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Author Details

Michelle Chan-Seng-Yue
Princess Margaret Cancer Centre
2012
33
23
PMIDPaper TitleJournal TitlePublished Year
37337105Transcriptomic classes of BCR-ABL1 lymphoblastic leukemia.Nat Genet2023
35019858Multiomic Profiling of Central Nervous System Leukemia Identifies mRNA Translation as a Therapeutic Target.Blood Cancer Discov2022
35618837A cellular hierarchy framework for understanding heterogeneity and predicting drug response in acute myeloid leukemia.Nat Med2022
36131042A primary hierarchically organized patient-derived model enables in depth interrogation of stemness driven by the coding and non-coding genome.Leukemia2022
33242413The Transition from Quiescent to Activated States in Human Hematopoietic Stem Cells Is Governed by Dynamic 3D Genome Reorganization.Cell Stem Cell2021
34244384Mapping the cellular origin and early evolution of leukemia in Down syndrome.Science2021
33958784A latent subset of human hematopoietic stem cells resists regenerative stress to preserve stemness.Nat Immunol2021
34343492TFEB-mediated endolysosomal activity controls human hematopoietic stem cell fate.Cell Stem Cell2021
33458693Sphingosine-1-phosphate receptor 3 potentiates inflammatory programs in normal and leukemia stem cells to promote differentiation.Blood Cancer Discov2021
31435024Cryptic genomic lesions in adverse-risk acute myeloid leukemia identified by integrated whole genome and transcriptome sequencing.Leukemia2020
32086311Relapse-Fated Latent Diagnosis Subclones in Acute B Lineage Leukemia Are Drug Tolerant and Possess Distinct Metabolic Programs.Cancer Discov2020
31932696Transcription phenotypes of pancreatic cancer are driven by genomic events during tumor evolution.Nat Genet2020
32051610Author Correction: Transcription phenotypes of pancreatic cancer are driven by genomic events during tumor evolution.Nat Genet2020
30686769Integration of Genomic and Transcriptional Features in Pancreatic Cancer Reveals Increased Cell Cycle Progression in Metastases.Cancer Cell2019
30665349BPG: Seamless, automated and interactive visualization of scientific data.BMC Bioinformatics2019
27750381Molecular heterogeneity of non-small cell lung carcinoma patient-derived xenografts closely reflect their primary tumors.Int J Cancer2017
27851734Erratum: A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns.Nature2017
27768182Association of Distinct Mutational Signatures With Correlates of Increased Immune Activity in Pancreatic Ductal Adenocarcinoma.JAMA Oncol2017
28068672Genomic hallmarks of localized, non-indolent prostate cancer.Nature2017
27800026Hypoxia increases genome-wide bivalent epigenetic marking by specific gain of H3K27me3.Epigenetics Chromatin2016
26546047Candidate DNA repair susceptibility genes identified by exome sequencing in high-risk pancreatic cancer.Cancer Lett2016
27822313Quantitative analysis of ChIP-seq data uncovers dynamic and sustained H3K4me3 and H3K27me3 modulation in cancer cells under hypoxia.Epigenetics Chromatin2016
27732578A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns.Nature2016
25609067Integrating RAS status into prognostic signatures for adenocarcinomas of the lung.Clin Cancer Res2015
28447939A Progesterone-CXCR4 Axis Controls Mammary Progenitor Cell Fate in the Adult Gland.Stem Cell Reports2015
26005866Spatial genomic heterogeneity within localized, multifocal prostate cancer.Nat Genet2015
24154973Identification of genes expressed by immune cells of the colon that are regulated by colorectal cancer-associated variants.Int J Cancer2014
25240283Hotspot activating PRKD1 somatic mutations in polymorphous low-grade adenocarcinomas of the salivary glands.Nat Genet2014
25173705SeqControl: process control for DNA sequencing.Nat Methods2014
24337703Identifying molecular features that distinguish fluvastatin-sensitive breast tumor cells.Breast Cancer Res Treat2014
23653877A case report and genetic characterization of a massive acinic cell carcinoma of the parotid with delayed distant metastases.Case Rep Oncol Med2013
24030976MYC phosphorylation at novel regulatory regions suppresses transforming activity.Cancer Res2013
23304554A Pilot Study Comparing HPV-Positive and HPV-Negative Head and Neck Squamous Cell Carcinomas by Whole Exome Sequencing.ISRN Oncol2012
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Collaborators

John E Dick
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 13
Paul C Boutros
University of California los angeles
Co-authored papers 13
John D McPherson
Ontario Institute for Cancer Research
Co-authored papers 12
Robert E Denroche
Ontario Institute for Cancer Research
Co-authored papers 9
Faiyaz Notta
2Ontario Institute for Cancer Research
Co-authored papers 9
Steven Gallinger
Lunenfeld Tanenbaum Research Institute, Mount Sinai Hospital, University of Toronto
Co-authored papers 8
Timothy Beck
Human Longevity Inc.
Co-authored papers 7
Ashton A Connor
Houston Methodist Hospital
Co-authored papers 7
Dianne Chadwick
University Health Network
Co-authored papers 6
Julie M Wilson
Ontario Institute for Cancer Research
Co-authored papers 6
Richard de Borja
The Hospital for Sick Children
Co-authored papers 6
Bradly G Wouters
Princess Margaret Cancer Centre, University Health Network and, University of Toronto
Co-authored papers 6
Lee Timms
Ontario Institute for Cancer Research, University Avenue
Co-authored papers 6
Nicholas J Harding
Big Data Institute, University of Oxford
Co-authored papers 6
John M S Bartlett
University of Edinburgh
Co-authored papers 6
Alex Murison
Princess Margaret Cancer Centre, University Health Network
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Gun Ho Jang
Ontario Institute for Cancer Research
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Maud H W Starmans
Ontario Institute for Cancer Research
Co-authored papers 6
Daryl Waggott
Ontario Institute for Cancer Research
Co-authored papers 5
Gloria M Petersen
Mayo Clinic
Co-authored papers 5
Lincoln Stein
Ontario Institute for Cancer Research, University Avenue
Co-authored papers 5
Nicholas Buchner
Ontario Institute for Cancer Research
Co-authored papers 5
Jeremy Johns
Rutgers Robert Wood Johnson Medical School
Co-authored papers 4
Ming-Sound Tsao
University Health Network, University of Toronto
Co-authored papers 4
Philippe Lambin
Maastricht University
Co-authored papers 4
Andrew M K Brown
Ontario Institute for Cancer Research
Co-authored papers 4
Kenneth C Chu
Ontario Institute for Cancer Research
Co-authored papers 4
Syed Haider
Institute of Cancer Research
Co-authored papers 4
Jianxin Wang
Ontario Institute for Cancer Research
Co-authored papers 4
Yu-Jia Shiah
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Co-authored papers 4
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