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Author Details

Spiros Denaxas
Institute of Health Informatics, University College London
2008
167
38
PMIDPaper TitleJournal TitlePublished Year
35290719Incidence, morbidity, mortality and disparities in dementia: A population linked electronic health records study of 4.3 million individuals.Alzheimers Dement2023
37919679Management and outcomes of myocardial infarction in people with impaired kidney function in England.BMC Nephrol2023
38019832Clustering long-term health conditions among 67728 people with multimorbidity using electronic health records in Scotland.PLoS One2023
37520147Trajectories in chronic disease accrual and mortality across the lifespan in Wales, UK (2005-2019), by area deprivation profile: linked electronic health records cohort study on 965,905 individuals.Lancet Reg Health Eur2023
37794179A taxonomy of early diagnosis research to guide study design and funding prioritisation.Br J Cancer2023
37649988Determining prescriptions in electronic healthcare record data: methods for development of standardized, reproducible drug codelists.JAMIA Open2023
37828025ADRA2A and IRX1 are putative risk genes for Raynaud's phenomenon.Nat Commun2023
37770476Genome-wide association studies and cross-population meta-analyses investigating short and long sleep duration.Nat Commun2023
37536152Association of comorbid-socioeconomic clusters with mortality in late onset epilepsy derived through unsupervised machine learning.Seizure2023
38028730Evaluating the impact of alternative phenotype definitions on incidence rates across a global data network.JAMIA Open2023
37393092Effect on life expectancy of temporal sequence in a multimorbidity cluster of psychosis, diabetes, and congestive heart failure among 1·7 million individuals in Wales with 20-year follow-up: a retrospective cohort study using linked data.Lancet Public Health2023
37319288Evaluation of data processing pipelines on real-world electronic health records data for the purpose of measuring patient similarity.PLoS One2023
37468884Healthcare use attributable to COVID-19: a propensity-matched national electronic health records cohort study of 249,390 people in Wales, UK.BMC Med2023
37407076Hospital admissions linked to SARS-CoV-2 infection in children and adolescents: cohort study of 3.2 million first ascertained infections in England.BMJ2023
37308303Diagnostic windows in non-neoplastic diseases: a systematic review.Br J Gen Pract2023
37306981Independent Associations of Incident Epilepsy and Enzyme-Inducing and Non-Enzyme-Inducing Antiseizure Medications With the Development of Osteoporosis.JAMA Neurol2023
37236697Identifying subtypes of heart failure from three electronic health record sources with machine learning: an external, prognostic, and genetic validation study.Lancet Digit Health2023
37034358Contextualising adverse events of special interest to characterise the baseline incidence rates in 24 million patients with COVID-19 across 26 databases: a multinational retrospective cohort study.EClinicalMedicine2023
37227368Evaluating Metformin Strategies for Cancer Prevention: A Target Trial Emulation Using Electronic Health Records.Epidemiology2023
37294923Incidence of 12 common cardiovascular diseases and subsequent mortality risk in the general population.Eur J Prev Cardiol2023
36857859Identifying subtypes of chronic kidney disease with machine learning: development, internal validation and prognostic validation using linked electronic health records in 350,067 individuals.EBioMedicine2023
36647111Harmonising electronic health records for reproducible research: challenges, solutions and recommendations from a UK-wide COVID-19 research collaboration.BMC Med Inform Decis Mak2023
36460578Identifying and visualising multimorbidity and comorbidity patterns in patients in the English National Health Service: a population-based study.Lancet Digit Health2023
36895179Determining cardiovascular risk in patients with unattributed chest pain in UK primary care: an electronic health record study.Eur J Prev Cardiol2023
36658423The impact of the COVID-19 pandemic on cardiovascular disease prevention and management.Nat Med2023
36374585Using national electronic health records for pandemic preparedness: validation of a parsimonious model for predicting excess deaths among those with COVID-19-a data-driven retrospective cohort study.J R Soc Med2023
36385522Effects of the COVID-19 pandemic on secondary care for cardiovascular disease in the UK: an electronic health record analysis across three countries.Eur Heart J Qual Care Clin Outcomes2023
36083213Translating and evaluating historic phenotyping algorithms using SNOMED CT.J Am Med Inform Assoc2023
34781301Identification and Mapping Real-World Data Sources for Heart Failure, Acute Coronary Syndrome, and Atrial Fibrillation.Cardiology2022
