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Author Details

Elizabeth A Coker
Wellcome Sanger Institute
2014
14
10
PMIDPaper TitleJournal TitlePublished Year
35197630Effective drug combinations in breast, colon and pancreatic cancer cells.Nature2022
36241868AKT-mTORC1 reactivation is the dominant resistance driver for PI3Kβ/AKT inhibitors in PTEN-null breast cancer and can be overcome by combining with Mcl-1 inhibitors.Oncogene2022
33273059AZD0364 Is a Potent and Selective ERK1/2 Inhibitor That Enhances Antitumor Activity in <i>KRAS</i>-Mutant Tumor Models when Combined with the MEK Inhibitor, Selumetinib.Mol Cancer Ther2021
33339894SLFN11 informs on standard of care and novel treatments in a wide range of cancer models.Br J Cancer2021
33219674canSAR: update to the cancer translational research and drug discovery knowledgebase.Nucleic Acids Res2021
32988967AZD4320, A Dual Inhibitor of Bcl-2 and Bcl-x<sub>L</sub>, Induces Tumor Regression in Hematologic Cancer Models without Dose-limiting Thrombocytopenia.Clin Cancer Res2020
32627965Drug mechanism-of-action discovery through the integration of pharmacological and CRISPR screens.Mol Syst Biol2020
29452382Simulated ablation for detection of cells impacting paracrine signalling in histology analysis.Math Med Biol2019
31262731Differences in Signaling Patterns on PI3K Inhibition Reveal Context Specificity in <i>KRAS</i>-Mutant Cancers.Mol Cancer Ther2019
30496479canSAR: update to the cancer translational research and drug discovery knowledgebase.Nucleic Acids Res2019
30652614Leveraging Human Genetics to Guide Cancer Drug Development.JCO Clin Cancer Inform2018
28545060SiGNet: A signaling network data simulator to enable signaling network inference.PLoS One2017
26673713canSAR: an updated cancer research and drug discovery knowledgebase.Nucleic Acids Res2016
24304894canSAR: updated cancer research and drug discovery knowledgebase.Nucleic Acids Res2014
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Collaborators

Bissan Al-Lazikani
The University of Texas MD Anderson Cancer Center
Co-authored papers 7
Mathew J Garnett
Wellcome Sanger Institute
Co-authored papers 6
Patricia Jaaks
Wellcome Sanger Institute
Co-authored papers 6
Stephen Fawell
Oncology R&D
Co-authored papers 3
Paul Workman
The Institute of Cancer Research
Co-authored papers 3
Barry R Davies
Oncology R&D
Co-authored papers 2
Francis D Gibbons
Preclinical and Translational Sciences, Inc.
Co-authored papers 2
Gareth P Gregory
School of Clinical Sciences at Monash Health, Monash University
Co-authored papers 1
Andrea Bertotti
Candiolo Cancer Institute - FPO IRCCS
Co-authored papers 1
Michael Zinda
Repare Therapeutics Inc.
Co-authored papers 1
William McCoull
Oncology R&D
Co-authored papers 1
Andrew R Leach
European Bioinformatics Institute (EMBL-EBI)
Co-authored papers 1
Robert B Diebold
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Suzanne Carreira
The Institute of Cancer Research
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Cyril H Benes
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Kate F Byth
Oncology R&D
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Justin Cidado
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Terry MacIntyre
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Paula Lewis
Oncology R&D
Co-authored papers 1
Deborah Lawson
Oncology R&D
Co-authored papers 1
Nancy Su
Co-authored papers 1
Alwin G Schuller
Oncology R&D
Co-authored papers 1
Shannon K McWeeney
Oregon Health & Science University, University of California Berkeley
Co-authored papers 1
Johann S de Bono
The Institute for Cancer Research
Co-authored papers 1
Martin Wild
Oncology R&D
Co-authored papers 1
Livio Trusolino
Candiolo Cancer Institute - FPO IRCCS
Co-authored papers 1
Stephanos Ioannidis
H3 Biomedicine Inc.
Co-authored papers 1
Steven W Criscione
Oncology R&D
Co-authored papers 1
Joshua Armenia
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Co-authored papers 1
Kathleen Burke
Oncology R&D
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Release 1.2