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Author Details

Jane H Buckner
Center for Translational Immunology, Benaroya Research Institute at Virginia Mason
1995
166
51
PMIDPaper TitleJournal TitlePublished Year
36259174Association of Antibodies to Prevotella copri in Anti-Cyclic Citrullinated Peptide-Positive Individuals At Risk of Developing Rheumatoid Arthritis and in Patients With Early or Established Rheumatoid Arthritis.Arthritis Rheumatol2023
37758901Shifts in isoform usage underlie transcriptional differences in regulatory T cells in type 1 diabetes.Commun Biol2023
37481700Dual-locus, dual-HDR editing permits efficient generation of antigen-specific regulatory T cells with robust suppressive activity.Mol Ther2023
37493210Immune-related adverse events after immune check point inhibitors: Understanding the intersection with autoimmunity.Immunol Rev2023
37147460Down syndrome: insights into autoimmune mechanisms.Nat Rev Rheumatol2023
37406138Dysregulated IFN-γ signals promote autoimmunity in STAT1 gain-of-function syndrome.Sci Transl Med2023
37338983Diminished responses to mRNA-based SARS-CoV-2 vaccines in individuals with rheumatoid arthritis on immune-modifying therapies.JCI Insight2023
37101346Translational immunology: Applying fundamental discoveries to human health and autoimmune diseases.Eur J Immunol2023
36961507<i>PTPN22</i> R620W gene editing in T cells enhances low-avidity TCR responses.Elife2023
36741943Barriers to Screening: An Analysis of Factors Impacting Screening for Type 1 Diabetes Prevention Trials.J Endocr Soc2023
36598533Regulatory T cells suppress CD4+ effector T cell activation by controlling protein synthesis.J Exp Med2023
36894554SARS-CoV-2 mRNA vaccines decouple anti-viral immunity from humoral autoimmunity.Nat Commun2023
36658110Cytotoxic CD8<sup>+</sup> T cells target citrullinated antigens in rheumatoid arthritis.Nat Commun2023
35020411Deep immune phenotyping reveals similarities between aging, Down syndrome, and autoimmunity.Sci Transl Med2022
35573706Crosstalk between CD4 T cells and synovial fibroblasts from human arthritic joints promotes hyaluronan-dependent leukocyte adhesion and inflammatory cytokine expression in vitro.Matrix Biol Plus2022
35720397Relationship Between a Vitamin D Genetic Risk Score and Autoantibodies Among First-Degree Relatives of Probands With Rheumatoid Arthritis and Systemic Lupus Erythematosus.Front Immunol2022
35911690IL-6-Driven pSTAT1 Response Is Linked to T Cell Features Implicated in Early Immune Dysregulation.Front Immunol2022
36312783Mechanism-driven strategies for prevention of rheumatoid arthritis.Rheumatol Autoimmun2022
36197963Pancreatic islet-specific engineered T<sub>regs</sub> exhibit robust antigen-specific and bystander immune suppression in type 1 diabetes models.Sci Transl Med2022
36165179<i>CBLB</i> Deficiency in Human CD4<sup>+</sup> T Cells Results in Resistance to T Regulatory Suppression through Multiple Mechanisms.J Immunol2022
36288282Clonal IgA and IgG autoantibodies from individuals at risk for rheumatoid arthritis identify an arthritogenic strain of <i>Subdoligranulum</i>.Sci Transl Med2022
35980300Clinical and experimental treatment of type 1 diabetes.Clin Exp Immunol2022
35979360Genetic basis of defects in immune tolerance underlying the development of autoimmunity.Front Immunol2022
35288472Cutting Edge: Effect of Disease-Modifying Therapies on SARS-CoV-2 Vaccine-Induced Immune Responses in Multiple Sclerosis Patients.J Immunol2022
35058150Th17 cells: from gut homeostasis to CNS pathogenesis.Trends Immunol2022
35022272Fewer LAG-3<sup>+</sup> T Cells in Relapsing-Remitting Multiple Sclerosis and Type 1 Diabetes.J Immunol2022
32928740Factors associated with progression to inflammatory arthritis in first-degree relatives of individuals with RA following autoantibody positive screening in a non-clinical setting.Ann Rheum Dis2021
33507879Shared recognition of citrullinated tenascin-C peptides by T and B cells in rheumatoid arthritis.JCI Insight2021
33917702Early Prognostic Indicators of Subsequent Hospitalization in Patients with Mild COVID-19.J Clin Med2021
34521672Evaluating associations of joint swelling, joint stiffness and joint pain with physical activity in first-degree relatives of patients with rheumatoid arthritis: Studies of the Aetiology of Rheumatoid Arthritis (SERA), a prospective cohort study.BMJ Open2021
34747368IL-6 receptor blockade does not slow β cell loss in new-onset type 1 diabetes.JCI Insight2021
34537057HLA-DRB1 risk alleles for RA are associated with differential clinical responsiveness to abatacept and adalimumab: data from a head-to-head, randomized, single-blind study in autoantibody-positive early RA.Arthritis Res Ther2021
