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Author Details

Bruce A Hamilton
1990
67
30
PMIDPaper TitleJournal TitlePublished Year
35100349Ankfn1-mutant vestibular defects require loss of both ancestral and derived paralogs for penetrance in zebrafish.G3 (Bethesda)2022
32967895Strain-Dependent Modifier Genes Determine Survival in Mice.G3: Genes, Genomes, Genetics2020
31943697The lipid elongation enzyme ELOVL2 is a molecular regulator of aging in the retina.Aging Cell2020
32925911ZNF423 patient variants, truncations, and in-frame deletions in mice define an allele-dependent range of midline brain abnormalities.PLoS Genetics2020
29305158TBR2 antagonizes retinoic acid dependent neuronal differentiation by repressing Zfp423 during corticogenesis.Developmental Biology2018
28059714Regeneration of fat cells from myofibroblasts during wound healing.Science2017
28011710Identification of novel loci affecting circulating chromogranins and related peptides.Hum Mol Genet2017
27814941Deleting an Nr4a1 Super-Enhancer Subdomain Ablates Ly6C<sup>low</sup> Monocytes while Preserving Macrophage Gene Function.Immunity2016
27977693Deep Reads: Favorites from a Few Different Shelves.PLoS Genetics2016
27727273Zfp423 Regulates Sonic Hedgehog Signaling via Primary Cilium Function.PLoS Genetics2016
26131556Nmf9 Encodes a Highly Conserved Protein Important to Neurological Function in Mice and Flies.PLoS Genetics2015
25835743Nxf1 natural variant E610G is a semi-dominant suppressor of IAP-induced RNA processing defects.PLoS Genet2015
23468657Retrotransposon activates ectopic Ptf1 expression: a short tail.PLoS Genetics2013
23762491Zfp423 binds autoregulatory sites in p19 cell culture model.PLoS ONE2013
21918574Genetic variation within a metabolic motif in the chromogranin a promoter: pleiotropic influence on cardiometabolic risk traits in twins.Am J Hypertens2012
22511884Modifier genes and the plasticity of genetic networks in mice.PLoS Genetics2012
22863007Exome capture reveals ZNF423 and CEP164 mutations, linking renal ciliopathies to DNA damage response signaling.Cell2012
22172665Tracking intron removal in real time.Developmental Cell2011
21104344Catecholamine storage vesicles: role of core protein genetic polymorphisms in hypertension.Curr Hypertens Rep2011
21321132Modifier genes for mouse phosphatidylinositol transfer protein α (vibrator) that bypass juvenile lethality.Genetics2011
20814407Human dopamine β-hydroxylase promoter variant alters transcription in chromaffin cells, enzyme secretion, and blood pressure.Am J Hypertens2011
21729880Modifier genes and non-genetic factors reshape anatomical deficits in Zfp423-deficient mice.Human Molecular Genetics2011
20204374Conserved regulatory motifs at phenylethanolamine N-methyltransferase (PNMT) are disrupted by common functional genetic variation: an integrated computational/experimental approach.Mamm Genome2010
21061160Naturally occurring genetic variants in human chromogranin A (CHGA) associated with hypertension as well as hypertensive renal disease.Cell Mol Neurobiol2010
20861615Common charge-shift mutation Glu65Lys in K+ channel β⿁-Subunit KCNMB1: pleiotropic consequences for glomerular filtration rate and progressive renal disease.Am J Nephrol2010
19903454Letter to the editor on "Threonine 53 in alpha-synuclein is conserved in long-living non-primate animals".Biochemical and Biophysical Research Communications2010
20009769Human dopamine beta-hydroxylase (DBH) regulatory polymorphism that influences enzymatic activity, autonomic function, and blood pressure.J Hypertens2010
19820027Peptide YY (PYY) gene polymorphisms in the 3'-untranslated and proximal promoter regions regulate cellular gene expression and PYY secretion and metabolic syndrome traits in vivo.J Clin Endocrinol Metab2009
28199513Peptide YY (PYY) Gene Polymorphisms in the 3'-Untranslated Region and Proximal Promoter Regions Regulate Cellular Gene Expression and PYY Secretion and Metabolic Syndrome Traits in Vivo.Endocr Rev2009
19436707Multipotent genetic suppression of retrotransposon-induced mutations by Nxf1 through fine-tuning of alternative splicing.PLoS Genetics2009
19712806Neuropeptide Y(1) Receptor NPY1R discovery of naturally occurring human genetic variants governing gene expression in cella as well as pleiotropic effects on autonomic activity and blood pressure in vivo.J Am Coll Cardiol2009
19520754Chromogranin A regulates renal function by triggering Weibel-Palade body exocytosis.J Am Soc Nephrol2009
18235090Chromogranin A polymorphisms are associated with hypertensive renal disease.J Am Soc Nephrol2008
19017515Naturally occurring human genetic variation in the 3'-untranslated region of the secretory protein chromogranin A is associated with autonomic blood pressure regulation and hypertension in a sex-dependent fashion.J Am Coll Cardiol2008
18432188Common genetic variants in the chromogranin A promoter alter autonomic activity and blood pressure.Kidney Int2008
16427031ROR alpha in genetic control of cerebellum development: 50 staggering years.Brain Research2007
17211240C-reactive protein, an 'intermediate phenotype' for inflammation: human twin studies reveal heritability, association with blood pressure and the metabolic syndrome, and the influence of common polymorphism at catecholaminergic/beta-adrenergic pathway loci.J Hypertens2007
17584765An ancestral variant of Secretogranin II confers regulation by PHOX2 transcription factors and association with hypertension.Hum Mol Genet2007
17353515Renal albumin excretion: twin studies identify influences of heredity, environment, and adrenergic pathway polymorphism.Hypertension2007
17440933Interaction between the ADAM12 and SH3MD1 genes may confer susceptibility to late-onset Alzheimer's disease.Am J Med Genet B Neuropsychiatr Genet2007
17438154Catecholamine release-inhibitory peptide catestatin (chromogranin A(352-372)): naturally occurring amino acid variant Gly364Ser causes profound changes in human autonomic activity and alters risk for hypertension.Circulation2007
16648942Analyses of 5' regulatory region polymorphisms in human SLC22A6 (OAT1) and SLC22A8 (OAT3).J Hum Genet2006
17151198Zfp423 controls proliferation and differentiation of neural precursors in cerebellar vermis formation.Proceedings of the National Academy of Sciences of the United States of America2006
17026486Catecholamine storage vesicles and the metabolic syndrome: The role of the chromogranin A fragment pancreastatin.Diabetes Obes Metab2006
16164626Analyses of coding region polymorphisms in apical and basolateral human organic anion transporter (OAT) genes [OAT1 (NKT), OAT2, OAT3, OAT4, URAT (RST)].Kidney Int2005
14740315Both rare and common polymorphisms contribute functional variation at CHGA, a regulator of catecholamine physiology.Am J Hum Genet2004
15326220The catecholamine release-inhibitory "catestatin" fragment of chromogranin a: naturally occurring human variants with different potencies for multiple chromaffin cell nicotinic cholinergic responses.Mol Pharmacol2004
15514066Mutation rate and predicted phenotypic target sizes in ethylnitrosourea-treated mice.Genetics2004
15028296alpha-Synuclein A53T substitution associated with Parkinson disease also marks the divergence of Old World and New World primates.Genomics2004
14687547RORalpha coordinates reciprocal signaling in cerebellar development through sonic hedgehog and calcium-dependent pathways.Neuron2003
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