Author details

Full Name

Brian D Brown

Affiliation

ORCID

Career Start Year

2002

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
38057662	An IL-4 signalling axis in bone marrow drives pro-tumorigenic myelopoiesis.	Nature	2024
37487664	Pattern recognition receptor agonists in pathogen vaccines mediate antitumor T-cell cross-priming.	J Immunother Cancer	2023
36434108	Tumour antigen spreading mediated by vaccine-boosted CAR T cells.	Nature Reviews Immunology	2023
38091944	RNA vaccines: A transformational advance.	Immunity	2023
37081148	TREM2 macrophages drive NK cell paucity and dysfunction in lung cancer.	Nat Immunol	2023
37253090	Hepatic stellate cells maintain liver homeostasis through paracrine neurotrophin-3 signaling that induces hepatocyte proliferation.		2023
35347282	Neoadjuvant clinical trials provide a window of opportunity for cancer drug discovery.	Nat Med	2022
36103512	A shift in lung macrophage composition is associated with COVID-19 severity and recovery.	Sci Transl Med	2022
36095236	Targeting Macrophages with CAR T Cells Delays Solid Tumor Progression and Enhances Antitumor Immunity.	Cancer Immunol Res	2022
35999309	Cancer vaccines: the next immunotherapy frontier.	Nature Cancer	2022
35480113	<i>In Vivo</i> miRNA Decoy Screen Reveals miR-124a as a Suppressor of Melanoma Metastasis.	Front Oncol	2022
35784650	Development of an HIV reporter virus that identifies latently infected CD4<sup>+</sup> TÂ cells.	Cell Rep Methods	2022
36418317	Expanding cross-presenting dendritic cells enhances oncolytic virotherapy and is critical for long-term anti-tumor immunity.	Nat Commun	2022
35851878	Author Correction: Neoadjuvant clinical trials provide a window of opportunity for cancer drug discovery.	Nat Med	2022
35043110	Shift of lung macrophage composition is associated with COVID-19 disease severity and recovery.	bioRxiv	2022
35290801	Spatial CRISPR genomics identifies regulators of the tumor microenvironment.	Cell	2022
34135508	Tissue-resident macrophages provide a pro-tumorigenic niche to early NSCLC cells.	Nature	2021
33958797	BRAF<sup>V600E</sup>-induced senescence drives Langerhans cell histiocytosis pathophysiology.	Nat Med	2021
33568355	Exploiting Allosteric Properties of RAF and MEK Inhibitors to Target Therapy-Resistant Tumors Driven by Oncogenic BRAF Signaling.	Cancer Discov	2021
32499658	Author Correction: A conserved dendritic-cell regulatory program limits antitumour immunity.	Nature	2020
31988118	High-complexity extracellular barcoding using a viral hemagglutinin.	Proc Natl Acad Sci U S A	2020
32269339	A conserved dendritic-cell regulatory program limits antitumour immunity.	Nature	2020
32949492	"America First" Will Destroy U.S. Science.	Cell	2020
32505227	Immunology of COVID-19: Current State of the Science.	Immunity	2020
31375522	Antitumor T-cell Homeostatic Activation Is Uncoupled from Homeostatic Inhibition by Checkpoint Blockade.	Cancer Discov	2019
31557273	Long-term surviving influenza infected cells evade CD8+ T cell mediated clearance.	PLoS Pathog	2019
30629937	A miRNA-Mediated Approach to Dissect the Complexity of Tumor-Initiating Cell Function and Identify miRNA-Targeting Drugs.	Stem Cell Reports	2019
31186238	Î²-Catenin Activation Promotes Immune Escape and Resistance to Anti-PD-1 Therapy in Hepatocellular Carcinoma.	Cancer Discov	2019
30686579	The cis-Regulatory Atlas of the Mouse Immune System.	Cell	2019
30962585	Systemic clinical tumor regressions and potentiation of PD1 blockade with in situ vaccination.	Nat Med	2019
29466757	Quiescent Tissue Stem Cells Evade Immune Surveillance.	Immunity	2018
30355233	miR-146a Suppresses SUMO1 Expression and Induces Cardiac Dysfunction in Maladaptive Hypertrophy.	Circulation Research	2018
30343902	Protein Barcodes Enable High-Dimensional Single-Cell CRISPR Screens.	Cell	2018
30143629	SIRT6 haploinsufficiency induces BRAF<sup>V600E</sup> melanoma cell resistance to MAPK inhibitors via IGF signalling.	Nat Commun	2018
29273502	miR-25 Tough Decoy Enhances Cardiac Function in Heart Failure.	Molecular Therapy	2018
28263958	Genomic instability during reprogramming by nuclear transfer is DNA replication dependent.	Nature Cell Biology	2017
28625571	Micromanaging Tolerance in Hemophilia A Gene Therapy.	Molecular Therapy	2017
26619012	Mapping the effects of drugs on the immune system.	Nat Biotechnol	2016
27346354	Cbx8 Acts Non-canonically with Wdr5 to Promote Mammary Tumorigenesis.	Cell Rep	2016
27096321	Expansion and Activation of CD103(+) Dendritic Cell Progenitors at the Tumor Site Enhances Tumor Responses to Therapeutic PD-L1 and BRAF Inhibition.	Immunity	2016
26982360	Silence of the ROS.	Immunity	2016
26672545	Authorship: Archives and citation miss equal authors.	Nature	2015
25677173	Identification of metastasis-suppressive microRNAs in primary melanoma.	Journal of the National Cancer Institute	2015
25941795	Lymphoma: immune evasion strategies.	Cancers (Basel)	2015
25849425	A shot in the bone corrects a genetic disease.	Molecular Therapy	2015
26524661	GFP-specific CD8 T cells enable targeted cell depletion and visualization of T-cell interactions.	Nat Biotechnol	2015
26456833	Myeloid Dysregulation in a Human Induced Pluripotent Stem Cell Model of PTPN11-Associated Juvenile Myelomonocytic Leukemia.	Cell Rep	2015
25083866	TLR signals induce phagosomal MHC-I delivery from the endosomal recycling compartment to allow cross-presentation.	Cell	2014
25403145	Hepatitis C virus genetics affects miR-122 requirements and response to miR-122 inhibitors.	Nat Commun	2014
24270517	The miR-126-VEGFR2 axis controls the innate response to pathogen-associated nucleic acids.	Nat Immunol	2014