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Author Details

Mikhail A Gavrilin
The Ohio State University, Wexner Medical Center
1988
70
32
PMIDPaper TitleJournal TitlePublished Year
37548464Blood collection in heparin vs. EDTA results in an inflammasome-independent increase in monocyte distribution width at 4⿯h.Clin Chem Lab Med2023
34694354Pathways of Microcirculatory Endothelial Dysfunction in Obstructive Sleep Apnea: A Comprehensive Ex Vivo Evaluation in Human Tissue.Am J Hypertens2022
35568196The central inflammasome adaptor protein ASC activates the inflammasome after transition from a soluble to an insoluble state.J Biol Chem2022
35252032CFTR Modulators Restore Acidification of Autophago-Lysosomes and Bacterial Clearance in Cystic Fibrosis Macrophages.Front Cell Infect Microbiol2022
35128458Inflammasome Activation in an In Vitro Sepsis Model Recapitulates Increased Monocyte Distribution Width Seen in Patients With Sepsis.Crit Care Explor2022
33441602Gasdermin D restricts Burkholderia cenocepacia infection in vitro and in vivo.Sci Rep2021
33568399cAbl Kinase Regulates Inflammasome Activation and Pyroptosis via ASC Phosphorylation.J Immunol2021
34426734Elevated Expression of MiR-17 in Microglia of Alzheimer's Disease Patients Abrogates Autophagy-Mediated Amyloid-β Degradation.Front Immunol2021
34103646Author Correction: Gasdermin D restricts Burkholderia cenocepacia infection in vitro and in vivo.Sci Rep2021
34367171Human Placental Trophoblasts Infected by <i>Listeria monocytogenes</i> Undergo a Pro-Inflammatory Switch Associated With Poor Pregnancy Outcomes.Front Immunol2021
33208300Defective immunometabolism pathways in cystic fibrosis macrophages.J Cyst Fibros2021
32265920Inflammasome Adaptor ASC Is Highly Elevated in Lung Over Plasma and Relates to Inflammation and Lung Diffusion in the Absence of Speck Formation.Front Immunol2020
33123123Omega-3 Docosahexaenoic Acid (DHA) Impedes Silica-Induced Macrophage Corpse Accumulation by Attenuating Cell Death and Potentiating Efferocytosis.Front Immunol2020
32852363Brief Report: Increased Cotinine Concentrations are Associated With Reduced Expression of Cathelicidin (LL-37) and NOD-2 in Alveolar Macrophages of PLWH Who Smoke.J Acquir Immune Defic Syndr2020
30737168Methylomic correlates of autophagy activity in cystic fibrosis.J Cyst Fibros2019
31637841Caspase-11 counteracts mitochondrial ROS-mediated clearance of Staphylococcus aureus in macrophages.EMBO Rep2019
31803174Caspase-11 Mediates Neutrophil Chemotaxis and Extracellular Trap Formation During Acute Gouty Arthritis Through Alteration of Cofilin Phosphorylation.Front Immunol2019
31849970Adenovirus VA RNAI Blocks ASC Oligomerization and Inhibits NLRP3 Inflammasome Activation.Front Immunol2019
31616405Docosahexaenoic Acid Suppresses Silica-Induced Inflammasome Activation and IL-1 Cytokine Release by Interfering With Priming Signal.Front Immunol2019
29162504Checks and Balances between Autophagy and Inflammasomes during Infection.J Mol Biol2018
30165781CASP4/caspase-11 promotes autophagosome formation in response to bacterial infection.Autophagy2018
30061379Relative Roles of Listeriolysin O, InlA, and InlB in Listeria monocytogenes Uptake by Host Cells.Infect Immun2018
29632532Complement Receptor 3-Mediated Inhibition of Inflammasome Priming by Ras GTPase-Activating Protein During <i>Francisella tularensis</i> Phagocytosis by Human Mononuclear Phagocytes.Front Immunol2018
29365280Microparticulate Caspase 1 Regulates Gasdermin D and Pulmonary Vascular Endothelial Cell Injury.Am J Respir Cell Mol Biol2018
29036393Angiotensin Receptor Expression and Vascular Endothelial Dysfunction in Obstructive Sleep Apnea.Am J Hypertens2018
27421477Ethanol and Other Short-Chain Alcohols Inhibit NLRP3 Inflammasome Activation through Protein Tyrosine Phosphatase Stimulation.J Immunol2016
27911947The Yersinia pestis Effector YopM Inhibits Pyrin Inflammasome Activation.PLoS Pathog2016
25312739Macrophages in immunopathology of atherosclerosis: a target for diagnostics and therapy.Curr Pharm Des2015
26253471Detection of nitric oxide production in cell cultures by luciferin-luciferase chemiluminescence.Biochem Biophys Res Commun2015
26599267Monocyte Caspase-1 Is Released in a Stable, Active High Molecular Weight Complex Distinct from the Unstable Cell Lysate-Activated Caspase-1.PLoS One2015
