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Author Details

Patrizia Caposio
Vaccine and Gene Therapy Institute, Oregon Health & Science University
2001
54
25
PMIDPaper TitleJournal TitlePublished Year
36700640Virology under the Microscope-a Call for Rational Discourse.J Virol2023
37782657Proximity-dependent mapping of the HCMV US28 interactome identifies RhoGEF signaling as a requirement for efficient viral reactivation.PLoS Pathog2023
37772824HCMV UL8 interaction with β-catenin and DVL2 regulates viral reactivation in CD34<sup>+</sup> hematopoietic progenitor cells.J Virol2023
37565749Stabilization of the human cytomegalovirus UL136p33 reactivation determinant overcomes the requirement for UL135 for replication in hematopoietic cells.J Virol2023
36749635Late gene expression-deficient cytomegalovirus vectors elicit conventional T cells that do not protect against SIV.JCI Insight2023
36747736UL135 and UL136 Epistasis Controls Reactivation of Human Cytomegalovirus.bioRxiv2023
36700653Virology under the Microscope-a Call for Rational Discourse.mSphere2023
36700642Virology under the Microscope-a Call for Rational Discourse.mBio2023
35012351Advances in Model Systems for Human Cytomegalovirus Latency and Reactivation.mBio2022
33177198CD34<sup>+</sup> Hematopoietic Progenitor Cell Subsets Exhibit Differential Ability To Maintain Human Cytomegalovirus Latency and Persistence.J Virol2021
33555595Development of a huBLT Mouse Model to Study HCMV Latency, Reactivation, and Immune Response.Methods Mol Biol2021
34025614Human Cytomegalovirus Host Interactions: EGFR and Host Cell Signaling Is a Point of Convergence Between Viral Infection and Functional Changes in Infected Cells.Front Microbiol2021
33408225Human Cytomegalovirus UL7, miR-US5-1, and miR-UL112-3p Inactivation of FOXO3a Protects CD34<sup>+</sup> Hematopoietic Progenitor Cells from Apoptosis.mSphere2021
32268565Human Cytomegalovirus Infection Suppresses CD34<sup>+</sup> Progenitor Cell Engraftment in Humanized Mice.Microorganisms2020
31866424Human Cytomegalovirus miRNAs Regulate TGF-β to Mediate Myelosuppression while Maintaining Viral Latency in CD34<sup>+</sup> Hematopoietic Progenitor Cells.Cell Host Microbe2020
32850474The Differentiation of Human Cytomegalovirus Infected-Monocytes Is Required for Viral Replication.Front Cell Infect Microbiol2020
30729121Cancer Diagnostic and Predictive Biomarkers 2018.Biomed Res Int2019
31848362Characterization of a live-attenuated HCMV-based vaccine platform.Sci Rep2019
31548012Stabilization and formulation of a recombinant Human Cytomegalovirus vector for use as a candidate HIV-1 vaccine.Vaccine2019
31431555Human Cytomegalovirus US28 Ligand Binding Activity Is Required for Latency in CD34[+] Hematopoietic Progenitor Cells and Humanized NSG Mice.mBio2019
30894498OR14I1 is a receptor for the human cytomegalovirus pentameric complex and defines viral epithelial cell tropism.Proc Natl Acad Sci U S A2019
29691342Human Cytomegalovirus Encodes a Novel FLT3 Receptor Ligand Necessary for Hematopoietic Cell Differentiation and Viral Reactivation.mBio2018
28989973Cloning, Assembly, and Modification of the Primary Human Cytomegalovirus Isolate Toledo by Yeast-Based Transformation-Associated Recombination.mSphere2017
28428537Human Cytomegalovirus Induces Cellular and Humoral Virus-specific Immune Responses in Humanized BLT Mice.Sci Rep2017
26933055Complex Interplay of the UL136 Isoforms Balances Cytomegalovirus Replication and Latency.mBio2016
27432979Viral binding-induced signaling drives a unique and extended intracellular trafficking pattern during infection of primary monocytes.Proc Natl Acad Sci U S A2016
25820063A cytomegalovirus-based vaccine provides long-lasting protection against lethal Ebola virus challenge after a single dose.Vaccine2015
26118890Humanized mouse models of human cytomegalovirus infection.Curr Opin Virol2015
25352622Human cytomegalovirus-encoded pUL7 is a novel CEACAM1-like molecule responsible for promotion of angiogenesis.mBio2014
22414558A single-dose cytomegalovirus-based vaccine encoding tetanus toxin fragment C induces sustained levels of protective tetanus toxin antibodies in mice.Vaccine2012
22576344A cytomegalovirus-based vaccine expressing a single tumor-specific CD8+ T-cell epitope delays tumor growth in a murine model of prostate cancer.J Immunother2012
20869406The role of cytomegalovirus in angiogenesis.Virus Res2011
22241980A novel human cytomegalovirus locus modulates cell type-specific outcomes of infection.PLoS Pathog2011
21858240A replicating cytomegalovirus-based vaccine encoding a single Ebola virus nucleoprotein CTL epitope confers protection against Ebola virus.PLoS Negl Trop Dis2011
