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Author Details

Osvaldo Gra??a
Spanish National Cancer Research Centre-CNIO
2002
75
35
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36326833Mammalian CDC14 phosphatases control exit from stemness in pluripotent cells.EMBO J2023
36519825Pseudoalignment tools as an efficient alternative to detect repeated transposable elements in scRNAseq data.Bioinformatics2023
35174975A clinically compatible drug-screening platform based on organotypic cultures identifies vulnerabilities to prevent and treat brain metastasis.EMBO Mol Med2022
364539933D chromatin connectivity underlies replication origin efficiency in mouse embryonic stem cells.Nucleic Acids Res2022
36316722Folliculin-interacting protein FNIP2 impacts on overweight and obesity through a polymorphism in a conserved 3' untranslated region.Genome Biol2022
34260908Inhibition of Rag GTPase signaling in mice suppresses B cell responses and lymphomagenesis with minimal detrimental trade-offs.Cell Rep2021
37118410Short and dysfunctional telomeres sensitize the kidneys to develop fibrosis.Nat Aging2021
33800656MicroRNAs Possibly Involved in the Development of Bone Metastasis in Clear-Cell Renal Cell Carcinoma.Cancers (Basel)2021
34957415Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism.Nat Cancer2021
34392311NKG2D-CAR-transduced natural killer cells efficiently target multiple myeloma.Blood Cancer J2021
34239974Compi: a framework for portable and reproducible pipelines.PeerJ Comput Sci2021
34237032Deficient adaptation to centrosome duplication defects in neural progenitors causes microcephaly and subcortical heterotopias.JCI Insight2021
34205829MicroRNAs Targeting HIF-2α, VEGFR1 and/or VEGFR2 as Potential Predictive Biomarkers for VEGFR Tyrosine Kinase and HIF-2α Inhibitors in Metastatic Clear-Cell Renal Cell Carcinoma.Cancers (Basel)2021
31403184Hsa-miR-139-5p is a prognostic thyroid cancer marker involved in HNRNPF-mediated alternative splicing.Int J Cancer2020
33077955Midkine rewires the melanoma microenvironment toward a tolerogenic and immune-resistant state.Nat Med2020
32915890MicroRNA expression profiles in molecular subtypes of clear-cell renal cell carcinoma are associated with clinical outcome and repression of specific mRNA targets.PLoS One2020
32989249Global hyperactivation of enhancers stabilizes human and mouse naive pluripotency through inhibition of CDK8/19 Mediator kinases.Nat Cell Biol2020
32587399The GATA3 X308_Splice breast cancer mutation is a hormone context-dependent oncogenic driver.Oncogene2020
32614092Transient exposure to miR-203 enhances the differentiation capacity of established pluripotent stem cells.EMBO J2020
32350726Metatax: Metataxonomics with a Compi-Based Pipeline for Precision Medicine.Interdiscip Sci2020
32127537The mTOR pathway is necessary for survival of mice with short telomeres.Nat Commun2020
30914738Detection of novel fusion-transcripts by RNA-Seq in T-cell lymphoblastic lymphoma.Sci Rep2019
31410193Integrative multi-omics analysis identifies a prognostic miRNA signature and a targetable miR-21-3p/TSC2/mTOR axis in metastatic pheochromocytoma/paraganglioma.Theranostics2019
31426913TERRA regulate the transcriptional landscape of pluripotent cells through TRF1-dependent recruitment of PRC2.Elife2019
31475747Lymphatic vessels interact dynamically with the hair follicle stem cell niche during skin regeneration in vivo.EMBO J2019
30742097Downregulation of specific FBXW7 isoforms with differential effects in T-cell lymphoblastic lymphoma.Oncogene2019
30923829Chromatin regulation by Histone H4 acetylation at Lysine 16 during cell death and differentiation in the myeloid compartment.Nucleic Acids Res2019
30975481Complete Regression of Advanced Pancreatic Ductal Adenocarcinomas upon Combined Inhibition of EGFR and C-RAF.Cancer Cell2019
29211825Bicycle: a bioinformatics pipeline to analyze bisulfite sequencing data.Bioinformatics2018
29884215CREBBP/EP300 bromodomains are critical to sustain the GATA1/MYC regulatory axis in proliferation.Epigenetics Chromatin2018
29924850TWEAK increases CD74 expression and sensitizes to DDT proinflammatory actions in tubular cells.PLoS One2018
29661169RNA-Seq reveals the existence of a CDKN1C-E2F1-TP53 axis that is altered in human T-cell lymphoblastic lymphomas.BMC Cancer2018
29654229Somatic genome editing with the RCAS-TVA-CRISPR-Cas9 system for precision tumor modeling.Nat Commun2018
29320736The RNA Polymerase II Factor RPAP1 Is Critical for Mediator-Driven Transcription and Cell Identity.Cell Rep2018
