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Author Details
Full Name
Ronald T Raines
Affiliation
Massachusetts Institute of Technology
ORCID
Career Start Year
1981
Papers
424
H Index
81
Expertise
CM4AI Collaborator
PMID
Paper Title
Journal Title
Published Year
36374612
Emergent Organoboron Acid Catalysts.
J Org Chem
2024
37997193
Synthetic Collagen Hydrogels through Symmetric Self-Assembly of Small Peptides.
Adv Sci (Weinh)
2024
36793428
Inhibition of HIV-1 Protease by a Boronic Acid with High Oxidative Stability.
ACS Med Chem Lett
2023
37530571
Fluorescent Guanidinium-Azacarbazole for Oxoanion Binding in Water.
J Org Chem
2023
37860707
Computational study of an oxetane 4<i>H</i>-pyrazole as a Diels-Alder diene.
Tetrahedron Lett
2023
37750823
Bayesian Inference Elucidates the Catalytic Competency of the SARS-CoV-2 Main Protease 3CL<sup>pro</sup>.
Anal Chem
2023
37780415
Differential membrane binding of α/β-peptide foldamers: implications for cellular delivery and mitochondrial targeting.
Aust J Chem
2023
37930825
Detection of Pulmonary Fibrosis with a Collagen-Mimetic Peptide.
ACS Sens
2023
36987784
Bioorthogonal 4<i>H</i>-pyrazole "click" reagents.
Chem Commun (Camb)
2023
36968255
Spirocyclization enhances the Diels-Alder reactivities of geminally substituted cyclopentadienes and 4<i>H</i>-pyrazoles.
J Phys Org Chem
2023
36964973
Chemoselective Caging of Carboxyl Groups for On-Demand Protein Activation with Small Molecules.
Angew Chem Int Ed Engl
2023
36920197
Modular Diazo Compound for the Bioreversible Late-Stage Modification of Proteins.
J Am Chem Soc
2023
35084170
Bifunctional Peptide that Anneals to Damaged Collagen and Clusters TGF-β Receptors Enhances Wound Healing.
ACS Chem Biol
2022
35527228
Context-Dependence of the Reactivity of Cysteine and Lysine Residues.
Chembiochem
2022
36036888
Host-Guest Complexation by β-Cyclodextrin Enhances the Solubility of an Esterified Protein.
Mol Pharm
2022
34886717
Emerging biological functions of ribonuclease 1 and angiogenin.
Crit Rev Biochem Mol Biol
2022
35331374
Assessing and utilizing esterase specificity in antimicrobial prodrug development.
Methods Enzymol
2022
33296182
Semisynthesis of Human Ribonuclease-S.
Bioconjug Chem
2021
33653951
Boronic acid with high oxidative stability and utility in biological contexts.
Proc Natl Acad Sci U S A
2021
33877811
Endogenous Enzymes Enable Antimicrobial Activity.
ACS Chem Biol
2021
33651602
Click Chemistry with Cyclopentadiene.
Chem Rev
2021
33818092
Two-Step Synthesis of α-Aryl-α-diazoamides as Modular Bioreversible Labels.
Org Lett
2021
34702287
Ribonuclease zymogen induces cytotoxicity upon HIV-1 infection.
AIDS Res Ther
2021
34151576
Acceleration of 1,3-Dipolar Cycloadditions by Integration of Strain and Electronic Tuning.
J Am Chem Soc
2021
34290459
Geminal Repulsion Disrupts Diels-Alder Reactions of Geminally Substituted Cyclopentadienes and 4<i>H</i>-Pyrazoles.
Tetrahedron
2021
32159956
Cyclic Peptide Mimetic of Damaged Collagen.
Biomacromolecules
2020
31930911
Stereoelectronic Effects Impact Glycan Recognition.
J Am Chem Soc
2020
31895554
Templated Collagen "Double Helices" Maintain Their Structure.
J Am Chem Soc
2020
33085477
Triple, Mutually Orthogonal Bioorthogonal Pairs through the Design of Electronically Activated Sulfamate-Containing Cycloalkynes.
J Am Chem Soc
2020
33059455
Daniel S. Kemp (1936-2020): A Pioneer of Bioorganic Chemistry.
ACS Chem Biol
2020
33054163
Antimicrobial Synergy of a Ribonuclease and a Peptide Secreted by Human Cells.
