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Author Details

Sasan Zandi
University of Toronto
2006
31
21
PMIDPaper TitleJournal TitlePublished Year
36763002In Vivo Screening Unveils Pervasive RNA-Binding Protein Dependencies in Leukemic Stem Cells and Identifies ELAVL1 as a Therapeutic Target.Blood Cancer Discov2023
36201335Blastic plasmacytoid dendritic cell neoplasm in ocular adnexa.Blood2022
33242413The Transition from Quiescent to Activated States in Human Hematopoietic Stem Cells Is Governed by Dynamic 3D Genome Reorganization.Cell Stem Cell2021
33958784A latent subset of human hematopoietic stem cells resists regenerative stress to preserve stemness.Nat Immunol2021
31990679Cellular and molecular architecture of hematopoietic stem cells and progenitors in genetic models of bone marrow failure.JCI Insight2020
30655374Resolution of celiac disease, IgA deficiency and platelet refractoriness after allogeneic bone marrow transplantation for acute leukemia.Haematologica2019
30796022A stemness screen reveals <i>C3orf54/INKA1</i> as a promoter of human leukemia stem cell latency.Blood2019
29126030Evaluating the effect of adding Fish oil to Fingolimod on TNF-α, IL1β, IL6, and IFN-γ in patients with relapsing-remitting multiple sclerosis: A double-blind randomized placebo-controlled trial.Clin Neurol Neurosurg2017
26859458Truncating Erythropoietin Receptor Rearrangements in Acute Lymphoblastic Leukemia.Cancer Cell2016
26541609Distinct routes of lineage development reshape the human blood hierarchy across ontogeny.Science2016
25704240CDK6 levels regulate quiescence exit in human hematopoietic stem cells.Cell Stem Cell2015
26321221Efficacy of Retinoids in IKZF1-Mutated BCR-ABL1 Acute Lymphoblastic Leukemia.Cancer Cell2015
26440972Aging, clonal hematopoiesis and preleukemia: not just bad luck?Int J Hematol2015
24154973Identification of genes expressed by immune cells of the colon that are regulated by colorectal cancer-associated variants.Int J Cancer2014
24522528Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia.Nature2014
24345756The evolution of cellular deficiency in GATA2 mutation.Blood2014
23708252The transcriptional architecture of early human hematopoiesis identifies multilevel control of lymphoid commitment.Nat Immunol2013
22608498Gene deregulation and chronic activation in natural killer cells deficient in the transcription factor ETS1.Immunity2012
23019372Single-cell analysis of early B-lymphocyte development suggests independent regulation of lineage specification and commitment in vivo.Proc Natl Acad Sci U S A2012
22777388p38 Mitogen-activated protein kinase/signal transducer and activator of transcription-3 pathway signaling regulates expression of inhibitory molecules in T cells activated by HIV-1-exposed dendritic cells.Mol Med2012
21469119A dose-dependent role for EBF1 in repressing non-B-cell-specific genes.Eur J Immunol2011
21652681IL-7 mediates Ebf-1-dependent lineage restriction in early lymphoid progenitors.Blood2011
19996414Single-cell analysis of the common lymphoid progenitor compartment reveals functional and molecular heterogeneity.Blood2010
20829349Interleukin-7-induced Stat-5 acts in synergy with Flt-3 signaling to stimulate expansion of hematopoietic progenitor cells.J Biol Chem2010
20969584Load and lock: the molecular mechanisms of B-lymphocyte commitment.Immunol Rev2010
20152025Genomics based analysis of interactions between developing B-lymphocytes and stromal cells reveal complex interactions and two-way communication.BMC Genomics2010
20304793Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion.Proc Natl Acad Sci U S A2010
18714008EBF1 is essential for B-lineage priming and establishment of a transcription factor network in common lymphoid progenitors.J Immunol2008
18495958B-lineage commitment prior to surface expression of B220 and CD19 on hematopoietic progenitor cells.Blood2008
17218387Ectopic expression of PAX5 promotes maintenance of biphenotypic myeloid progenitors coexpressing myeloid and B-cell lineage-associated genes.Blood2007
16882979Cytokines regulate postnatal hematopoietic stem cell expansion: opposing roles of thrombopoietin and LNK.Genes Dev2006
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Collaborators

Lund University, Linkoping University. .
Co-authored papers 13
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 13
Karolinska Institutet
Co-authored papers 9
Ontario Institute for Cancer Research
Co-authored papers 4
Ontario Institute for Cancer Research, University Avenue
Co-authored papers 3
Princess Margaret Cancer Centre
Co-authored papers 3
Nanfang Hospital and Basic Medical College, Southern Medical University
Co-authored papers 2
Ontario Institute for Cancer Research
Co-authored papers 2
The Hospital for Sick Children
Co-authored papers 2
St Jude Children's Research Hospital
Co-authored papers 2
University of California San Diego
Co-authored papers 2
University of Washington
Co-authored papers 2
St Jude Children's Research Hospital
Co-authored papers 2
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 2
2Ontario Institute for Cancer Research
Co-authored papers 2
Ontario Institute for Cancer Research
Co-authored papers 2
St Jude Children's Research Hospital
Co-authored papers 2
University of Washington
Co-authored papers 1
Ohio State University
Co-authored papers 1
Princess Margaret Cancer Research Centre
Co-authored papers 1
Center for Genomics and Systems Biology, New York University
Co-authored papers 1
Co-authored papers 1
Sino-French Hoffmann Institute, Guangzhou Medical University
Co-authored papers 1
Ontario Institute for Cancer Research
Co-authored papers 1
MRC Weatherall Institute of Molecular Medicine, University of Oxford
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National Jewish Health
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Yale University School of Medicine
Co-authored papers 1
Baylor College of Medicine
Co-authored papers 1
McGill University
Co-authored papers 1
Mayo Clinic
Co-authored papers 1