Author details

Full Name

Hanna E Abboud

Affiliation

ORCID

Career Start Year

1979

Papers

240

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36321974	Sustained Upregulation of Endothelial Nox4 Mediates Retinal Vascular Pathology in Type 1 Diabetes.		2023
33201372	Endothelium-specific deletion of Nox4 delays retinal vascular development and mitigates pathological angiogenesis.	Angiogenesis	2021
32240965	Interplay between RNA-binding protein HuR and Nox4 as a novel therapeutic target in diabetic kidney disease.	Molecular Metabolism	2020
29360107	Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.	Sci Data	2018
29491408	Nox4 is a Target for Tuberin Deficiency Syndrome.	Scientific Reports	2018
29269120	Mouse Metanephric Mesenchymal Cell-Derived Angioblasts Undergo Vasculogenesis in Three-Dimensional Culture.	American Journal of Pathology	2018
28188286	Hydrogen sulfide inhibits high glucose-induced NADPH oxidase 4 expression and matrix increase by recruiting inducible nitric oxide synthase in kidney proximal tubular epithelial cells.	Journal of Biological Chemistry	2017
28469469	Tryptophan Metabolism in Patients With Chronic Kidney Disease Secondary to Type 2 Diabetes: Relationship to Inflammatory Markers.	International Journal of Tryptophan Research	2017
28341696	A Low-Frequency Inactivating <i>AKT2</i> Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk.	Diabetes	2017
28838971	A Loss-of-Function Splice Acceptor Variant in <i>IGF2</i> Is Protective for Type 2 Diabetes.	Diabetes	2017
29257133	Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.	Sci Data	2017
27648011	Genetic Variants in Toll-Like Receptor 4 Gene and Their Association Analysis with Estimated Glomerular Filtration Rate in Mexican American Families.	CardioRenal Medicine	2016
27393154	mTORC2 Signaling Regulates Nox4-Induced Podocyte Depletion in Diabetes.	Antioxidants and Redox Signaling	2016
27142425	Selecting SNPs informative for African, American Indian and European Ancestry: application to the Family Investigation of Nephropathy and Diabetes (FIND).	BMC Genomics	2016
27278252	Tuberin regulates reactive oxygen species in renal proximal cells, kidney from rodents, and kidney from patients with tuberous sclerosis complex.	Cancer Science	2016
27398621	The genetic architecture of type 2 diabetes.	Nature	2016
26067231	Metformin prevents renal interstitial fibrosis in mice with unilateral ureteral obstruction.	Molecular and Cellular Endocrinology	2015
25885044	Evaluation of neurotrophic tyrosine receptor kinase 2 (NTRK2) as a positional candidate gene for variation in estimated glomerular filtration rate (eGFR) in Mexican American participants of San Antonio Family Heart study.	J Biomed Sci	2015
25753172	Membranous nephropathy and cerebellar degeneration with anti-GAD antibodies in type 2 diabetes mellitus.	Acta Diabetologica	2015
25589557	NADPH oxidase 4 induces cardiac fibrosis and hypertrophy through activating Akt/mTOR and NFÎºB signaling pathways.	Circulation	2015
25825489	Nox2 mediates skeletal muscle insulin resistance induced by a high fat diet.	Journal of Biological Chemistry	2015
25656366	Targeting NADPH oxidase with a novel dual Nox1/Nox4 inhibitor attenuates renal pathology in type 1 diabetes.		2015
26098468	Layer-Specific Manganese-Enhanced MRI of the Diabetic Rat Retina in Light and Dark Adaptation at 11.7 Tesla.	Investigative Ophthalmology and Visual Science	2015
26305897	Genome-Wide Association and Trans-ethnic Meta-Analysis for Advanced Diabetic Kidney Disease: Family Investigation of Nephropathy and Diabetes (FIND).	PLoS Genet	2015
26071397	Activation of AMP-activated protein kinase prevents TGF-Î²1-induced epithelial-mesenchymal transition and myofibroblast activation.	Am J Pathol	2015
26240579	Diabetic Cardiomyopathy; Summary of 41 Years.	Korean Circulation Journal	2015
24740537	A positive feedback loop involving Erk5 and Akt turns on mesangial cell proliferation in response to PDGF.	American Journal of Physiology - Cell Physiology	2014
25333702	TGFÎ²-induced deptor suppression recruits mTORC1 and not mTORC2 to enhance collagen I (Î±2) gene expression.	PLoS ONE	2014
24915262	Association of a low-frequency variant in HNF1A with type 2 diabetes in a Latino population.	JAMA	2014
24899059	ADAM17 promotes proliferation of collecting duct kidney epithelial cells through ERK activation and increased glycolysis in polycystic kidney disease.		2014
25016284	microRNA-21-induced dissociation of PDCD4 from rictor contributes to Akt-IKKÎ²-mTORC1 axis to regulate renal cancer cell invasion.	Experimental Cell Research	2014
23557706	Mammalian target of rapamycin regulates Nox4-mediated podocyte depletion in diabetic renal injury.		2013
24358131	A genome-wide search for linkage of estimated glomerular filtration rate (eGFR) in the Family Investigation of Nephropathy and Diabetes (FIND).	PLoS One	2013
23981302	NFÎºB-mediated cyclin D1 expression by microRNA-21 influences renal cancer cell proliferation.	Cellular Signalling	2013
23804455	The antioxidant silybin prevents high glucose-induced oxidative stress and podocyte injury in vitro and in vivo.		2013
24379826	Genome-wide association analysis confirms and extends the association of SLC2A9 with serum uric acid levels to Mexican Americans.	Front Genet	2013
24057238	Susceptibility gene search for nephropathy and related traits in Mexican-Americans.	Molecular Biology Reports	2013
23362262	Transforming growth factor Î² integrates Smad 3 to mechanistic target of rapamycin complexes to arrest deptor abundance for glomerular mesangial cell hypertrophy.	Journal of Biological Chemistry	2013
23682294	Improving learning about familial risks using a multicomponent approach: the GRACE program.	Personalized Medicine	2013
23678045	ADAM17 mediates Nox4 expression and NADPH oxidase activity in the kidney cortex of OVE26 mice.		2013
23633050	Synthetic oleanane triterpenoids: magic bullets or not?	Kidney International	2013
22138298	Reciprocal induction of simple organogenesis by mouse kidney progenitor cells in three-dimensional co-culture.	American Journal of Pathology	2012
22552392	Renal histopathology of a baboon model with type 2 diabetes.	Toxicol Pathol	2012
22685542	microRNA-21 governs TORC1 activation in renal cancer cell proliferation and invasion.	PLoS ONE	2012
22617042	The Gly(972)Arg variant of human IRS1 gene is associated with variation in glomerular filtration rate likely through impaired insulin receptor signaling.		2012
22414873	Mesangial cell biology.	Experimental Cell Research	2012
22445478	Diabetic nephropathy among Mexican Americans.	Clinical Nephrology	2012
22234462	Prediabetic nephropathy as an early consequence of the high-calorie/high-fat diet: relation to oxidative stress.	Endocrinology	2012
22184110	Unrestrained mammalian target of rapamycin complexes 1 and 2 increase expression of phosphatase and tensin homolog deleted on chromosome 10 to regulate phosphorylation of Akt kinase.	Journal of Biological Chemistry	2012
22158625	Hydrogen sulfide inhibits high glucose-induced matrix protein synthesis by activating AMP-activated protein kinase in renal epithelial cells.	Journal of Biological Chemistry	2012