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Author Details

Susanne Heynen-Genel
Cancer Center, Sanford Burnham Prebys Medical Discovery Institute
2002
23
16
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
33632871Identification and Characterization of IMD-0354 as a Glutamine Carrier Protein Inhibitor in Melanoma.Mol Cancer Ther2021
27031987Cardiac Glycosides Activate the Tumor Suppressor and Viral Restriction Factor Promyelocytic Leukemia Protein (PML).PLoS One2016
27829216ERN1 and ALPK1 inhibit differentiation of bi-potential tumor-initiating cells in human breast cancer.Oncotarget2016
27385333Protein kinase A can block EphA2 receptor-mediated cell repulsion by increasing EphA2 S897 phosphorylation.Mol Biol Cell2016
27033521Genome-wide screen identifies novel machineries required for both ciliogenesis and cell cycle arrest upon serum starvation.Biochim Biophys Acta2016
26026149Functional genome-wide siRNA screen identifies KIAA0586 as mutated in Joubert syndrome.Elife2015
23989452Identification of Inhibitors of triacylglyceride accumulation in muscle cells: comparing HTS results from 1536-well plate-based and high-content platforms.J Biomol Screen2014
24448648Roquin-2 promotes ubiquitin-mediated degradation of ASK1 to regulate stress responses.Sci Signal2014
23589174Inhibition of melanoma growth by small molecules that promote the mitochondrial localization of ATF2.Clin Cancer Res2013
24611085Discovery of ML314, a Brain Penetrant Non-Peptidic β-Arrestin Biased Agonist of the Neurotensin NTR1 Receptor.ACS Med Chem Lett2013
24274581Identification of the GPR55 antagonist binding site using a novel set of high-potency GPR55 selective ligands.Biochemistry2013
22860749Functional genomic and high-content screening for target discovery and deconvolution.Expert Opin Drug Discov2012
22737280Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist Chemotypes through a HTS and Hit Refinement Strategy.ACS Chem Neurosci2012
21233309A high-content screening (HCS) assay for the identification of chemical inducers of PML oncogenic domains (PODs).J Biomol Screen2011
21791703A cell-based high-content screening assay reveals activators and inhibitors of cancer cell invasion.Sci Signal2011
21900202Optimization and application of median filter corrections to relieve diverse spatial patterns in microtiter plate data.J Biomol Screen2011
21534610Identification of the GPR55 agonist binding site using a novel set of high-potency GPR55 selective ligands.Biochemistry2011
20393563Functional genomic screen for modulators of ciliogenesis and cilium length.Nature2010
20826425Targeting of the orphan receptor GPR35 by pamoic acid: a potent activator of extracellular signal-regulated kinase and β-arrestin2 with antinociceptive activity.Mol Pharmacol2010
20547533Phenothiazine neuroleptics signal to the human insulin promoter as revealed by a novel high-throughput screen.J Biomol Screen2010
20230301Hybrid median filter background estimator for correcting distortions in microtiter plate data.Assay Drug Dev Technol2010
16305306Statistics of assay validation in high throughput cell imaging of nuclear factor kappaB nuclear translocation.Assay Drug Dev Technol2005
12552619Advances in molecular labeling, high throughput imaging and machine intelligence portend powerful functional cellular biochemistry tools.J Cell Biochem Suppl2002
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Collaborators

Sanford-Burnham-Prebys Medical Discovery Institute
Co-authored papers 5
University of California
Co-authored papers 3
Chugai Pharmaceutical Co.
Co-authored papers 3
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Co-authored papers 3
Korea Advanced Institute of Science and Technology (KAIST)
Co-authored papers 3
Soonchunhyang University College of Medicine, Bucheon Hospital
Co-authored papers 3
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Co-authored papers 2
University of California San Diego
Co-authored papers 2
Rady Children's Institute for Genomic Medicine, University of California
Co-authored papers 2
Co-authored papers 2
Co-authored papers 2
Co-authored papers 2
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 2
Radboud University Medical Center
Co-authored papers 1
Fondazione IRCCS Casa Sollievo della Sofferenza
Co-authored papers 1
Oregon Health & Science University
Co-authored papers 1
Sanford-Burnham Medical Research Institute
Co-authored papers 1
Fondazione IRCCS Istituto Neurologico Carlo Besta
Co-authored papers 1
Children's University Hospital
Co-authored papers 1
New York University Cancer Institute, New York University School of Medicine
Co-authored papers 1
Sanford Burnham Prebys Medical Discovery Institute
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Cancer Center, Sanford Burnham Prebys Medical Discovery Institute
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American University of Beirut Medical Center
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University of Oslo
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University of Leeds Leeds Institute of Medical Research at St James's
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Broad Institute of MIT and Harvard
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University of Minnesota
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Children's University Hospital, Bern University Hospital, University of Bern
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Cancer Center, Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 1