ACS Infect Dis
2020
33319995
Palladium-Protein Oxidative Addition Complexes by Amine-Selective Acylation.
J Am Chem Soc
2020
32715561
Optical imaging of collagen fiber damage to assess thermally injured human skin.
Wound Repair Regen
2020
32701272
<i>n</i>â¿¿Ï¿* Interactions Modulate the Disulfide Reduction Potential of Epidithiodiketopiperazines.
J Am Chem Soc
2020
32530082
Differential Effects of Nitrogen Substitution in 5- and 6-Membered Aromatic Motifs.
Chemistry
2020
32180548
Molecular basis for catabolism of the abundant metabolite <i>trans</i>-4-hydroxy-L-proline by a microbial glycyl radical enzyme.
Elife
2020
32413256
Role for Cell-Surface Collagen of <i>Streptococcus pyogenes</i> in Infections.
ACS Infect Dis
2020
32544330
Structure and Dynamics of N-Glycosylated Human Ribonuclease 1.
Biochemistry
2020
32170021
<i>Hox</i> genes maintain critical roles in the adult skeleton.
Proc Natl Acad Sci U S A
2020
32166866
Differential Effects of Nitrogen Substitution in 5- and 6-Membered Aromatic Motifs.
Chemistry
2020
32486503
Synthesis and Diels-Alder Reactivity of 4-Fluoro-4-Methyl-4<i>H</i>-Pyrazoles.
Int J Mol Sci
2020
32293886
Disulfide Chromophores Arise from Stereoelectronic Effects.
J Phys Chem B
2020
30452903
Collagen Prolyl Hydroxylases Are Bifunctional Growth Regulators in Melanoma.
J Invest Dermatol
2019
31720665
Optimization of interstrand interactions enables burn detection with a collagen-mimetic peptide.
Org Biomol Chem
2019
31651164
Nucleoside Tetra- and Pentaphosphates Prepared Using a Tetraphosphorylation Reagent Are Potent Inhibitors of Ribonuclease A.
J Am Chem Soc
2019
31589054
Hyperconjugative Antiaromaticity Activates 4<i>H</i>-Pyrazoles as Inverse-Electron-Demand Diels-Alder Dienes.
Org Lett
2019
31243961
Secondary Forces in Protein Folding.
ACS Chem Biol
2019
31431502
Angiogenin activates the astrocytic Nrf2/antioxidant-response element pathway and thereby protects murine neurons from oxidative stress.
J Biol Chem
2019
31306518
Circular zymogens of human ribonuclease 1.
Protein Sci
2019
31247727
Terbium(III) Luminescence-Based Assay for Esterase Activity.
Anal Chem
2019
1 - 50 of 424
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Collaborators
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Broad Institute of MIT and Harvard
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Exercise Medicine Research Institute, Edith Cowan University
Co-authored papers
9
Stephen M Fuchs
Tufts University
Co-authored papers
7
Marcia C Haigis
Co-authored papers
7
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Whitehead Institute for Biomedical Research
Co-authored papers
7
Laura L Kiessling
Massachusetts Institute of Technology
Co-authored papers
7
George N Phillips
Rice University
Co-authored papers
6
John L Markley
University of Wisconsin-Madison
Co-authored papers
5
Valerie T Ressler
Promega Corporation
Co-authored papers
4
Kevin W Eliceiri
University of Wisconsin-Madison
Co-authored papers
2
Christopher J Murphy
Co-authored papers
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Vadim N Gladyshev
Brigham and Women's Hospital
Co-authored papers
1
Rubeta N Matin
Oxford University Hospitals NHS Foundation Trust
Co-authored papers
1
Charles Steenbergen
Co-authored papers
1
Wendell A Lim
University of California san francisco
Co-authored papers
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Elizabeth Murphy
Co-authored papers
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Daniel B Kearns
Indiana University
Co-authored papers
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Julie C Mitchell
Co-authored papers
1
David H O'Connor
Co-authored papers
1
Andrzej Joachimiak
Center for Structural Biology of Infectious Diseases, University of Chicago
Co-authored papers
1
Phillip D Zamore
Co-authored papers
1
Bin Zhang
Massachusetts Institute of Technology
Co-authored papers
1
Andrew P Latham
Massachusetts Institute of Technology, University of California, San Francisco, University of Notre Dame
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1
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Foundation for Applied Molecular Evolution
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1
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