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Author Details

Philip Lijnzaad
Princess Maxima Center for Pediatric Oncology
1990
40
22
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36111639Lysosomal glycogen accumulation in Pompe disease results in disturbed cytoplasmic glycogen metabolism.J Inherit Metab Dis2023
35085008Improved Gene Fusion Detection in Childhood Cancer Diagnostics Using RNA Sequencing.JCO Precis Oncol2022
33848015LGR6 marks nephron progenitor cells.Dev Dyn2021
33547074Tumor to normal single-cell mRNA comparisons reveal a pan-neuroblastoma cancer cell.Sci Adv2021
32161258An organoid biobank for childhood kidney cancers that captures disease and tissue heterogeneity.Nat Commun2020
33280256Genome-wide off-rates reveal how DNA binding dynamics shape transcription factor function.Mol Syst Biol2020
31083661The ability of transcription factors to differentially regulate gene expression is a crucial component of the mechanism underlying inversion, a frequently observed genetic interaction pattern.PLoS Comput Biol2019
31226206CHETAH: a selective, hierarchical cell type identification method for single-cell RNA sequencing.Nucleic Acids Res2019
27979920Molecular mechanisms that distinguish TFIID housekeeping from regulatable SAGA promoters.EMBO J2017
28781745Developing a strategy for computational lab skills training through Software and Data Carpentry: Experiences from the ELIXIR Pilot action.F1000Res2017
25990325FOXO target gene CTDSP2 regulates cell cycle progression through Ras and p21(Cip1/Waf1).Biochem J2015
26700642A high-resolution gene expression atlas of epistasis between gene-specific transcription factors exposes potential mechanisms for genetic interactions.BMC Biol2015
24334265A novel microscopy-based high-throughput screening method to identify proteins that regulate global histone modification levels.J Biomol Screen2014
24766815Large-scale genetic perturbations reveal regulatory networks and an abundance of gene-specific repressors.Cell2014
24952590Cell cycle population effects in perturbation studies.Mol Syst Biol2014
23503660A central role for TFIID in the pluripotent transcription circuitry.Nature2013
23785440Centromere binding and a conserved role in chromosome stability for SUMO-dependent ubiquitin ligases.PLoS One2013
21459853Gcn4 misregulation reveals a direct role for the evolutionary conserved EKC/KEOPS in the t6A modification of tRNAs.Nucleic Acids Res2011
21596317The specificity and topology of chromatin interaction pathways in yeast.Mol Cell2011
20620961A consensus of core protein complex compositions for Saccharomyces cerevisiae.Mol Cell2010
21145464Functional overlap and regulatory links shape genetic interactions between signaling pathways.Cell2010
19401678Adaptable gene-specific dye bias correction for two-channel DNA microarrays.Mol Syst Biol2009
18186474On defining the dynamics of hydrophobic patches on protein surfaces.Proteins2008
16630888Genome-wide location of the coactivator mediator: Binding without activation and transient Cdk8 interaction on DNA.Mol Cell2006
15640797An expression profile for diagnosis of lymph node metastases from primary head and neck squamous cell carcinomas.Nat Genet2005
15837421Genome-wide analyses reveal RNA polymerase II located upstream of genes poised for rapid response upon S. cerevisiae stationary phase exit.Mol Cell2005
11752248The Ensembl genome database project.Nucleic Acids Res2002
11125078RHdb: the Radiation Hybrid database.Nucleic Acids Res2001
10592206RHdb: the radiation hybrid database.Nucleic Acids Res2000
11178259Accessing and distributing EMBL data using CORBA (common object request broker architecture).Genome Biol2000
9847154The radiation hybrid database.Nucleic Acids Res1999
10089201A proposal for a standard CORBA interface for genome maps.Bioinformatics1999
9784132A physical map of 30,000 human genes.Science1998
9399810The Radiation Hybrid Database.Nucleic Acids Res1998
9016508The Radiation Hybrid Database.Nucleic Acids Res1997
9223180Hydrophobic patches on protein subunit interfaces: characteristics and prediction.Proteins1997
9322045A CORBA server for the Radiation Hybrid DataBase.Proc Int Conf Intell Syst Mol Biol1997
8844873Hydrophobic patches on the surfaces of protein structures.Proteins1996
8916227A method for detecting hydrophobic patches on protein surfaces.Proteins1996
2253614Tertiary structure of two-electron reduced Megasphaera elsdenii flavodoxin and some implications, as determined by two-dimensional 1H-NMR and restrained molecular dynamics.Eur J Biochem1990
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Collaborators

Frank C P Holstege
Princess Maxima Center for Pediatric Oncology
Co-authored papers 23
Patrick Kemmeren
Princess Maxima Center for Pediatric Oncology
Co-authored papers 14
Dik van Leenen
Center for Molecular Medicine, University Medical Center Utrecht, Utrecht University
Co-authored papers 11
Thanasis Margaritis
Princess Maxima Center for Pediatric Oncology
Co-authored papers 9
Marian J A Groot Koerkamp
Princess Maxima Center for Pediatric Oncology Research
Co-authored papers 8
Mariel O Brok
Princess Maxima Center for Pediatric Oncology
Co-authored papers 6
Tineke L Lenstra
the Netherlands Cancer Institute, Oncode Institute
Co-authored papers 6
Joris J Benschop
Center for Molecular Medicine, University Medical Center Utrecht
Co-authored papers 6
Sander R van Hooff
Princess Maxima Center for Pediatric Oncology
Co-authored papers 6
Nathalie Brabers
University Medical Centre Utrecht, Universiteitsweg
Co-authored papers 6
Loes A L van de Pasch
University Medical Centre Utrecht, Universiteitsweg
Co-authored papers 5
Katrin Sameith
Center for Molecular and Cellular Bioengineering
Co-authored papers 5
Eva Apweiler
University Medical Centre Utrecht, Universiteitsweg
Co-authored papers 4
Antony J Miles
University Medical Centre Utrecht, Universiteitsweg
Co-authored papers 4
Cheuk W Ko
University Medical Centre Utrecht, Universiteitsweg
Co-authored papers 3
Sake van Wageningen
Oncode Institute, The Netherlands Cancer Institute
Co-authored papers 3
Berend Snel
Utrecht University
Co-authored papers 3
Linda V Bakker
Wageningen University and Research
Co-authored papers 3
Jan J Molenaar
Co-authored papers 2
Jaap Heringa
VU University Amsterdam
Co-authored papers 2
Richard Durbin
University of Cambridge
Co-authored papers 1
Jean Weissenbach
Institut Francois Jacob, CNRS, Universite Paris-Saclay
Co-authored papers 1
Marcel Kool
Hopp Children's Cancer Center (KiTZ)
Co-authored papers 1
Eduardo Eyras
Co-authored papers 1
Matthew Pocock
Newcastle University
Co-authored papers 1
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University of California San Francisco
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Release 1.2