35653017Phenotype Algorithms for the Identification and Characterization of Vaccine-Induced Thrombotic Thrombocytopenia in Real World Data: A Multinational Network Cohort Study.Drug Saf2022
35585198Reporting guideline for the early-stage clinical evaluation of decision support systems driven by artificial intelligence: DECIDE-AI.Nat Med2022
35584845Reporting guideline for the early stage clinical evaluation of decision support systems driven by artificial intelligence: DECIDE-AI.BMJ2022
35381005Reproducible disease phenotyping at scale: Example of coronary artery disease in UK Biobank.PLoS One2022
35351727Impact of chronic kidney disease on case ascertainment for hospitalised acute myocardial infarction: an English cohort study.BMJ Open2022
35650572Adiposity and grip strength: a Mendelian randomisation study in UK Biobank.BMC Med2022
35639667Critical appraisal of artificial intelligence-based prediction models for cardiovascular disease.Eur Heart J2022
35724769A retrospective cohort study predicting and validating impact of the COVID-19 pandemic in individuals with chronic kidney disease.Kidney Int2022
35681241Elevated plasma triglyceride concentration and risk of adverse clinical outcomes in 1.5 million people: a CALIBER linked electronic health record study.Cardiovasc Diabetol2022
36476601Neural-signature methods for structured EHR prediction.BMC Med Inform Decis Mak2022
36562446CODE-EHR best practice framework for the use of structured electronic healthcare records in clinical research.BMJ2022
36150402Comparing clinical trial population representativeness to real-world populations: an external validity analysis encompassing 43â¿¿895 trials and 5â¿¿685â¿¿738 individuals across 989 unique drugs and 286 conditions in England.Lancet Healthy Longev2022
36208161CODE-EHR best practice framework for the use of structured electronic healthcare records in clinical research.Eur Heart J2022
36357675Rare and common genetic determinants of metabolic individuality and their effects on human health.Nat Med2022
36227072Transforming and evaluating the UK Biobank to the OMOP Common Data Model for COVID-19 research and beyond.J Am Med Inform Assoc2022
36121907Association of COVID-19 With Major Arterial and Venous Thrombotic Diseases: A Population-Wide Cohort Study of 48 Million Adults in England and Wales.Circulation2022
36220323Association between practice coding of chronic kidney disease (CKD) in primary care and subsequent hospitalisations and death: a cohort analysis using national audit data.BMJ Open2022
36186392Patterns of multimorbidity and some psychiatric disorders: A systematic review of the literature.Front Psychol2022
36050271CODE-EHR best-practice framework for the use of structured electronic health-care records in clinical research.Lancet Digit Health2022
35130878Lifetime risk of cardiovascular-renal disease in type 2 diabetes: a population-based study in 473,399 individuals.BMC Med2022
35317796Correction to: Lifetime risk of cardiovascular-renal disease in type 2 diabetes: a population-based study in 473,399 individuals.BMC Med2022
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Collaborators

Co-authored papers 18
Institute for Health Informatics, University College London
Co-authored papers 8
Co-authored papers 8
Institute of Psychiatry, King's College London
Co-authored papers 6
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Institute of Health Informatics, University College London
Co-authored papers 6
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University College London
Co-authored papers 4
Institute of Cancer and Genomic Sciences, University of Birmingham
Co-authored papers 4
British Heart Foundation Centre of Research Excellence, University of Glasgow
Co-authored papers 4
University of Bristol
Co-authored papers 4
Co-authored papers 3
Institute of Health Informatics, University College London
Co-authored papers 3
Thomas Jefferson University
Co-authored papers 3
Riyadh Elm University
Co-authored papers 3
University of California los angeles
Co-authored papers 3
John Radcliffe Hospital, University of Oxford
Co-authored papers 3
University of Oxford
Co-authored papers 3
Janssen Pharmaceutical Research and Development
Co-authored papers 3
Harvard University, Moorfields Eye Hospital NHS Foundation Trust, St. John's Mercy Hospital, University of British Columbia, University of Washington, Washington University in Saint Louis
Co-authored papers 3
Erasmus University Medical Center
Co-authored papers 3
Moorfields Eye Hospital NHS Foundation Trust
Co-authored papers 3
University Hospitals Birmingham NHS Foundation Trust
Co-authored papers 3
Erasmus University Medical Center
Co-authored papers 3
Moorfields Eye Hospital NHS Foundation Trust
Co-authored papers 3
Biosystematics Group Wageningen University Wageningen The Netherlands.
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Janssen Pharmaceutical Research and Development
Co-authored papers 3