Author details

Full Name

Christopher J Ricketts

Affiliation

ORCID

Career Start Year

2003

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36987696	TFEB and TFE3 drive kidney cystogenesis andÂ tumorigenesis.	EMBO Mol Med	2023
37561409	Cryptic splice mutation in the fumarate hydratase gene in patients with clinical manifestations of Hereditary Leiomyomatosis and Renal Cell Cancer.	Hum Mol Genet	2023
37095531	High-throughput and targeted drug screens identify pharmacological candidates against MiT-translocation renal cell carcinoma.	J Exp Clin Cancer Res	2023
37331486	PRDM10 RCC: A Birt-Hogg-DubÃ©-like Syndrome Associated With Lipoma and Highly Penetrant, Aggressive Renal Tumors Morphologically Resembling Type 2 Papillary Renal Cell Carcinoma.	Urology	2023
37182269	Comparative analyses define differences between BHD-associated renal tumour and sporadic chromophobe renal cell carcinoma.	EBioMedicine	2023
37353242	EDITORIAL COMMENT.		2023
33067352	A germline 1;3 translocation disrupting the gene: a novel genetic cause for von Hippel-Lindau.	Journal of Medical Genetics	2022
35396773	Targeting chemoresistance in Xp11.2 translocation renal cell carcinoma using a novel polyamide-chlorambucil conjugate.	Cancer Science	2022
35754026	Inhibition of HSP 90 is associated with potent anti-tumor activity in Papillary Renal Cell Carcinoma.	J Exp Clin Cancer Res	2022
35469800	Differential VHL Mutation Patterns in Bilateral Clear Cell RCC Distinguishes Between Independent Primary Tumors and Contralateral Metastatic Disease.	Urology	2022
36455002	Kidney tumors associated with germline mutations of FH and SDHB show a CpG island methylator phenotype (CIMP).	PLoS One	2022
34405000	MicroRNA Profiling of Morphologically Heterogeneous Clear Cell Renal Cell Carcinoma.	J Cancer	2021
33527590	Characterization of genetically defined sporadic and hereditary type 1 papillary renal cell carcinoma cell lines.	Genes Chromosomes Cancer	2021
33675279	Comprehensive characterization of Alu-mediated breakpoints in germline VHL gene deletions and rearrangements in patients from 71 VHL families.	Human Mutation	2021
33358149	Summary from the Kidney Cancer Association's Inaugural Think Thank: Coalition for a Cure.	Clin Genitourin Cancer	2021
33242557	Clinical and Molecular Characterization of Microphthalmia-associated Transcription Factor (MITF)-related Renal Cell Carcinoma.	Urology	2021
32785680	Glycolytic metabolism of pathogenic T cells enables early detection of GVHD by 13C-MRI.	Blood	2021
33165095	Multifocal Renal Cell Carcinomas With Somatic IDH2 Mutation: Report of a Previously Undescribed Neoplasm.	Am J Surg Pathol	2021
33402335	Mitochondrial DNA alterations underlie an irreversible shift to aerobic glycolysis in fumarate hydratase-deficient renal cancer.	Sci Signal	2021
31923397	Integrated Proteogenomic Characterization of Clear Cell Renal Cell Carcinoma.	Cell	2020
32083993	Growth Rates of Genetically Defined Renal Tumors: Implications for Active Surveillance and Intervention.	J Clin Oncol	2020
32259323	Novel renal medullary carcinoma cell lines, UOK353 and UOK360, provide preclinical tools to identify new therapeutic treatments.	Genes Chromosomes Cancer	2020
32413160	Complexities in estimating the true risk of hereditary leiomyomatosis and renal cell carcinoma and the development of kidney cancer.	Cancer	2020
31278395	The Cancer Genome Atlas of renal cell carcinoma: findings and clinical implications.	Nature Reviews Urology	2019
31804603	Proteasome inhibition disrupts the metabolism of fumarate hydratase- deficient tumors by downregulating p62 and c-Myc.	Sci Rep	2019
31675502	Integrated Proteogenomic Characterization of Clear Cell Renal Cell Carcinoma.	Cell	2019
30452964	CDC73 Germline Mutation in a Family With Mixed Epithelial and Stromal Tumors.	Urology	2019
30548481	Germline mutations of renal cancer predisposition genes and clinical relevance in Chinese patients with sporadic, early-onset disease.	Cancer	2019
31088840	The Metabolic Basis of Kidney Cancer.	Cancer Discovery	2019
29677504	Multi-regional Sequencing Elucidates the Evolution of Clear Cell Renal Cell Carcinoma.	Cell	2018
29925010	The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma.	Cell Rep	2018
29875480	The origin, evolution and route to metastasis of clear cell RCC.	Nature Reviews Nephrology	2018
30372397	Chromosome 3p Loss-Orchestrated VHL, HIF, and Epigenetic Deregulation in Clear Cell Renal Cell Carcinoma.	J Clin Oncol	2018
29535838	Targeting loss of the Hippo signaling pathway in <i>NF2</i>-deficient papillary kidney cancers.	Oncotarget	2018
29617669	The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma.	Cell Rep	2018
28031562	Kidney cancer in 2016: RCC - advances in targeted therapeutics and genomics.	Nature Reviews Urology	2017
28736828	Genomic and metabolic characterization of a chromophobe renal cell carcinoma cell line model (UOK276).	Genes Chromosomes Cancer	2017
29097620	Insights into Epigenetic Remodeling in VHL-Deficient Clear Cell Renal Cell Carcinoma.	Cancer Discovery	2017
28196407	Comprehensive genomic and phenotypic characterization of germline FH deletion in hereditary leiomyomatosis and renal cell carcinoma.	Genes Chromosomes Cancer	2017
27682873	Haploinsufficiency in tumor predisposition syndromes: altered genomic transcription in morphologically normal cells heterozygous for VHL or TSC mutation.	Oncotarget	2017
25024072	Vascular Endothelial Growth Factor Receptor-Targeted Therapy in Succinate Dehydrogenase C Kidney Cancer.	J Clin Oncol	2016
27192682	Papillary Renal-Cell Carcinoma.	N Engl J Med	2016
27174753	Patient-specific factors influence somatic variation patterns in von Hippel-Lindau disease renal tumours.	Nat Commun	2016
26719882	SDHB-Deficient Cancers: The Role of Mutations That Impair Iron Sulfur Cluster Delivery.	J Natl Cancer Inst	2016
27070709	SnapShot: Renal Cell Carcinoma.	Cancer Cell	2016
26536169	Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma.	N Engl J Med	2016
27728802	Targeting HIF2Î± in Clear-Cell Renal Cell Carcinoma.	Cancer Cell	2016
26484545	Gender Specific Mutation Incidence and Survival Associations in Clear Cell Renal Cell Carcinoma (CCRCC).	PLoS ONE	2015
25564569	New strategies in renal cell carcinoma: targeting the genetic and metabolic basis of disease.	Clinical Cancer Research	2015
24642075	The genetic basis of pheochromocytoma and paraganglioma: implications for management.	Urology	2014