34740959The Autoimmune Risk R262W Variant of the Adaptor SH2B3 Improves Survival in Sepsis.J Immunol2021
34103397The dynamic epigenetic regulation of the inactive X chromosome in healthy human B cells is dysregulated in lupus patients.Proc Natl Acad Sci U S A2021
34326232Immunotherapy: Building a bridge to a cure for type 1 diabetes.Science2021
34342578Endomembrane targeting of human OAS1 p46 augments antiviral activity.Elife2021
34113805Multimodal analysis for human <i>ex vivo</i> studies shows extensive molecular changes from delays in blood processing.iScience2021
33368173Identifying the 'Achilles heel' of type 1 diabetes.Clin Exp Immunol2021
33381911Association of Lipid Mediators With Development of Future Incident Inflammatory Arthritis in an Anti-Citrullinated Protein Antibody-Positive Population.Arthritis Rheumatol2021
31600025Perceived Stress and Inflammatory Arthritis: A Prospective Investigation in the Studies of the Etiologies of Rheumatoid Arthritis Cohort.Arthritis Care Res (Hoboken)2020
31702112Multiparameter Analysis Identifies Heterogeneity in Knee Osteoarthritis Synovial Responses.Arthritis Rheumatol2020
33282427Sudden Cardiac Death due to Coronary Artery Vasculitis in a Patient with Relapsing Polychondritis.Case Rep Rheumatol2020
32493794Gene editing to induce FOXP3 expression in human CD4<sup>+</sup> T cells leads to a stable regulatory phenotype and function.Sci Transl Med2020
32484790Neutrophil extracellular traps mediate articular cartilage damage and enhance cartilage component immunogenicity in rheumatoid arthritis.JCI Insight2020
30390384Citrullinated Aggrecan Epitopes as Targets of Autoreactive CD4+ T Cells in Patients With Rheumatoid Arthritis.Arthritis Rheumatol2019
30988128Anticyclic Citrullinated Peptide Antibodies 3.1 and Anti-CCP-IgA Are Associated with Increasing Age in Individuals Without Rheumatoid Arthritis.J Rheumatol2019
31156654Corrigendum: Increased Binding of Specificity Protein 1 to the <i>IL21R</i> Promoter in B Cells Results in Enhanced B Cell Responses in Rheumatoid Arthritis.Front Immunol2019
30894366Dynamic Immune Phenotypes of B and T Helper Cells Mark Distinct Stages of T1D Progression.Diabetes2019
30740104The <i>TYK2</i>-P1104A Autoimmune Protective Variant Limits Coordinate Signals Required to Generate Specialized T Cell Subsets.Front Immunol2019
30888520Genetic Mechanisms Highlight Shared Pathways for the Pathogenesis of Polygenic Type 1 Diabetes and Monogenic Autoimmune Diabetes.Curr Diab Rep2019
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Collaborators

Sarah Alice Long
Center for Translational Immunology, Benaroya Research Institute at Virginia Mason
Co-authored papers 24
Carla J Greenbaum
Center for Interventional Immunology, Benaroya Research Institute at Virginia Mason
Co-authored papers 21
Gerald T Nepom
Wash Benaroya Research Institute at Virginia Mason
Co-authored papers 21
Jill M Norris
Co-authored papers 19
Karen Cerosaletti
Center for Translational Immunology
Co-authored papers 19
Peter K Gregersen
Co-authored papers 17
William W Kwok
Center for Translational Immunology, Benaroya Research Institute at Virginia Mason
Co-authored papers 12
Cate Speake
Center for Interventional Immunology, Benaroya Research Institute at Virginia Mason
Co-authored papers 11
William H Robinson
Co-authored papers 9
Kevan C Herold
Yale University
Co-authored papers 5
Patrick Concannon
Co-authored papers 5
Vivian H Gersuk
Center for Systems Immunology, Benaroya Research Institute
Co-authored papers 4
Peter S Linsley
8Benaroya Research Institute
Co-authored papers 4
Suna Onengut-Gumuscu
Co-authored papers 4
Zhong-Yin Zhang
Center for Cancer Research, and Institute for Drug Discovery, Purdue University
Co-authored papers 3
Catherine Pihoker
Co-authored papers 3
Lars Klareskog
Co-authored papers 3
Lars Rönnblom
Co-authored papers 3
Kendra A Young
Co-authored papers 3
Michael J Clare-Salzler
University of Florida College of Medicine
Co-authored papers 3
Janice Chen
Center for Translational Research
Co-authored papers 3
Carmen Mikacenic
Benaroya Research Institute at Virginia Mason
Co-authored papers 3
Bernard Khor
Center for Translational Immunology, Benaroya Research Institute at Virginia Mason
Co-authored papers 2
Jeffrey P Krischer
Health Informatics Institute, University of South Florida
Co-authored papers 2
Gary S Firestein
Co-authored papers 2
Joel M Guthridge
Arthritis and Clinical Immunology, Oklahoma Medical Research Foundation
Co-authored papers 2
Marc K Hellerstein
University of California berkeley
Co-authored papers 2
Stephen S Rich
Co-authored papers 2
Michael Gale
Center for Innate Immunity and Immune Disease, University of Washington
Co-authored papers 2
Fariba Barahmand-Pour
Benaroya Research Institute at Virginia Mason
Co-authored papers 2
Release 1.2