-Driven Vaccines, Predicting Vaccine Efficacy, and Making Vaccines on Demand.Front Immunol2020
32962468Exploit T cell Immunity for Rapid, Safe and Effective COVID-19 Vaccines.Expert Rev Vaccines2020
32278900T cell epitope content comparison (EpiCC) analysis demonstrates a bivalent PCV2 vaccine has greater T cell epitope overlap with field strains than monovalent PCV2 vaccines.Vet Immunol Immunopathol2020
32318055Better Epitope Discovery, Precision Immune Engineering, and Accelerated Vaccine Design Using Immunoinformatics Tools.Front Immunol2020
31629569Differential functional patterns of memory CD4<sup>+</sup> and CD8<sup>+</sup> T-cells from volunteers immunized with Ty21a typhoid vaccine observed using a recombinant Escherichia coli system expressing S. Typhi proteins.Vaccine2020
30828331Promiscuous <i>Coxiella burnetii</i> CD4 Epitope Clusters Associated With Human Recall Responses Are Candidates for a Novel T-Cell Targeted Multi-Epitope Q Fever Vaccine.Front Immunol2019
31695065Therapeutic administration of Tregitope-Human Albumin Fusion with Insulin Peptides to promote Antigen-Specific Adaptive Tolerance Induction.Sci Rep2019
31594990Publisher Correction: A humanized mouse model identifies key amino acids for low immunogenicity of H7N9 vaccines.Sci Rep2019
31331958Coxiella burnetii Epitope-Specific T-Cell Responses in Patients with Chronic Q Fever.Infect Immun2019
31331771Highly conserved influenza T cell epitopes induce broadly protective immunity.Vaccine2019
30015562T cell epitope engineering: an avian H7N9 influenza vaccine strategy for pandemic preparedness and response.Hum Vaccin Immunother2018
28575582An immunoinformatics-derived DNA vaccine encoding human class II T cell epitopes of Ebola virus, Sudan virus, and Venezuelan equine encephalitis virus is immunogenic in HLA transgenic mice.Hum Vaccin Immunother2017
28089609De-immunized and Functional Therapeutic (DeFT) versions of a long lasting recombinant alpha interferon for antiviral therapy.Clin Immunol2017
28455520A humanized mouse model identifies key amino acids for low immunogenicity of H7N9 vaccines.Sci Rep2017
29054116T-cell epitope content comparison (EpiCC) of swine H1 influenza A virus hemagglutinin.Influenza Other Respir Viruses2017
27411061In Vivo Validation of Predicted and Conserved T Cell Epitopes in a Swine Influenza Model.PLoS One2016
26588466T cell epitope redundancy: cross-conservation of the TCR face between pathogens and self and its implications for vaccines and autoimmunity.Expert Rev Vaccines2016
27389971Agility in adversity: Vaccines on Demand.Expert Rev Vaccines2016
25157982HCV epitope, homologous to multiple human protein sequences, induces a regulatory T cell response in infected patients.J Hepatol2015
26370412Development and validation of an epitope prediction tool for swine (PigMatrix) based on the pocket profile method.BMC Bioinformatics2015
26107442An immunoinformatic approach for identification of Trypanosoma cruzi HLA-A2-restricted CD8(+) T cell epitopes.Hum Vaccin Immunother2015
26090577H7N9 T-cell epitopes that mimic human sequences are less immunogenic and may induce Treg-mediated tolerance.Hum Vaccin Immunother2015
25629522Aspartate-β-hydroxylase induces epitope-specific T cell responses in hepatocellular carcinoma.Vaccine2015
25385064C3d adjuvant effects are mediated through the activation of C3d-specific autoreactive T cells.Immunol Cell Biol2015
24721533Peptide-pulsed dendritic cells induce the hepatitis C viral epitope-specific responses of naïve human T cells.Vaccine2014
25483703Immune camouflage: relevance to vaccines and human immunology.Hum Vaccin Immunother2014
25483693VaxCelerate II: rapid development of a self-assembling vaccine for Lassa fever.Hum Vaccin Immunother2014
25454619Tregitope: Immunomodulation powerhouse.Hum Immunol2014
25517089Partial pathogen protection by tick-bite sensitization and epitope recognition in peptide-immunized HLA DR3 transgenic mice.Hum Vaccin Immunother2014
25339942Smarter vaccine design will circumvent regulatory T cell-mediated evasion in chronic HIV and HCV infection.Front Microbiol2014
25111185Dendritic cell-mediated, DNA-based vaccination against hepatitis C induces the multi-epitope-specific response of humanized, HLA transgenic mice.PLoS One2014
25104221Integrated assessment of predicted MHC binding and cross-conservation with self reveals patterns of viral camouflage.BMC Bioinformatics2014
24740005Human immune responses to H. pylori HLA Class II epitopes identified by immunoinformatic methods.PLoS One2014
24888712CHOPPI: a web tool for the analysis of immunogenicity risk from host cell proteins in CHO-based protein production.Biotechnol Bioeng2014
24525618Cross-conservation of T-cell epitopes: now even more relevant to (H7N9) influenza vaccine design.Hum Vaccin Immunother2014
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Collaborators

University of Georgia
Co-authored papers 102
EpiVax Inc.
Co-authored papers 55
University of Colorado - Anschutz Medical Campus
Co-authored papers 11
Center for Vaccines and Immunology, University of Georgia
Co-authored papers 7
Center for Natural Products Research, University of Havana
Co-authored papers 7
University of Massachusetts Medical School
Co-authored papers 6
Rhode Island Hospital and the Warren Alpert Medical School of Brown University
Co-authored papers 6
Brown University, Kilguss Institut
Co-authored papers 5
Brock University
Co-authored papers 4
Brown University, Rhode Island Providence VA Medical Center
Co-authored papers 4
University of British Columbia
Co-authored papers 4
University of Copenhagen
Co-authored papers 4
Co-authored papers 3
Wistar Institute
Co-authored papers 3
University of Science
Co-authored papers 3
Drexel University College of Medicine
Co-authored papers 2
University of Massachusetts Chan Medical School
Co-authored papers 2
Saint Louis University School of Medicine
Co-authored papers 2
Faculty of Medicine and Odonto-Stomatology (FMOS)/University of Sciences
Co-authored papers 2
Warren Alpert School of Medicine at Brown University
Co-authored papers 2
EpiVax Inc.
Co-authored papers 2
Dana-Farber Cancer Institute, Harvard Medical School
Co-authored papers 2
Daejeon St. Mary's Hospital, College of Medicine, The Catholic University of Korea
Co-authored papers 2
Precision Immunology Institute, Icahn School of Medicine at Mount Sinai
Co-authored papers 1
Co-authored papers 1
McLean Hospital and Program in Neuroscience, Harvard Medical School
Co-authored papers 1
University of Sciences
Co-authored papers 1
Universite Libre de Bruxelles
Co-authored papers 1
France French Academy of Pharmacy
Co-authored papers 1
Massachusetts General Hospital
Co-authored papers 1