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Author Details

Alexander P Golovanov
The University of Manchester
1991
70
22
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36257338Insights into the Stabilization of Interferon Alpha by Two Surfactants Revealed by STD-NMR Spectroscopy.J Pharm Sci2023
37146162Chemometrics in Protein Formulation: Stability Governed by Repulsion and Protein Unfolding.Mol Pharm2023
36205575Controlled release and characterisation of photocaged molecules using <i>in situ</i> LED illumination in solution NMR spectroscopy.Chem Commun (Camb)2022
35365630Temporal and spatial characterisation of protein liquid-liquid phase separation using NMR spectroscopy.Nat Commun2022
36697806Sample illumination device facilitates in situ light-coupled NMR spectroscopy without fibre optics.Commun Chem2022
36272656Lipopolysaccharide Structure and the Phenomenon of Low Endotoxin Recovery.Eur J Pharm Biopharm2022
33137420Development of a fast screening method for selecting excipients in formulations using MD simulations, NMR and microscale thermophoresis.Eur J Pharm Biopharm2021
34225583Stability of a high-concentration monoclonal antibody solution produced by liquid-liquid phase separation.MAbs2021
32283214Binding of excipients is a poor predictor for aggregation kinetics of biopharmaceutical proteins.Eur J Pharm Biopharm2020
33659867Comprehensive Assessment of Protein and Excipient Stability in Biopharmaceutical Formulations Using <sup>1</sup>H NMR Spectroscopy.ACS Pharmacol Transl Sci2020
31689429Orthogonal Techniques to Study the Effect of pH, Sucrose, and Arginine Salts on Monoclonal Antibody Physical Stability and Aggregation During Long-Term Storage.J Pharm Sci2020
32609526The Effect of Point Mutations on the Biophysical Properties of an Antimicrobial Peptide: Development of a Screening Protocol for Peptide Stability Screening.Mol Pharm2020
30601476Detection of the adulteration of fresh coconut water via NMR spectroscopy and chemometrics.Analyst2019
31641093Molecular Mechanism of SR Protein Kinase 1 Inhibition by the Herpes Virus Protein ICP27.mBio2019
31720525New Disulphide Bond in Cystatin-Based Protein Scaffold Prevents Domain-Swap-Mediated Oligomerization and Stabilizes the Functionally Active Form.ACS Omega2019
31943902Use of <sup>19</sup> F Differential Labelling for the Simultaneous Detection and Monitoring of Three Individual Proteins in a Serum Environment.Chempluschem2019
31314511Arginine to Lysine Mutations Increase the Aggregation Stability of a Single-Chain Variable Fragment through Unfolded-State Interactions.Biochemistry2019
31227800Studies of the oligomerisation mechanism of a cystatin-based engineered protein scaffold.Sci Rep2019
31099578Conformational Stability Study of a Therapeutic Peptide Plectasin Using Molecular Dynamics Simulations in Combination with NMR.J Phys Chem B2019
30801173<sup>19</sup>F Dark-State Exchange Saturation Transfer NMR Reveals Reversible Formation of Protein-Specific Large Clusters in High-Concentration Protein Mixtures.Anal Chem2019
31088082Interaction of a Macrocycle with an Aggregation-Prone Region of a Monoclonal Antibody.Mol Pharm2019
30462297Structural identification of conserved RNA binding sites in herpesvirus ORF57 homologs: implications for PAN RNA recognition.Nucleic Acids Res2019
30301920Overlapping motifs on the herpes viral proteins ICP27 and ORF57 mediate interactions with the mRNA export adaptors ALYREF and UIF.Sci Rep2018
29863878<sup>19</sup>F NMR as a Tool for Monitoring Individual Differentially Labeled Proteins in Complex Mixtures.Mol Pharm2018
29921674The ICP27 Homology Domain of the Human Cytomegalovirus Protein UL69 Adopts a Dimer-of-Dimers Structure.mBio2018
28614662Investigating Liquid-Liquid Phase Separation of a Monoclonal Antibody Using Solution-State NMR Spectroscopy: Effect of Arg·Glu and Arg·HCl.Mol Pharm2017
28161552The effect of charge mutations on the stability and aggregation of a human single chain Fv fragment.Eur J Pharm Biopharm2017
28505309The herpes viral transcription factor ICP4 forms a novel DNA recognition complex.Nucleic Acids Res2017
27113141Graphene in therapeutics delivery: Problems, solutions and future opportunities.Eur J Pharm Biopharm2016
26565026Monitoring Ras Interactions with the Nucleotide Exchange Factor Son of Sevenless (Sos) Using Site-specific NMR Reporter Signals and Intrinsic Fluorescence.J Biol Chem2016
27589351Characterizing monoclonal antibody formulations in arginine glutamate solutions using <sup>1</sup>H NMR spectroscopy.MAbs2016
27412770Dynamic studies of H-Ras⿢GTPγS interactions with nucleotide exchange factor Sos reveal a transient ternary complex formation in solution.Sci Rep2016
