Author details

Full Name

Michael S Seaman

Affiliation

ORCID

Career Start Year

1994

Papers

309

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37535402	Anamnestic humoral correlates of immunity across SARS-CoV-2 variants of concern.		2023
36348617	Safety and Immunogenicity of Ad26-Vectored HIV Vaccine With Mosaic Immunogens and a Novel Mosaic Envelope Protein in HIV-Uninfected Adults: A Phase 1/2a Study.	Journal of Infectious Diseases	2023
37940661	Inadequate structural constraint on Fab approach rather than paratope elicitation limits HIV-1 MPER vaccine utility.		2023
37734373	Mpox infection protects against re-challenge in rhesus macaques.		2023
37577493	SARS-CoV-2 Viral Clearance and Evolution Varies by Extent of Immunodeficiency.	medRxiv	2023
37577118	Delayed and Attenuated Antibody Responses to Coronavirus Disease 2019 Vaccination With Poor Cross-Variant Neutralization in Solid-Organ Transplant Recipients-A Prospective Longitudinal Study.		2023
37957379	Dynamics and durability of HIV-1 neutralization are determined by viral replication.	Nat Med	2023
36961924	Indoline CD4-mimetic compounds mediate potent and broad HIV-1 inhibition and sensitization to antibody-dependent cellular cytotoxicity.	Proc Natl Acad Sci U S A	2023
36763635	CD4 binding site immunogens elicit heterologous anti-HIV-1 neutralizing antibodies in transgenic and wild-type animals.	Sci Immunol	2023
37384759	Neutralization profiles of HIV-1 viruses from the VRC01 Antibody Mediated Prevention (AMP) trials.		2023
37249911	Divide and conquer: broadly neutralizing antibody combinations for improved HIV-1 viral coverage.		2023
36625252	Broadly neutralizing antibody-mediated protection against simian-HIV infection among macaques with vaginal sexually transmitted infections.		2023
37433296	Anti-V1/V3-glycan broadly HIV-1 neutralizing antibodies in a post-treatment controller.		2023
37430064	Structural and functional characteristics of the SARS-CoV-2 Omicron subvariant BA.2 spike protein.		2023
36729903	Bispecific antibody CAP256.J3LS targets V2-apex and CD4-binding sites with high breadth and potency.	MAbs	2023
37425731	Inadequate structural constraint on Fab approach rather than paratope elicitation limits HIV-1 MPER vaccine utility.		2023
35262094	Vaccine Breakthrough Infection with the SARS-CoV-2 Delta or Omicron (BA.1) Variant Leads to Distinct Profiles of Neutralizing Antibody Responses.		2022
35452593	Structural and functional impact by SARS-CoV-2 Omicron spike mutations.	Cell Rep	2022
35960796	A naturally arising broad and potent CD4-binding site antibody with low somatic mutation.	Sci Adv	2022
35650437	Combination anti-HIV antibodies provide sustained virological suppression.	Nature	2022
36284200	Engineering of HIV-1 neutralizing antibody CAP256V2LS for manufacturability and improved half life.	Scientific Reports	2022
36214224	Vaccine breakthrough infection leads to distinct profiles of neutralizing antibody responses by SARS-CoV-2 variant.	JCI insight	2022
35551291	Safety and antiviral activity of triple combination broadly neutralizing monoclonal antibody therapy against HIV-1: a phase 1 clinical trial.	Nature Medicine	2022
35418681	Prolonged viral suppression with anti-HIV-1 antibody therapy.	Nature	2022
35547850	Structural and functional characteristics of SARS-CoV-2 Omicron subvariant BA.2 spike.		2022
35922441	Identification of IOMA-class neutralizing antibodies targeting the CD4-binding site on the HIV-1 envelope glycoprotein.	Nat Commun	2022
36412833	Rational Design and In Vivo Characterization of mRNA-Encoded Broadly Neutralizing Antibody Combinations against HIV-1.	Antibodies	2022
36395347	Complementary antibody lineages achieve neutralization breadth in an HIV-1 infected elite neutralizer.	PLoS Pathog	2022
36453881	Subtle Longitudinal Alterations in Env Sequence Potentiate Differences in Sensitivity to Broadly Neutralizing Antibodies following Acute HIV-1 Subtype C Infection.	J Virol	2022
35064083	Engineering pan-HIV-1 neutralization potency through multispecific antibody avidity.	Proceedings of the National Academy of Sciences of the United States of America	2022
35313592	Functional analyses and single cell immunoprofiling uncover sex-specific differences in SARS-CoV2 immune memory development.	Res Sq	2022
35230385	Epitope convergence of broadly HIV-1 neutralizing IgA and IgG antibody lineages in a viremic controller.	J Exp Med	2022
35013325	Passive transfer of Ad26.COV2.S-elicited IgG from humans attenuates SARS-CoV-2 disease in hamsters.	npj Vaccines	2022
34697307	Antibody elicited by HIV-1 immunogen vaccination in macaques displaces Env fusion peptide and destroys a neutralizing epitope.	npj Vaccines	2021
34019795	Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies.	Cell	2021
33966028	Broadly neutralizing antibody-mediated protection of macaques against repeated intravenous exposures to simian-human immunodeficiency virus.	AIDS	2021
33704352	Immunogenicity of the Ad26.COV2.S Vaccine for COVID-19.	JAMA	2021
34015271	B cell genomics behind cross-neutralization of SARS-CoV-2 variants and SARS-CoV.	Cell	2021
34168070	Structural basis for enhanced infectivity and immune evasion of SARS-CoV-2 variants.	Science	2021
33893169	Correlates of Neutralization against SARS-CoV-2 Variants of Concern by Early Pandemic Sera.	Journal of Virology	2021
33843586	Distinct clonal evolution of B-cells in HIV controllers with neutralizing antibody breadth.	eLife	2021
33880477	Structural basis for enhanced infectivity and immune evasion of SARS-CoV-2 variants.		2021
33511233	Poststudy Point-of-Care Oral Fluid Testing in Human Immunodeficiency Virus-1 Vaccinees.	Open Forum Infectious Diseases	2021
34038720	Mining HIV controllers for broad and functional antibodies to recognize and eliminate HIV-infected cells.	Cell Reports	2021
33827946	Rational Engraftment of Quaternary-Interactive Acidic Loops for Anti-HIV-1 Antibody Improvement.	Journal of Virology	2021
34086838	Structural and genetic convergence of HIV-1 neutralizing antibodies in vaccinated non-human primates.	PLoS Pathogens	2021
33758863	Memory B cell repertoire for recognition of evolving SARS-CoV-2 spike.	bioRxiv	2021
34332650	Memory B cell repertoire for recognition of evolving SARS-CoV-2 spike.	Cell	2021
34354713	Broadly Neutralizing Antibodies for HIV-1 Prevention.	Frontiers in Immunology	2021
33298542	Neutralizing Activity of Broadly Neutralizing anti-HIV-1 Antibodies against Primary African Isolates.	Journal of Virology	2021