Author details

Full Name

Colin Kleanthous

Affiliation

ORCID

Career Start Year

1984

Papers

177

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37399084	Outer membrane translocation of pyocins via the copper regulated TonB-dependent transporter CrtA.		2023
37558670	Antibiotics and hexagonal order in the bacterial outer membrane.		2023
35343790	Bacterial Competition Systems Share a Domain Required for Inner Membrane Transport of the Bacteriocin Pyocin G from Pseudomonas aeruginosa.	mBio	2022
35705811	Peptidoglycan maturation controls outer membrane protein assembly.	Nature	2022
36322653	Lipids mediate supramolecular outer membrane protein assembly in bacteria.	Sci Adv	2022
35308353	Force-Generation by the Trans-Envelope Tol-Pal System.	Frontiers in Microbiology	2022
34544275	Colicin-Mediated Transport of DNA through the Iron Transporter FepA.	mBio	2021
34142136	Pyocin efficacy in a murine model of Pseudomonas aeruginosa sepsis.	Journal of Antimicrobial Chemotherapy	2021
34330923	Toxin import through the antibiotic efflux channel TolC.	Nat Commun	2021
34515361	Porin threading drives receptor disengagement and establishes active colicin transport through Escherichia coli OmpF.	EMBO Journal	2021
34965245	The quantitative basis for the redistribution of immobile bacterial lipoproteins to division septa.	PLoS Computational Biology	2021
34716276	Phase separation in the outer membrane of .	Proceedings of the National Academy of Sciences of the United States of America	2021
32614588	Transmembrane Epitope Delivery by Passive Protein Threading through the Pores of the OmpF Porin Trimer.	Journal of the American Chemical Society	2020
32398259	Bifurcated binding of the OmpF receptor underpins import of the bacteriocin colicin N into Escherichia coli.	J Biol Chem	2020
32339530	Targeted Killing of Pseudomonas aeruginosa by Pyocin G Occurs via the Hemin Transporter Hur.	Journal of Molecular Biology	2020
32161270	The lipoprotein Pal stabilises the bacterial outer membrane during constriction by a mobilisation-and-capture mechanism.	Nature Communications	2020
32156826	Pyocin S5 Import into Pseudomonas aeruginosa Reveals a Generic Mode of Bacteriocin Transport.	mBio	2020
32472934	The multifarious roles of Tol-Pal in Gram-negative bacteria.	FEMS Microbiology Reviews	2020
32513855	Genomic Profiling Reveals Distinct Routes To Complement Resistance in Klebsiella pneumoniae.	Infection and Immunity	2020
31001227	Tools and Approaches for Dissecting Protein Bacteriocin Import in Gram-Negative Bacteria.	Frontiers in Microbiology	2019
30510143	O-Antigen-Dependent Colicin Insensitivity of Uropathogenic Escherichia coli.	Journal of Bacteriology	2019
29540681	Intermembrane crosstalk drives inner-membrane protein organization in Escherichia coli.	Nature Communications	2018
30030429	How nanoscale protein interactions determine the mesoscale dynamic organisation of bacterial outer membrane proteins.	Nature Communications	2018
29891712	Lipid binding attenuates channel closure of the outer membrane protein OmpF.	Proc Natl Acad Sci U S A	2018
30206118	The CcmC-CcmE interaction during cytochrome maturation by System I is driven by protein-protein and not protein-heme contacts.	Journal of Biological Chemistry	2018
30538236	Ultrahigh specificity in a network of computationally designed protein-interaction pairs.	Nat Commun	2018
30137977	Correction to "Directional Porin Binding of Intrinsically Disordered Protein Sequences Promotes Colicin Epitope Display in the Bacterial Periplasm".	Biochemistry	2018
29949342	Directional Porin Binding of Intrinsically Disordered Protein Sequences Promotes Colicin Epitope Display in the Bacterial Periplasm.	Biochemistry	2018
30323216	Compartmentalizing acid stress in bacteria.	Nature Chemical Biology	2018
29540701	Structures of Teneurin adhesion receptors reveal an ancient fold for cell-cell interaction.	Nature Communications	2018
28094462	Orientation of the OmpF Porin in Planar Lipid Bilayers.	ChemBioChem	2017
33525816	The therapeutic potential of bacteriocins as protein antibiotics.	Emerging topics in life sciences	2017
33525809	Exploring emerging topics.	Emerging topics in life sciences	2017
28960650	Carbene Footprinting Reveals Binding Interfaces of a Multimeric Membrane-Spanning Protein.	Angew Chem Int Ed Engl	2017
28715501	Diversity and distribution of nuclease bacteriocins in bacterial genomes revealed using Hidden Markov Models.	PLoS Comput Biol	2017
28884954	Native Desorption Electrospray Ionization Liberates Soluble and Membrane Protein Complexes from Surfaces.	Angew Chem Int Ed Engl	2017
29078392	Exploitation of an iron transporter for bacterial protein antibiotic import.	Proceedings of the National Academy of Sciences of the United States of America	2017
27252387	Discovery, characterization and inÂ vivo activity of pyocin SD2, a protein antibiotic from Pseudomonas aeruginosa.	Biochemical Journal	2016
27432510	The anti-sigma factor RsrA responds to oxidative stress by reburying its hydrophobic core.	Nat Commun	2016
27402794	Structural and biophysical analysis of nuclease protein antibiotics.	Biochemical Journal	2016
26901650	High-resolution mass spectrometry of small molecules bound to membrane proteins.	Nat Methods	2016
26061769	Supramolecular assemblies underpin turnover of outer membrane proteins in bacteria.	Nature	2015
25856265	Consequences of inducing intrinsic disorder in a high-affinity protein-protein interaction.	Journal of the American Chemical Society	2015
26354441	Structure and function of the Escherichia coli Tol-Pal stator protein TolR.	J Biol Chem	2015
26215615	Structures of the Ultra-High-Affinity Protein-Protein Complexes of Pyocins S2 and AP41 and Their Cognate Immunity Proteins from Pseudomonas aeruginosa.	Journal of Molecular Biology	2015
26629934	Protein-protein interactions and the spatiotemporal dynamics of bacterial outer membrane proteins.	Current Opinion in Structural Biology	2015
26370932	The bacterial cell envelope.	Philosophical Transactions of the Royal Society B: Biological Sciences	2015
24155158	Blind prediction of interfacial water positions in CAPRI.	Proteins	2014
23431269	A force-activated trip switch triggers rapid dissociation of a colicin from its immunity protein.	PLoS Biology	2013
24039240	Immunity protein release from a cell-bound nuclease colicin complex requires global conformational rearrangement.	MicrobiologyOpen	2013