26873863The effects of arginine glutamate, a promising excipient for protein formulation, on cell viability: Comparisons with NaCl.Toxicol In Vitro2016
26062451The structure of the folded domain from the signature multifunctional protein ICP27 from herpes simplex virus-1 reveals an intertwined dimer.Sci Rep2015
24550725Competitive and cooperative interactions mediate RNA transfer from herpesvirus saimiri ORF57 to the mammalian export adaptor ALYREF.PLoS Pathog2014
24992318The effect of arginine glutamate on the stability of monoclonal antibodies in solution.Int J Pharm2014
22886485¹H, ¹³C and ¹⁵N resonance assignment for the human K-Ras at physiological pH.Biomol NMR Assign2013
23637401The interaction of the cellular export adaptor protein Aly/REF with ICP27 contributes to the efficiency of herpes simplex virus 1 mRNA export.J Virol2013
22729179Fingerprinting food: current technologies for the detection of food adulteration and contamination.Chem Soc Rev2012
22955930In support of the BMRB.Nat Struct Mol Biol2012
21253573Structural basis for the recognition of cellular mRNA export factor REF by herpes viral proteins HSV-1 ICP27 and HVS ORF57.PLoS Pathog2011
19485366Simultaneous measurement of residual dipolar couplings for proteins in complex using the isotopically discriminated NMR approach.J Am Chem Soc2009
18364396Mutually exclusive interactions drive handover of mRNA from export adaptors to TAP.Proc Natl Acad Sci U S A2008
18207440Increasing the sensitivity of cryoprobe protein NMR experiments by using the sole low-conductivity arginine glutamate salt.J Magn Reson2008
17458964Isotopically discriminated NMR spectroscopy: a tool for investigating complex protein interactions in vitro.J Am Chem Soc2007
17893810Quantification of casein phosphorylation with conformational interpretation using Raman spectroscopy.Analyst2007
17656366Specificity and autoregulation of Notch binding by tandem WW domains in suppressor of Deltex.J Biol Chem2007
16933020Assignment of 1H, 13C, and 15N resonances for the PilP pilot protein from Neisseria meningitidis.J Biomol NMR2006
17007878The solution structure of a domain from the Neisseria meningitidis lipoprotein PilP reveals a new beta-sandwich fold.J Mol Biol2006
17036044Molecular basis of RNA recognition and TAP binding by the SR proteins SRp20 and 9G8.EMBO J2006
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Collaborators

Lu-Yun Lian
Institute of Systems, The University of Liverpool
Co-authored papers 15
Guillaume M Hautbergue
Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield
Co-authored papers 8
Igor L Barsukov
Institute of Integrative Biology, University of Liverpool
Co-authored papers 5
Gordon C K Roberts
Leicester Institute of Structural and Chemical Biology, University of Leicester
Co-authored papers 4
Royston Goodacre
Institute of Systems, University of Liverpool
Co-authored papers 3
Navratna Vajpai
Biocon Research Limited - SEZ Unit
Co-authored papers 2
Andrej Sali (CM4AI)
University of California San Francisco
Co-authored papers 1
Walter J Chazin
and Center for Structural Biology, Vanderbilt University
Co-authored papers 1
Bernd Reif
Technische Universitat Munchen (TUM)
Co-authored papers 1
Matthew P Crump
University of Bristol
Co-authored papers 1
David A Case
Rutgers University
Co-authored papers 1
Oliver F Lange
Center for Integrated Protein Science, Technische Universitat Munchen
Co-authored papers 1
Josep Rizo
University of Texas Southwestern Medical Center
Co-authored papers 1
Mike P Williamson
The University of Sheffield
Co-authored papers 1
David E Shaw
Columbia University
Co-authored papers 1
Ad Bax
National Institutes of Health
Co-authored papers 1
Patrick C A van der Wel
Zernike Institute for Advanced Materials, University of Groningen
Co-authored papers 1
David Middleton
Co-authored papers 1
Ioannis Vakonakis
University of Oxford
Co-authored papers 1
Thomas A Frenkiel
The Medical Research Council Biomedical NMR Centre, The Francis Crick Institute
Co-authored papers 1
Ernest D Laue
University of Cambridge
Co-authored papers 1
Gordon S Rule
Carnegie Mellon University
Co-authored papers 1
Stephen Matthews
Imperial College London
Co-authored papers 1
Chien Ho
Carnegie Mellon University
Co-authored papers 1
Toshimichi Fujiwara
Institute for Protein Research, Osaka University
Co-authored papers 1
Pei Tang
Sichuan University
Co-authored papers 1
Joern Werner
Co-authored papers 1
Paul C Driscoll
The Francis Crick Institute
Co-authored papers 1
Shigeyuki Yokoyama
Shinshu University School of Medicine
Co-authored papers 1
Roberto R Gil
Carnegie Mellon University
Co-authored papers 1
Release 1.2