26686473Caspase-11 and caspase-1 differentially modulate actin polymerization via RhoA and Slingshot proteins to promote bacterial clearance.Sci Rep2015
25993107Inflammasome priming is similar for francisella species that differentially induce inflammasome activation.PLoS One2015
25629767House Dust Mite Allergens and the Induction of Monocyte Interleukin 1β Production That Triggers an IκBζ-Dependent Granulocyte Macrophage Colony-Stimulating Factor Release from Human Lung Epithelial Cells.Am J Respir Cell Mol Biol2015
25819532Supernatants from stored red blood cell (RBC) units, but not RBC-derived microvesicles, suppress monocyte function in vitro.Transfusion2015
24658576Receptor interacting protein-2 plays a critical role in human lung epithelial cells survival in response to Fas-induced cell-death.PLoS One2014
24783062Virulent Type A Francisella tularensis actively suppresses cytokine responses in human monocytes.Front Cell Infect Microbiol2014
24623131Inflammasome priming by lipopolysaccharide is dependent upon ERK signaling and proteasome function.J Immunol2014
23269671Analysis of human bronchial epithelial cell proinflammatory response to Burkholderia cenocepacia infection: inability to secrete il-1β.J Biol Chem2013
22368275Activation of the pyrin inflammasome by intracellular Burkholderia cenocepacia.J Immunol2012
22842458Tyrosine phosphatase inhibition induces an ASC-dependent pyroptosis.Biochem Biophys Res Commun2012
22658523Caspase-11 promotes the fusion of phagosomes harboring pathogenic bacteria with lysosomes by modulating actin polymerization.Immunity2012
21097506Apoptosis-associated speck-like protein (ASC) controls Legionella pneumophila infection in human monocytes.J Biol Chem2011
21997369Autophagy stimulation by rapamycin suppresses lung inflammation and infection by Burkholderia cenocepacia in a model of cystic fibrosis.Autophagy2011
21687407Francisella Recognition by Inflammasomes: Differences between Mice and Men.Front Microbiol2011
21713115Asc-dependent and independent mechanisms contribute to restriction of legionella pneumophila infection in murine macrophages.Front Microbiol2011
20360862Mycoplasma suppression of THP-1 Cell TLR responses is corrected with antibiotics.PLoS One2010
20620944Interleukin-1beta selectively expands and sustains interleukin-22+ immature human natural killer cells in secondary lymphoid tissue.Immunity2010
19218196Gene expression profiling identifies MMP-12 and ADAMDEC1 as potential pathogenic mediators of pulmonary sarcoidosis.Am J Respir Crit Care Med2009
19343209Caspase-7 activation by the Nlrc4/Ipaf inflammasome restricts Legionella pneumophila infection.PLoS Pathog2009
19494323Pyrin critical to macrophage IL-1beta response to Francisella challenge.J Immunol2009
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Collaborators

Mark D Wewers
The Ohio State University College of Medicine
Co-authored papers 38
Anasuya Sarkar
The Ohio State University, OH and The Davis Heart and Lung Research Institute
Co-authored papers 7
Larry S Schlesinger
Texas Biomedical Research Institute
Co-authored papers 6
Clay B Marsh
West Virginia University School of Medicine
Co-authored papers 6
Mark W Hall
Nationwide Children's Hospital, The Ohio State University
Co-authored papers 5
Nina L Knatz
Co-authored papers 3
Jyotsna Nateri
Center for Clinical and Translational Research, Nationwide Children's Hospital
Co-authored papers 2
Matthew C Exline
Ohio State University Wexner Medical Center
Co-authored papers 2
Valerie P Wright
Ohio State University Wexner Medical Center
Co-authored papers 1
Kathleen K Nicol
Nationwide Children's Hospital
Co-authored papers 1
Jiahuai Han
Co-authored papers 1
Jennifer A Muszynski
0Nationwide Children's Hospital
Co-authored papers 1
Sandya Liyanarachchi
The Ohio State University Comprehensive Cancer Center, Comprehensive Cancer Center
Co-authored papers 1
Justin Bale
The Research Institute.
Co-authored papers 1
Nizar N Jarjour
Co-authored papers 1
Yijie Wang
Center for Perinatal Research, Nationwide Children's Hospital
Co-authored papers 1
David Frankhouser
Co-authored papers 1
Soledad Fernandez
McGill University
Co-authored papers 1
Eusondia Arnett
Texas Biomedical Research Institute
Co-authored papers 1
Release 1.2