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Author Details

Arnold J Levine
Simons Center for Systems Biology, Institute for Advanced Study
1967
475
142
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36182991Long-term p21 and p53 dynamics regulate the frequency of mitosis events and cell cycle arrest following radiation damage.Cell Death Differ2023
36945436Accurate modeling of peptide-MHC structures with AlphaFold.bioRxiv2023
35110395Targeting the P53 Protein for Cancer Therapies: The Translational Impact of P53 Research.Cancer Res2022
35383292The genotypes and phenotypes of missense mutations in the proline domain of the p53 protein.Cell Death Differ2022
35383291Exploring the future of research in the Tp53 field.Cell Death Differ2022
35545680Fundamental immune-oncogenicity trade-offs define driver mutation fitness.Nature2022
35641605Author Correction: Fundamental immune-oncogenicity trade-offs define driver mutation fitness.Nature2022
33942515Bispecific antibodies come to the aid of cancer immunotherapy.Mol Oncol2021
34819508Geometric network analysis provides prognostic information in patients with high grade serous carcinoma of the ovary treated with immune checkpoint inhibitors.NPJ Genom Med2021
34389799Spontaneous and inherited TP53 genetic alterations.Oncogene2021
31160716Two well-differentiated pancreatic neuroendocrine tumor mouse models.Cell Death Differ2020
31952115P53 and The Immune Response: 40 Years of Exploration-A Plan for the Future.Int J Mol Sci2020
33376133Genetic and stochastic influences upon tumor formation and tumor types in Li-Fraumeni mouse models.Life Sci Alliance2020
33354623Non-Random Selection of Cancer-Causing Mutations in Tissue-Specific Stem Cells Cause Cancer.J Clin Oncol Res2020
32601217Functional network analysis reveals an immune tolerance mechanism in cancer.Proc Natl Acad Sci U S A2020
32732999Identification of relevant genetic alterations in cancer using topological data analysis.Nat Commun2020
32335977Mdm2: Open questions.Cancer Sci2020
32404993p53: 800 million years of evolution and 40 years of discovery.Nat Rev Cancer2020
30645969The Roles of Initiating Truncal Mutations in Human Cancers: The Order of Mutations and Tumor Cell Type Matters.Cancer Cell2019
31531391Robust and interpretable PAM50 reclassification exhibits survival advantage for myoepithelial and immune phenotypes.NPJ Breast Cancer2019
30925588The many faces of p53: something for everyone.J Mol Cell Biol2019
29099487Why are there hotspot mutations in the TP53 gene in human cancers?Cell Death Differ2018
29599906Dynamic changes during the treatment of pancreatic cancer.Oncotarget2018
29227987Reviewing the future of the P53 field.Cell Death Differ2018
27091942Structural Evolution and Dynamics of the p53 Proteins.Cold Spring Harb Perspect Med2017
28196891Insights into immune system development and function from mouse T-cell repertoires.Proc Natl Acad Sci U S A2017
28129641The p53 protein plays a central role in the mechanism of action of epigentic drugs that alter the methylation of cytosine residues in DNA.Oncotarget2017
28349284The Evolution of Tumor Formation in Humans and Mice with Inherited Mutations in the p53 Gene.Curr Top Microbiol Immunol2017
28267733US immigration order strikes against biotech.Nat Biotechnol2017
29132146Identification of unique neoantigen qualities in long-term survivors of pancreatic cancer.Nature2017
29132144A neoantigen fitness model predicts tumour response to checkpoint blockade immunotherapy.Nature2017
28765161The interplay between epigenetic changes and the p53 protein in stem cells.Genes Dev2017
27105526Sexual dimorphism of liver metastasis by murine pancreatic neuroendocrine tumors is affected by expression of complement C5.Oncotarget2016
26464433DTIE, a novel core promoter element that directs start site selection in TATA-less genes.Nucleic Acids Res2016
26477317The p53 tetramer shows an induced-fit interaction of the C-terminal domain with the DNA-binding domain.Oncogene2016