29351990Saa3 is a key mediator of the protumorigenic properties of cancer-associated fibroblasts in pancreatic tumors.Proc Natl Acad Sci U S A2018
28658220Whole-body imaging of lymphovascular niches identifies pre-metastatic roles of midkine.Nature2017
28302866Genomic Profiling of Patient-Derived Xenografts for Lung Cancer Identifies <i>B2M</i> Inactivation Impairing Immunorecognition.Clin Cancer Res2017
28356389Liver carcinogenesis by FOS-dependent inflammation and cholesterol dysregulation.J Exp Med2017
28423321Hepatocellular Carcinomas Originate Predominantly from Hepatocytes and Benign Lesions from Hepatic Progenitor Cells.Cell Rep2017
28396363Genomic and Molecular Screenings Identify Different Mechanisms for Acquired Resistance to MET Inhibitors in Lung Cancer Cells.Mol Cancer Ther2017
28465321Programmed mitophagy is essential for the glycolytic switch during cell differentiation.EMBO J2017
29269732Systems analysis identifies melanoma-enriched pro-oncogenic networks controlled by the RNA binding protein CELF1.Nat Commun2017
28827401Inactivation of Capicua in adult mice causes T-cell lymphoblastic lymphoma.Genes Dev2017
27089206Chronic skin inflammation leads to bone loss by IL-17-mediated inhibition of Wnt signaling in osteoblasts.Sci Transl Med2016
27699216Deep sequencing reveals microRNAs predictive of antiangiogenic drug response.JCI Insight2016
27604143NSD2 contributes to oncogenic RAS-driven transcription in lung cancer cells through long-range epigenetic activation.Sci Rep2016
27857118Lineage-specific roles of the cytoplasmic polyadenylation factor CPEB4 in the regulation of melanoma drivers.Nat Commun2016
27531349Telomeric RNAs are essential to maintain telomeres.Nat Commun2016
25788273Nuclear DICKKOPF-1 as a biomarker of chemoresistance and poor clinical outcome in colorectal cancer.Oncotarget2015
26365176MYC/PGC-1α Balance Determines the Metabolic Phenotype and Plasticity of Pancreatic Cancer Stem Cells.Cell Metab2015
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Collaborators

Alfonso Valencia
Josep Carreras Leukaemia Research Institute (IJC)
Co-authored papers 13
F??tima Al-Shahrour
Spanish National Cancer Research Centre (CNIO)
Co-authored papers 8
Michael L Tress
Spanish National Cancer Research Centre (CNIO)
Co-authored papers 6
Cristina Rodr??guez-Antona
Spanish National Cancer Research Center (CNIO)
Co-authored papers 6
Burkhard Rost
Technical University of Munich (TUM)
Co-authored papers 4
Florencio Pazos
National Centre for Biotechnology (CNB-CSIC)
Co-authored papers 4
Volker A Eyrich
Columbia University
Co-authored papers 3
Raul Rabadan
Columbia University Vagelos College of Physicians and Surgeons
Co-authored papers 3
Eva P??rez-Guijarro
National Cancer Institute, National Institutes of Health (NIH)
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Gonzalo L??pez
Children's Hospital of Philadelphia
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Mitchell P Levesque
University Hospital Zurich
Co-authored papers 2
Dariusz Przybylski
Howard Hughes Medical Institute, Brandeis University
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Ram??n Campos-Olivas
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Co-authored papers 2
Jes??s Garc??a-Donas
HM Hospitales-Centro Integral Oncologico Clara Campal
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Eduardo Eyras
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Ingrid Y Y Koh
Columbia University Center for Computational Biology and Bioinformatics (C2B2)
Co-authored papers 2
Francisco X Real
Spanish National Cancer Research Centre-CNIO
Co-authored papers 2
Carlos Caldas
Cancer Research UK Cambridge Institute, University of Cambridge
Co-authored papers 1
Marc Dabad
Universitat de Barcelona (UB)
Co-authored papers 1
Vera Pancaldi
Universite de Toulouse, Inserm, CNRS, Universite Toulouse III-Paul Sabatier
Co-authored papers 1
Carlos L??pez-Ot??n
Instituto Universitario de Oncologia, Universidad de Oviedo
Co-authored papers 1
Jaume Mora
Pediatric Cancer Center Barcelona, Hospital Sant Joan de Deu
Co-authored papers 1
Nuria Montserrat
Catalan Institution for Research and Advanced Studies (ICREA)
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Jose Javier Bravo-Cordero
The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai
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Rita Casadio
Department of Pharmacy and Biotechnology, University of Bologna
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Release 1.2