Author details

Full Name

Jeremy Luban

Affiliation

ORCID

Career Start Year

1983

Papers

157

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37246708	Reducing the inherent auto-inhibitory interaction within the pegRNA enhances prime editing efficiency.		2023
37843371	Emerging role of cyclophilin A in HIV-1 infection: from producer cell to the target cell nucleus.		2023
37034621	S:D614G and S:H655Y are gateway mutations that act epistatically to promote SARS-CoV-2 variant fitness.	bioRxiv	2023
36656774	The 2022 RSV surge was driven by multiple viral lineages.	medRxiv	2023
37137903	Detergent modulates the conformational equilibrium of SARS-CoV-2 Spike during cryo-EM structural determination.	Nat Commun	2023
36812457	Viral Lineages in the 2022 RSV Surge in the United States.	N Engl J Med	2023
36748341	Purification and structure of luminal domain C of human Niemann-Pick C1 protein.		2023
37382276	Transcriptional and chromatin profiling of human blood innate lymphoid cell subsets sheds light on HIV-1 pathogenesis.	EMBO J	2023
35323111	Conformational dynamics and allosteric modulation of the SARS-CoV-2 spike.	Elife	2022
36214224	Vaccine breakthrough infection leads to distinct profiles of neutralizing antibody responses by SARS-CoV-2 variant.	JCI insight	2022
36198312	Multimodal surveillance of SARS-CoV-2 at a university enables development of a robust outbreak response framework.	Med	2022
35608456	Analysis of 6.4 million SARS-CoV-2 genomes identifies mutations associated with fitness.	Science	2022
35275061	Innate lymphoid cells and COVID-19 severity in SARS-CoV-2 infection.	Elife	2022
34940876	Consulting the Oracle of SARS-CoV-2 Infection.	Journal of Infectious Diseases	2022
35262094	Vaccine Breakthrough Infection with the SARS-CoV-2 Delta or Omicron (BA.1) Variant Leads to Distinct Profiles of Neutralizing Antibody Responses.		2022
33303686	Phylogenetic analysis of SARS-CoV-2 in Boston highlights the impact of superspreading events.	Science	2021
34224738	Targeting of the Tec Kinase ITK Drives Resolution of T Cell-Mediated Colitis and Emerges as Potential Therapeutic Option in Ulcerative Colitis.	Gastroenterology	2021
34140338	Lessons from a local effort to screen for SARS-CoV-2.	Proceedings of the National Academy of Sciences of the United States of America	2021
34325468	AIM2 regulates anti-tumor immunity and is a viable therapeutic target for melanoma.	J Exp Med	2021
33249060	The DHODH inhibitor PTC299 arrests SARS-CoV-2 replication and suppresses induction of inflammatory cytokines.	Virus Research	2021
32793904	The DHODH Inhibitor PTC299 Arrests SARS-CoV-2 Replication and Suppresses Induction of Inflammatory Cytokines.		2020
32066947	HIV-1-induced cytokines deplete homeostatic innate lymphoid cells and expand TCF7-dependent memory NK cells.	Nat Immunol	2020
31952352	Reporter Assays for Ebola Virus Nucleoprotein Oligomerization, Virion-Like Particle Budding, and Minigenome Activity Reveal the Importance of Nucleoprotein Amino Acid Position 111.	Viruses	2020
31952255	Real-Time Analysis of Individual Ebola Virus Glycoproteins Reveals Pre-Fusion, Entry-Relevant Conformational Dynamics.	Viruses	2020
32282853	TRIM34 restricts HIV-1 and SIV capsids in a TRIM5Î±-dependent manner.	PLoS Pathog	2020
32040508	Conformational changes in the Ebola virus membrane fusion machine induced by pH, Ca2+, and receptor binding.	PLoS Biol	2020
32991842	Structural and Functional Analysis of the D614G SARS-CoV-2 Spike Protein Variant.	Cell	2020
32755590	Single-Cell RNA Profiling Reveals Adipocyte to Macrophage Signaling Sufficient to Enhance Thermogenesis.	Cell Reports	2020
32869040	Phylogenetic analysis of SARS-CoV-2 in the Boston area highlights the role of recurrent importation and superspreading events.	medRxiv	2020
30892626	Enhanced Cas12a editing in mammalian cells and zebrafish.	Nucleic Acids Research	2019
31595085	Retraction Note: The hidden cost of genetic resistance to HIV-1.	Nature Medicine	2019
31607510	The piRNA Response to Retroviral Invasion of the Koala Genome.	Cell	2019
30593536	Human Anti-HIV-1 gp120 Monoclonal Antibodies with Neutralizing Activity Cloned from Humanized Mice Infected with HIV-1.	J Immunol	2019
31189110	TRIM5Î± Restricts Flavivirus Replication by Targeting the Viral Protease for Proteasomal Degradation.	Cell Rep	2019
31160816	The hidden cost of genetic resistance to HIV-1.	Nature Medicine	2019
29454939	Comparative Analysis of Immune Cells Reveals a Conserved Regulatory Lexicon.	Cell Syst	2018
30546110	Intron-containing RNA from the HIV-1 provirus activates type I interferon and inflammatory cytokines.	Nature Communications	2018
30297740	Primate immunodeficiency virus proteins Vpx and Vpr counteract transcriptional repression of proviruses by the HUSH complex.	Nature Microbiology	2018
29118121	HIV-1 R5 Macrophage-Tropic Envelope Glycoprotein Trimers Bind CD4 with High Affinity, while the CD4 Binding Site on Non-macrophage-tropic, T-Tropic R5 Envelopes Is Occluded.	J Virol	2018
29237846	The Three-Fold Axis of the HIV-1 Capsid Lattice Is the Species-Specific Binding Interface for TRIM5Î±.	Journal of Virology	2018
28199054	Optimization by infusion of multiple reaction monitoring transitions for sensitive quantification of peptides by liquid chromatography/mass spectrometry.	Rapid Communications in Mass Spectrometry	2017
27814506	Ebola Virus Glycoprotein with Increased Infectivity Dominated the 2013-2016 Epidemic.	Cell	2016
27107820	HIV-1 capsid is involved in post-nuclear entry steps.	Retrovirology	2016
27387471	Closing the net on retroviruses.	eLife	2016
27470110	End Sequence Analysis Toolkit (ESAT) expands the extractable information from single-cell RNA-seq data.	Genome Research	2016
26468522	TRIM5 Retroviral Restriction Activity Correlates with the Ability To Induce Innate Immune Signaling.	Journal of Virology	2016
26412574	Ranking Fragment Ions Based on Outlier Detection for Improved Label-Free Quantification in Data-Independent Acquisition LC-MS/MS.	Journal of Proteome Research	2015
25430050	Processing strategies and software solutions for data-independent acquisition in mass spectrometry.	Proteomics	2015
26181333	Lv4 Is a Capsid-Specific Antiviral Activity in Human Blood Cells That Restricts Viruses of the SIVMAC/SIVSM/HIV-2 Lineage Prior to Integration.	PLoS Pathogens	2015
26302369	The Use of Variable Q1 Isolation Windows Improves Selectivity in LC-SWATH-MS Acquisition.	Journal of Proteome Research	2015