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Author Details

Ian A Sigal
University of Pittsburgh
2004
114
39
PMIDPaper TitleJournal TitlePublished Year
36935071Who bears the load? IOP-induced collagen fiber recruitment over the corneoscleral shell.Exp Eye Res2023
378982292D or not 2D? Mapping the in-depth inclination of the collagen fibers of the corneoscleral shell.Exp Eye Res2023
37193214Instant polarized light microscopy pi (IPOLÏ¿) for quantitative imaging of collagen architecture and dynamics in ocular tissues.Opt Lasers Eng2023
36993476Predatory Bacteria can Reduce <i>Pseudomonas aeruginosa</i> Induced Corneal Perforation and Proliferation in a Rabbit Keratitis Model.bioRxiv2023
37215028Direct measurements of collagen fiber recruitment in the posterior pole of the eye.bioRxiv2023
37146902Predatory bacteria can reduce Pseudomonas aeruginosa induced corneal perforation and proliferation in a rabbit keratitis model.Ocul Surf2023
37207867A direct fiber approach to model sclera collagen architecture and biomechanics.Exp Eye Res2023
37365268Posterior scleral birefringence measured by triple-input polarization-sensitive imaging as a biomarker of myopia progression.Nat Biomed Eng2023
36965593Individual astrocyte morphology in the collagenous lamina cribrosa revealed by multicolor DiOlistic labeling.Exp Eye Res2023
36778384Instant polarized light microscopy pi (IPOLÏ¿) for quantitative imaging of collagen architecture and dynamics in ocular tissues.bioRxiv2023
36778255In vivo Modulation of Intraocular and Intracranial Pressures Causes Nonlinear and Non-monotonic Deformations of the Lamina Cribrosa and Scleral Canal.bioRxiv2023
35196556A high-accuracy and high-efficiency digital volume correlation method to characterize in-vivo optic nerve head biomechanics from optical coherence tomography.Acta Biomater2022
35568202Eye-specific 3D modeling of factors influencing oxygen concentration in the lamina cribrosa.Exp Eye Res2022
35862065Evidence of an Annexin A4 mediated plasma membrane repair response to biomechanical strain associated with glaucoma pathogenesis.J Cell Physiol2022
36454578Comparing Acute IOP-Induced Lamina Cribrosa Deformations Premortem and Postmortem.Transl Vis Sci Technol2022
34973204Lamina cribrosa vessel and collagen beam networks are distinct.Exp Eye Res2022
35266993A Workflow for Three-Dimensional Reconstruction and Quantification of the Monkey Optic Nerve Head Vascular Network.J Biomech Eng2022
35114213Real-time imaging of optic nerve head collagen microstructure and biomechanics using instant polarized light microscopy.Exp Eye Res2022
33103363Instant polarized light microscopy for imaging collagen microarchitecture and dynamics.J Biophotonics2021
34736887Interplay between intraocular and intracranial pressure effects on the optic nerve head in vivo.Exp Eye Res2021
31412277Scleral structure and biomechanics.Prog Retin Eye Res2020
33165501So-Called Lamina Cribrosa Defects May Mitigate IOP-Induced Neural Tissue Insult.Invest Ophthalmol Vis Sci2020
32805265Role of radially aligned scleral collagen fibers in optic nerve head biomechanics.Exp Eye Res2020
33001158Lamina Cribrosa Capillaries Straighten as Intraocular Pressure Increases.Invest Ophthalmol Vis Sci2020
32585309Collagen fiber interweaving is central to sclera stiffness.Acta Biomater2020
32211567Connective Tissue Remodeling in Myopia and its Potential Role in Increasing Risk of Glaucoma.Curr Opin Biomed Eng2020
29332130Cerebrospinal Fluid Pressure: Revisiting Factors Influencing Optic Nerve Head Biomechanics.Invest Ophthalmol Vis Sci2018
30025116Spatial Patterns and Age-Related Changes of the Collagen Crimp in the Human Cornea and Sclera.Invest Ophthalmol Vis Sci2018
30142444Peripapillary sclera architecture revisited: A tangential fiber model and its biomechanical implications.Acta Biomater2018
29847664Seeing the Hidden Lamina: Effects of Exsanguination on the Optic Nerve Head.Invest Ophthalmol Vis Sci2018
30372734Thin Lamina Cribrosa Beams Have Different Collagen Microstructure Than Thick Beams.Invest Ophthalmol Vis Sci2018
30304458Radial and Circumferential Collagen Fibers Are a Feature of the Peripapillary Sclera of Human, Monkey, Pig, Cow, Goat, and Sheep.Invest Ophthalmol Vis Sci2018
30277032Structured polarized light microscopy for collagen fiber structure and orientation quantification in thick ocular tissues.J Biomed Opt2018