27535933Lysine methylation represses p53 activity in teratocarcinoma cancer cells.Proc Natl Acad Sci U S A2016
27506378Rethinking the Regulatory Infrastructure for Human Gene Transfer Clinical Trials.Mol Ther2016
27477875Corrigendum to "Reactivating mutant p53 using small molecules as zinc metallochaperones: awakening a sleeping giant in cancer" [Drug Discov. Today 20 (11) (2015) 1391-1397].Drug Discov Today2016
27172878P53 and the defenses against genome instability caused by transposons and repetitive elements.Bioessays2016
27532298Inference of Ancestral Recombination Graphs through Topological Data Analysis.PLoS Comput Biol2016
27352800The Role of the p53 Protein in Stem-Cell Biology and Epigenetic Regulation.Cold Spring Harb Perspect Med2016
27345159Topological Data Analysis Generates High-Resolution, Genome-wide Maps of Human Recombination.Cell Syst2016
25535359TAp73 opposes tumor angiogenesis by promoting hypoxia-inducible factor 1α degradation.Proc Natl Acad Sci U S A2015
26575629Distinguishing the immunostimulatory properties of noncoding RNAs expressed in cancer cells.Proc Natl Acad Sci U S A2015
26642854The Evolution of Tumors in Mice and Humans with Germline p53 Mutations.Cold Spring Harb Symp Quant Biol2015
26186894Stem cells, aging and cancers.Aging (Albany NY)2015
26205328Reactivating mutant p53 using small molecules as zinc metallochaperones: awakening a sleeping giant in cancer.Drug Discov Today2015
26145175MicroRNA-101 Suppresses Tumor Cell Proliferation by Acting as an Endogenous Proteasome Inhibitor via Targeting the Proteasome Assembly Factor POMP.Mol Cell2015
25822339Involvement of tumor suppressors PTEN and p53 in the formation of multiple subtypes of liposarcoma.Cell Death Differ2015
23583620Dipeptide analysis of p53 mutations and evolution of p53 family proteins.Biochim Biophys Acta2014
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Collaborators

Wenwei Hu
Co-authored papers 31
Raul Rabadan
Columbia University Vagelos College of Physicians and Surgeons
Co-authored papers 14
Benjamin D Greenbaum
Memorial Sloan Kettering Cancer Center
Co-authored papers 13
Peter Sarnow
Stanford University School of Medicine
Co-authored papers 9
Shengkan Jin
Robert Wood Johnson Medical School
Co-authored papers 9
Gabriela Alexe
Dana-Farber Cancer Institute
Co-authored papers 8
Ruth Nussinov
Sackler School of Medicine, Tel Aviv University
Co-authored papers 6
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IBM T.J. Watson Research Center
Co-authored papers 5
Tak W Mak
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 4
Pablo G Camara
Perelman School of Medicine, University of Pennsylvania
Co-authored papers 3
Bert Vogelstein
Co-authored papers 3
Charles B Epstein
Co-authored papers 3
John Wagner
Co-authored papers 3
John J Rice
Co-authored papers 3
Britta Weigelt
Memorial Sloan Kettering Cancer Center
Co-authored papers 3
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Memorial Sloan Kettering Cancer Center
Co-authored papers 3
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Laboratorio Nazionale-Consorzio Interuniversitario per le Biotecnologie
Co-authored papers 3
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Co-authored papers 2
Chaitanya Bandlamudi
Co-authored papers 2
Anupama Reddy
Co-authored papers 2
Anne-Lise B??rresen-Dale
Institute for Cancer Research, Oslo University Hospital
Co-authored papers 2
Elisa de Stanchina
Co-authored papers 2
Frank Bartel
Co-authored papers 2
Jennifer R Wortman
Broad Institute of MIT and Harvard
Co-authored papers 2
Timothy R Rebbeck
Center for Cancer Equity and Engagement, Dana-Farber/Harvard Cancer Center
Co-authored papers 2
Timothy A Chan
Cleveland Clinic.
Co-authored papers 2
Shelley L Berger
Penn Epigenetics Institute, Perelman School of Medicine
Co-authored papers 2
Louise C Strong
University of Texas MD Anderson Cancer Center
Co-authored papers 2
Volker D??tsch
Institute for Biophysical Chemistry, Goethe-University
Co-authored papers 2
Mark Yandell
University of Utah
Co-authored papers 2
Release 1.2