20930069IL-6 in human cytomegalovirus secretome promotes angiogenesis and survival of endothelial cells through the stimulation of survivin.Blood2011
20147408The Elk-1 and serum response factor binding sites in the major immediate-early promoter of human cytomegalovirus are required for efficient viral replication in quiescent cells and compensate for inactivation of the NF-kappaB sites in proliferating cells.J Virol2010
20480502The interferon-inducible gene IFI16 secretome of endothelial cells drives the early steps of the inflammatory response.Eur J Immunol2010
19301316Fine-tuning of catalytic properties of catechol 1,2-dioxygenase by active site tailoring.Chembiochem2009
18180342Phosphorothioate-modified oligodeoxynucleotides inhibit human cytomegalovirus replication by blocking virus entry.Antimicrob Agents Chemother2008
19120629New cell-based indicator assays for the detection of human cytomegalovirus infection and screening of inhibitors of viral immediate-early 2 protein activity.J Appl Microbiol2008
17070604Targeting the NF-kappaB pathway through pharmacological inhibition of IKK2 prevents human cytomegalovirus replication and virus-induced inflammatory response in infected endothelial cells.Antiviral Res2007
17576240Imbalance between activin A and follistatin drives postburn hypertrophic scar formation in human skin.Exp Dermatol2007
17699163A novel role of the interferon-inducible protein IFI16 as inducer of proinflammatory molecules in endothelial cells.J Biol Chem2007
17419715Activation of the virus-induced IKK/NF-kappaB signalling axis is critical for the replication of human cytomegalovirus in quiescent cells.Cell Microbiol2007
16504234The expression of p16INK4a tumor suppressor is upregulated by human cytomegalovirus infection and required for optimal viral replication.Virology2006
15016019Debridement and local application of tetracycline-loaded fibres in the management of persistent periodontitis: results after 12 months.J Clin Periodontol2004
15246266Evidence that the human cytomegalovirus 46-kDa UL72 protein is not an active dUTPase but a late protein dispensable for replication in fibroblasts.Virology2004
14990741Human cytomegalovirus stimulates cellular IKK2 activity and requires the enzyme for productive replication.J Virol2004
12752444The oxygenase component of phenol hydroxylase from Acinetobacter radioresistens S13.Eur J Biochem2003
12578320Molecular approaches to the identification and treatment monitoring of periodontal pathogens.New Microbiol2003
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Collaborators

Lindsey B Crawford
Vaccine and Gene Therapy Institute, Oregon Health & Science University
Co-authored papers 17
Jay A Nelson
Oregon Health and Science University
Co-authored papers 14
Daniel N Streblow
Vaccine and Gene Therapy Institute, Oregon Health and Science University
Co-authored papers 13
Andrew D Yurochko
Louisiana State University
Co-authored papers 13
Meaghan H Hancock
Vaccine and Gene Therapy Institute, Oregon Health & Science University
Co-authored papers 11
Felicia Goodrum
University of Arizona
Co-authored papers 10
Craig N Kreklywich
Vaccine and Gene Therapy Institute, Oregon Health and Science University
Co-authored papers 6
Andrew Pekosz
Co-authored papers 3
Benjamin R tenOever
NYU Grossman School of Medicine
Co-authored papers 3
Britt A Glaunsinger
UC Berkeley
Co-authored papers 3
Jennifer M Lund
Fred Hutchinson Cancer Research Center
Co-authored papers 3
Nicole L Diggins
Vaccine and Gene Therapy Institute, Oregon Health & Science University
Co-authored papers 3
Stephen P Goff
Columbia University
Co-authored papers 3
Balaji Manicassamy
University of Iowa
Co-authored papers 3
Ana Fernandez-Sesma
Icahn School of Medicine at Mount Sinai
Co-authored papers 3
Michael Emerman
Fred Hutchinson Cancer Center
Co-authored papers 3
Louis J Picker
Vaccine and Gene Therapy Institute, Oregon Health & Science University
Co-authored papers 3
Marco Vignuzzi
Quantitative Biosciences Institute (QBI) Coronavirus Research Group (QCRG)
Co-authored papers 3
Wesley I Sundquist
University of Utah School of Medicine
Co-authored papers 3
Nels C Elde
University of Utah School of Medicine
Co-authored papers 3
Rolf Renne
Co-authored papers 3
Adam S Lauring
University of Michigan ann arbor
Co-authored papers 3
Nicholas S Heaton
Duke University School of Medicine
Co-authored papers 3
Benhur Lee
Icahn School of Medicine at Mount Sinai
Co-authored papers 3
Adrianus C M Boon
Co-authored papers 3
Charles M Rice
Rockefeller University
Co-authored papers 3
Matthew D Weitzman
The Children's Hospital of Philadelphia
Co-authored papers 3
Mark T Heise
University of North Carolina at Chapel Hill.
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Arturo Casadevall
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Release 1.2