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Author Details

Michael C Wiener
University of Virginia
1986
55
33
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
32199981Ste24: An Integral Membrane Protein Zinc Metalloprotease with Provocative Structure and Emergent Biology.J Mol Biol2020
31644822The tripartite architecture of the eukaryotic integral membrane protein zinc metalloprotease Ste24.Proteins2020
30082509Phosphoramidon inhibits the integral membrane protein zinc metalloprotease ZMPSTE24.Acta Crystallogr D Struct Biol2018
28119065Acquisition of accurate data from intramolecular quenched fluorescence protease assays.Anal Biochem2017
27129777Ste24p Mediates Proteolysis of Both Isoprenylated and Non-prenylated Oligopeptides.J Biol Chem2016
26175898Integral membrane proteins and free electron lasers - a compatible couple indeed!IUCrJ2015
24739163A critical evaluation of in silico methods for detection of membrane protein intrinsic disorder.Biophys J2014
23539602Structure of the integral membrane protein CAAX protease Ste24p.Science2013
23381628Coordinating the impact of structural genomics on the human α-helical transmembrane proteome.Nat Struct Mol Biol2013
21693645How hydrophobic molecules traverse the outer membranes of gram-negative bacteria.Proc Natl Acad Sci U S A2011
21539919The variable detergent sensitivity of proteases that are utilized for recombinant protein affinity tag removal.Protein Expr Purif2011
20153331Design and characterization of a constitutively open KcsA.FEBS Lett2010
20816073Conformational exchange in a membrane transport protein is altered in protein crystals.Biophys J2010
20667442A high-throughput differential filtration assay to screen and select detergents for membrane proteins.Anal Biochem2010
19747487Coupling of calcium and substrate binding through loop alignment in the outer-membrane transporter BtuB.J Mol Biol2009
17449669Mechanics of force propagation in TonB-dependent outer membrane transport.Biophys J2007
16741124Outer membrane active transport: structure of the BtuB:TonB complex.Science2006
17132858When worlds colloid.Protein Sci2006
16820681Crystallization and preliminary X-ray crystallographic analysis of the Escherichia coli outer membrane cobalamin transporter BtuB in complex with the carboxy-terminal domain of TonB.Acta Crystallogr Sect F Struct Biol Cryst Commun2006
15739205Comparative structural analysis of TonB-dependent outer membrane transporters: implications for the transport cycle.Proteins2005
16039843TonB-dependent outer membrane transport: going for Baroque?Curr Opin Struct Biol2005
14711520Membrane protein expression and production: effects of polyhistidine tag length and position.Protein Expr Purif2004
15325654A pedestrian guide to membrane protein crystallization.Methods2004
12509992Inhibition of tobacco etch virus protease activity by detergents.Protein Expr Purif2003
14499604The Escherichia coli outer membrane cobalamin transporter BtuB: structural analysis of calcium and substrate binding, and identification of orthologous transporters by sequence/structure conservation.J Mol Biol2003
12902336Enzymatic E-colicins bind to their target receptor BtuB by presentation of a small binding epitope on a coiled-coil scaffold.J Biol Chem2003
14528295The structure of BtuB with bound colicin E3 R-domain implies a translocon.Nat Struct Biol2003
12652322Substrate-induced transmembrane signaling in the cobalamin transporter BtuB.Nat Struct Biol2003
12595710Crystallization and initial X-ray diffraction of BtuB, the integral membrane cobalamin transporter of Escherichia coli.Acta Crystallogr D Biol Crystallogr2003
11790740Identification of the periplasmic cobalamin-binding protein BtuF of Escherichia coli.J Bacteriol2002
12077430Thiol-reactive lanthanide chelates for phasing protein X-ray diffraction data.Acta Crystallogr D Biol Crystallogr2002
10648805Expression, purification, and initial structural characterization of YadQ, a bacterial homolog of mammalian ClC chloride channel proteins.FEBS Lett2000
10986468Bacterial export takes its Tol.Structure2000
10933509Mesoscopic surfactant organization and membrane protein crystallization.Protein Sci2000
10548052Outer membrane protein A of E. coli folds into detergent micelles, but not in the presence of monomeric detergent.Protein Sci1999
9729746Ion-channel-forming colicins.Curr Opin Struct Biol1998
9009197Crystal structure of colicin Ia.Nature1997
8921199A lectin screening method for membrane glycoproteins: application to the human CHIP28 water channel (AQP-1).Anal Biochem1996
7532004Purification and structure-function analysis of native, PNGase F-treated, and endo-beta-galactosidase-treated CHIP28 water channels.Biochemistry1995
7552739The CHIP28 water channel visualized in ice by electron crystallography.Nat Struct Biol1995
7524655Projection structure of the CHIP28 water channel in lipid bilayer membranes at 12-A resolution.Biochemistry1994
8218256Secondary structure analysis of purified functional CHIP28 water channels by CD and FTIR spectroscopy.Biochemistry1993
1547330Structure of a fluid dioleoylphosphatidylcholine bilayer determined by joint refinement of x-ray and neutron diffraction data. II. Distribution and packing of terminal methyl groups.Biophys J1992
1547331Structure of a fluid dioleoylphosphatidylcholine bilayer determined by joint refinement of x-ray and neutron diffraction data. III. Complete structure.Biophys J1992
2069956Transbilayer distribution of bromine in fluid bilayers containing a specifically brominated analogue of dioleoylphosphatidylcholine.Biochemistry1991
1932548Structure of a fluid dioleoylphosphatidylcholine bilayer determined by joint refinement of x-ray and neutron diffraction data. I. Scaling of neutron data and the distributions of double bonds and water.Biophys J1991
2015381Fluid bilayer structure determination by the combined use of x-ray and neutron diffraction. I. Fluid bilayer models and the limits of resolution.Biophys J1991
2015382Fluid bilayer structure determination by the combined use of x-ray and neutron diffraction. II. "Composition-space" refinement method.Biophys J1991
2713444Relations for lipid bilayers. Connection of electron density profiles to other structural quantities.Biophys J1989
2713445Structure of the fully hydrated gel phase of dipalmitoylphosphatidylcholine.Biophys J1989
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Collaborators

Co-authored papers 6
University of California San Francisco
Co-authored papers 4
Jacobs School of Medicine and Biomedical Sciences, University of Buffalo
Co-authored papers 2
University of Illinois at Urbana-Champaign
Co-authored papers 2
University of Rochester Medical Center
Co-authored papers 2
Georgia Institute of Technology
Co-authored papers 2
University of California San Francisco
Co-authored papers 1
University of California
Co-authored papers 1
Technical University of Munich (TUM)
Co-authored papers 1
iHuman Institute, ShanghaiTech University
Co-authored papers 1
Columbia University
Co-authored papers 1
Harvard Medical School
Co-authored papers 1
University of California San Francisco
Co-authored papers 1
University of Colorado Boulder
Co-authored papers 1
Howard Hughes Medical Institute, California Institute of Technology
Co-authored papers 1
Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai
Co-authored papers 1
Skaggs School of Pharmacy and Pharmaceutical Sciences.
Co-authored papers 1
NYU School of Medicine
Co-authored papers 1
Institute for Advanced Study (TUM-IAS), TUM (Technische Universitat Munchen)
Co-authored papers 1
Institute for Protein Research, Osaka University
Co-authored papers 1
Biodesign Center for Applied Structural Discovery, Arizona State University
Co-authored papers 1
Co-authored papers 1
Co-authored papers 1
University of California san francisco
Co-authored papers 1
University of Wisconsin-Madison
Co-authored papers 1