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Author Details

Darren L Roberts
The University of Manchester
2001
21
14
PMIDPaper TitleJournal TitlePublished Year
35707756Feasibility of a multiparametric MRI protocol for imaging biomarkers associated with neoadjuvant radiotherapy for soft tissue sarcoma.BJR Open2021
33385074Sarcopenia in cancer: Risking more than muscle loss.Tech Innov Patient Support Radiat Oncol2020
29235571The hypoxia marker CAIX is prognostic in the UK phase III VorteX-Biobank cohort: an important resource for translational research in soft tissue sarcoma.Br J Cancer2018
29729848Development and Validation of a 28-gene Hypoxia-related Prognostic Signature for Localized Prostate Cancer.EBioMedicine2018
28122336Distinct patterns of infiltrating CD8+ T cells in HPV+ and CD68 macrophages in HPV- oropharyngeal squamous cell carcinomas are associated with better clinical outcome but PD-L1 expression is not prognostic.Oncotarget2017
26026165A framework for the in vitro evaluation of cancer-relevant molecular characteristics and mitogenic potency of insulin analogues.Carcinogenesis2015
25929336Global gene expression in pseudomyxoma peritonei, with parallel development of two immortalized cell lines.Oncotarget2015
23798369Noninvasive tumor hypoxia measurement using magnetic resonance imaging in murine U87 glioma xenografts and in patients with glioblastoma.Magn Reson Med2014
24068609Chronic insulin exposure does not cause insulin resistance but is associated with chemo-resistance in colon cancer cells.Horm Metab Res2014
20549702The development of composite circulating biomarker models for use in anticancer drug clinical development.Int J Cancer2011
21939458Effect of prolonged formalin fixation on immunohistochemical staining for the proliferation marker Ki67.Histopathology2011
21393866Hypoxic human cancer cells are sensitized to BH-3 mimeticâ¿¿induced apoptosis via downregulation of the Bcl-2 protein Mcl-1.J Clin Invest2011
19824817Biological mechanisms linking obesity and cancer risk: new perspectives.Annu Rev Med2010
19718054Reactivating HIF prolyl hydroxylases under hypoxia results in metabolic catastrophe and cell death.Oncogene2009
19755992Contribution of HIF-1 and drug penetrance to oxaliplatin resistance in hypoxic colorectal cancer cells.Br J Cancer2009
18648372Reciprocal relationship between expression of hypoxia inducible factor 1alpha (HIF-1alpha) and the pro-apoptotic protein bid in ex vivo colorectal cancer.Br J Cancer2008
18465361Obesity and cancer: pathophysiological and biological mechanisms.Arch Physiol Biochem2008
12729586Mitochondria at the heart of the cytotoxic attack.Biochem Biophys Res Commun2003
12648453Granzyme B-induced apoptosis requires both direct caspase activation and relief of caspase inhibition.Immunity2003
11550094Caspase-3 cleaves Apaf-1 into an approximately 30 kDa fragment that associates with an inappropriately oligomerized and biologically inactive approximately 1.4 MDa apoptosome complex.Cell Death Differ2001
11285287The inhibitor of apoptosis protein-binding domain of Smac is not essential for its proapoptotic activity.J Cell Biol2001
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Collaborators

Ananya Choudhury
University of Manchester and The Christie NHS Foundation Trust
Co-authored papers 4
Catharine M L West
University of Manchester
Co-authored papers 3
Peter Hoskin
Mount Vernon Cancer Centre
Co-authored papers 2
David E Neal
University of Oxford, John Radcliffe Hospital
Co-authored papers 1
Vinayak Bhandari
University of Toronto
Co-authored papers 1
Darragh G McArt
Queen's University Belfast
Co-authored papers 1
Mohammed Alshalalfa
University of Miami Miller School of Medicine/Sylvester Comprehensive Cancer Center
Co-authored papers 1
Robert G Bristow
University of Toronto
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R Jeffrey Karnes
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Co-authored papers 1
Suneil Jain
Cancer Centre Belfast City Hospital, Queen's University Belfast
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Syed Haider
Institute of Cancer Research
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Ashley E Ross
Northwestern University
Co-authored papers 1
Edward Schaffer
Northwestern Feinberg School of Medicine
Co-authored papers 1
Paul C Boutros
University of California los angeles
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Lingjian Yang
Ankang University
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GenomeDx Biosciences Inc.
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Niluja Thiruthaneeswaran
The University of Sydney, Westmead Hospital
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Stephen J Freedland
Cedars-Sinai Medical Center
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Becky A S Bibby
University of Manchester, Christie Hospital
Co-authored papers 1
Nicholas Erho
GenomeDx Biosciences Inc.
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Wei-Chen Cheng
MRC Oxford Institute for Radiation Oncology & Biology, University of Oxford
Co-authored papers 1
Elai Davicioni
Veracyte Inc.
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Fiona Blackhall
The University of Manchester
Co-authored papers 1
Christopher Cawthorne
Co-authored papers 1
Amy M B McCorry
Queen's University Belfast
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Robert B Den
Thomas Jefferson University Hospital
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Alastair D Lamb
University of Oxford
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Eric A Klein
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Francesca M Buffa
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Release 1.2