29361354Gaze-Evoked Deformations in Optic Nerve Head Drusen: Repetitive Shearing as a Potential Factor in the Visual and Vascular Complications.Ophthalmology2018
29633576Polarized light microscopy for 3-dimensional mapping of collagen fiber architecture in ocular tissues.J Biophotonics2018
29574185Collagen fiber recruitment: A microstructural basis for the nonlinear response of the posterior pole of the eye to increases in intraocular pressure.Acta Biomater2018
29660327Crimp around the globe; patterns of collagen crimp across the corneoscleral shell.Exp Eye Res2018
29740064Tortuous Pore Path Through the Glaucomatous Lamina Cribrosa.Sci Rep2018
28687851Microstructural Crimp of the Lamina Cribrosa and Peripapillary Sclera Collagen Fibers.Invest Ophthalmol Vis Sci2017
28324116Thick Prelaminar Tissue Decreases Lamina Cribrosa Visibility.Invest Ophthalmol Vis Sci2017
28146238Collagen Architecture of the Posterior Pole: High-Resolution Wide Field of View Visualization and Analysis Using Polarized Light Microscopy.Invest Ophthalmol Vis Sci2017
29618852Mapping in-vivo optic nerve head strains caused by intraocular and intracranial pressures.Proc SPIE Int Soc Opt Eng2017
29338062An imaged-based inverse finite element method to determine <i>in-vivo</i> mechanical properties of the human trabecular meshwork.J Model Ophthalmol2017
28935889Formalin Fixation and Cryosectioning Cause Only Minimal Changes in Shape or Size of Ocular Tissues.Sci Rep2017
29049736Lamina Cribrosa Pore Shape and Size as Predictors of Neural Tissue Mechanical Insult.Invest Ophthalmol Vis Sci2017
29161320In-vivo effects of intraocular and intracranial pressures on the lamina cribrosa microstructure.PLoS One2017
29311754Correlation between Cerebral Hemodynamic and Perfusion Pressure Changes in Non-Human Primates.Proc SPIE Int Soc Opt Eng2017
28855629Location of the Central Retinal Vessel Trunk in the Laminar and Prelaminar Tissue of Healthy and Glaucomatous Eyes.Sci Rep2017
28528864Effects of collagen microstructure and material properties on the deformation of the neural tissues of the lamina cribrosa.Acta Biomater2017
28527594Whole-globe biomechanics using high-field MRI.Exp Eye Res2017
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Collaborators

NYU Grossman School of Medicine
Co-authored papers 40
NYU College of Arts and Sciences
Co-authored papers 35
Mie University School of Medicine, NYU School of Medicine, New York Medical College, New York University School of Medicine, Oregon Health & Science University, Tufts University School of Medicine, University of Pittsburgh School of Medicine, University of Pittsburgh School of Mediine
Co-authored papers 29
University of Pittsburgh
Co-authored papers 28
University of Pittsburgh
Co-authored papers 24
University of Pittsburgh School of Public Health
Co-authored papers 24
University of Pittsburgh, University of Mississippi
Co-authored papers 20
Institute of Biophysics, Chinese Academy of Sciences
Co-authored papers 19
University of Pittsburgh
Co-authored papers 16
Duquesne University
Co-authored papers 14
University of Pittsburgh
Co-authored papers 11
University of Alabama at Birmingham
Co-authored papers 10
Eye and Ear Institute, University of Pittsburgh School of Medicine
Co-authored papers 10
University of Pittsburgh School of Medicine
Co-authored papers 9
University of Pittsburgh School of Medicine
Co-authored papers 9
Massachusetts Institute of Technology
Co-authored papers 8
University of Pittsburgh
Co-authored papers 8
University of Pittsburgh
Co-authored papers 7
Institute of Physics, Nicolaus Copernicus University in Torun
Co-authored papers 6
NYU Grossman School of Medicine
Co-authored papers 6
Hawaii Macula and Retina Institute
Co-authored papers 6
University of California San Diego
Co-authored papers 6
NYU Grossman School of Medicine, New York University
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University of Pittsburgh
Co-authored papers 6
Singapore Eye Research Institute
Co-authored papers 5
University of Pittsburgh
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Neuroscience InstituteCarnegie Mellon University Pittsburgh PA 15213 USA.
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University of Pittsburgh
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