Author details

Full Name

Lars Zender

Affiliation

ORCID

Career Start Year

1999

Papers

176

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36915613	Clinical outcome of biomarker-guided therapies in adult patients with tumors of the nervous system.	Neurooncol Adv	2023
36449018	A Pro-Regenerative Environment Triggers Premalignant to Malignant Transformation of Senescent Hepatocytes.	Cancer Research	2023
37854502	Myasthenia gravis as initial presentation of a pancreatic neuroendocrine tumor: A case report.		2023
37686593	Diagnostic Approaches for Neuroendocrine Neoplasms of Unknown Primary (NEN-UPs) and Their Prognostic Relevance-A Retrospective, Long-Term Single-Center Experience.		2023
37215571	imaging of CD8 T cells in metastatic cancer patients: first clinical experience with simultaneous [Zr]Zr-Df-IAB22M2C PET/MRI.		2023
36906109	MYC determines lineage commitment in KRAS-driven primary liver cancer development.	J Hepatol	2023
37258875	Advances in PET imaging of cancer.		2023
36749424	NOTCH3 missense mutations as predictor of long-term response to gemcitabine in a patient with epithelioid hemangioendothelioma.	J Cancer Res Clin Oncol	2023
37373636	Diagnostic Performance of Dynamic Whole-Body Patlak [F]FDG-PET/CT in Patients with Indeterminate Lung Lesions and Lymph Nodes.		2023
37359009	Long-term prognostic factors for PRRT in neuroendocrine tumors.		2023
37226670	Design and Optimization of Novel Benzimidazole- and Imidazo[4,5-]pyridine-Based ATM Kinase Inhibitors with Subnanomolar Activities.		2023
35286086	Gefitinib-Tamoxifen Hybrid Ligands as Potent Agents against Triple-Negative Breast Cancer.	Journal of Medicinal Chemistry	2022
36233666	Inflammatory Surrogate Parameters for Predicting Ifosfamide-Induced Neurotoxicity in Sarcoma Patients.	Journal of Clinical Medicine	2022
35957893	NUT Carcinoma-An Underdiagnosed Malignancy.	Frontiers in Oncology	2022
35875148	Controversial Role of the Immune Checkpoint OX40L Expression on Platelets in Breast Cancer Progression.	Frontiers in Oncology	2022
35868124	Scaffold modified Vemurafenib analogues as highly selective mitogen activated protein kinase kinase 4 (MKK4) inhibitors.	European Journal of Medicinal Chemistry	2022
36387105	Case report: Immunovirotherapy as a novel add-on treatment in a patient with thoracic NUT carcinoma.	Front Oncol	2022
34980913	CLUSTER guide RNAs enable precise and efficient RNA editing with endogenous ADAR enzymes in vivo.	Nature Biotechnology	2022
35181768	Author Correction: Platelet GPIbÎ± is a mediator and potential interventional target for NASH and subsequent liver cancer.	Nat Med	2022
35167750	Development of the First Covalent Monopolar Spindle Kinase 1 (MPS1/TTK) Inhibitor.	J Med Chem	2022
35325634	Development of novel urea-based ATM kinase inhibitors with subnanomolar cellular potency and high kinome selectivity.	Eur J Med Chem	2022
35122079	LXRÎ± activation and Raf inhibition trigger lethal lipotoxicity in liver cancer.	Nature Cancer	2021
34129825	Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations.	Cancer Cell	2021
33538861	Platelet-expressed immune checkpoint regulator GITRL in breast cancer.	Cancer Immunology, Immunotherapy	2021
34064565	Platelet-Expressed Synaptophysin (pSyn) as Novel Biomarker in Neuroendocrine Malignancies.	Cancers	2021
33794385	Design and synthesis of 1H-pyrazolo[3,4-b]pyridines targeting mitogen-activated protein kinase kinase 4 (MKK4) - A promising target for liver regeneration.	European Journal of Medicinal Chemistry	2021
33458956	Long-term remission of small cell lung cancer after reactivation of tuberculosis following immune-checkpoint blockade: A case report.	Thoracic Cancer	2021
34145038	MYC- and MIZ1-Dependent Vesicular Transport of Double-Strand RNA Controls Immune Evasion in Pancreatic Ductal Adenocarcinoma.	Cancer Research	2021
33930309	Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations.	Cancer Cell	2021
33762733	NASH limits anti-tumour surveillance in immunotherapy-treated HCC.	Nature	2021
34326518	The immunological and metabolic landscape in primary and metastatic liver cancer.	Nature Reviews Cancer	2021
34302061	Exploiting lipotoxicity for the treatment of liver cancer.	British Journal of Cancer	2021
33816291	Platelet-Expressed TNFRSF13B (TACI) Predicts Breast Cancer Progression.	Frontiers in Oncology	2021
33372710	An IgG-based bispecific antibody for improved dual targeting in PSMA-positive cancer.	EMBO Mol Med	2021
33199152	From off-to on-target: New BRAF-inhibitor-template-derived compounds selectively targeting mitogen activated protein kinase kinase 4 (MKK4).	European Journal of Medicinal Chemistry	2021
33140149	Impact of the COVID-19 pandemic on an interdisciplinary endoscopy unit in a German "hotspot" area: a single center experience.	Surgical Endoscopy and Other Interventional Techniques	2021
34853305	Platelet PD-L1 reflects collective intratumoral PD-L1 expression and predicts immunotherapy response in non-small cell lung cancer.	Nature Communications	2021
33076423	Ramucirumab in Combination with Pembrolizumab in Treatment-NaÃ¯ve Advanced Gastric or GEJ Adenocarcinoma: Safety and Antitumor Activity from the Phase 1a/b JVDF Trial.	Cancers (Basel)	2020
31965074	Therapy-induced senescence - an induced synthetic lethality in liver cancer?	Nature Reviews Gastroenterology and Hepatology	2020
31954489	Novel patient-derived preclinical models of liver cancer.	Journal of Hepatology	2020
31830767	[Nuclear protein in testis (NUT) midline carcinoma].	RoFo Fortschritte auf dem Gebiet der Rontgenstrahlen und der Bildgebenden Verfahren	2020
31938815	[Personalized treatment of cholangiocellular carcinoma (CCA)].	Der Internist	2020
32165639	Cancer immune control needs senescence induction by interferon-dependent cell cycle regulator pathways in tumours.	Nat Commun	2020
32598967	Reduced mitochondrial resilience enables non-canonical induction of apoptosis after TNF receptor signaling in virus-infected hepatocytes.	J Hepatol	2020
32923905	Next-Generation Sequencing of Advanced GI Tumors Reveals Individual Treatment Options.	JCO Precis Oncol	2020
32640669	Influence of Biopsy Technique on Molecular Genetic Tumor Characterization in Non-Small Cell Lung Cancer-The Prospective, Randomized, Single-Blinded, Multicenter PROFILER Study Protocol.	Diagnostics (Basel)	2020
33134924	Experimental glioma with high bHLH expression harbor increased replicative stress and are sensitive toward ATR inhibition.	Neurooncol Adv	2020
30936549	Platelet GPIbÎ± is a mediator and potential interventional target for NASH and subsequent liver cancer.	Nat Med	2019
31799499	Cardiac glycosides are broad-spectrum senolytics.	Nature Metabolism	2019
31754005	Peritumoral activation of the Hippo pathway effectors YAP and TAZ suppresses liver cancer in mice.	Science	2019