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Author Details

Christian M T Spahn
Institut fur Medizinische Physik und Biophysik, Charite-Universitatsmedizin Berlin
1990
103
47
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36762436Structural mechanism of CRL4-instructed STAT2 degradation via a novel cytomegaloviral DCAF receptor.EMBO J2023
37156858Structure of the actively translating plant 80S ribosome at 2.2⿿ÿ resolution.Nat Plants2023
37361875A nanobody recognizes a unique conserved epitope and potently neutralizes SARS-CoV-2 omicron variants.iScience2023
36797249Cryo-EM captures early ribosome assembly in action.Nat Commun2023
36496453Cryo-electron tomography reveals structural insights into the membrane remodeling mode of dynamin-like EHD filaments.Nat Commun2022
35709277Structure of the mammalian ribosome as it decodes the selenocysteine UGA codon.Science2022
33357414Protein Synthesis in the Developing Neocortex at Near-Atomic Resolution Reveals Ebp1-Mediated Neuronal Proteostasis at the 60S Tunnel Exit.Mol Cell2021
33639093Snapshots of native pre-50S ribosomes reveal a biogenesis factor network and evolutionary specialization.Mol Cell2021
34561620Structures of active melanocortin-4 receptor-Gs-protein complexes with NDP-α-MSH and setmelanotide.Cell Res2021
34339457Structural insights into Cullin4-RING ubiquitin ligase remodelling by Vpr from simian immunodeficiency viruses.PLoS Pathog2021
34234344Structural basis of early translocation events on the ribosome.Nature2021
33139728Divergent architecture of the heterotrimeric NatC complex explains N-terminal acetylation of cognate substrates.Nat Commun2020
31856152Insights into the assembly and activation of the microtubule nucleator γ-TuRC.Nature2020
32092125Cryo-EM structure of the Shigella type III needle complex.PLoS Pathog2020
30626072Translatomics: The Global View of Translation.Int J Mol Sci2019
31722215The Axonal Membrane Protein PRG2 Inhibits PTEN and Directs Growth to Branches.Cell Rep2019
31178895Multifaceted Stoichiometry Control of Bacterial Operons Revealed by Deep Proteome Quantification.Front Genet2019
31155236Alanine Tails Signal Proteolysis in Bacterial Ribosome-Associated Quality Control.Cell2019
30795892Structural Basis for the Action of an All-Purpose Transcription Anti-termination Factor.Mol Cell2019
29311697Mechanistic insights into the role of prenyl-binding protein PrBP/δ in membrane dissociation of phosphodiesterase 6.Nat Commun2018
29883607Structural Visualization of the Formation and Activation of the 50S Ribosomal Subunit during In Vitro Reconstitution.Mol Cell2018
30068566It takes two transducins to activate the cGMP-phosphodiesterase 6 in retinal rods.Open Biol2018
30517857tRNA Translocation by the Eukaryotic 80S Ribosome and the Impact of GTP Hydrolysis.Cell Rep2018
29788317FragFit: a web-application for interactive modeling of protein segments into cryo-EM density maps.Nucleic Acids Res2018
28576440Photometric assay of maltose and maltose-forming enzyme activity by using 4-alpha-glucanotransferase (DPE2) from higher plants.Anal Biochem2017
28452979Structural basis for λN-dependent processive transcription antitermination.Nat Microbiol2017
28684008Ribosomal Chamber Music: Toward an Understanding of IRES Mechanisms.Trends Biochem Sci2017
26973877Structures of ribosome-bound initiation factor 2 reveal the mechanism of subunit association.Sci Adv2016
27995908Structural insights into ribosomal rescue by Dom34 and Hbs1 at near-atomic resolution.Nat Commun2016
27273634Knud Hermann Nierhaus 1941-2016.Nat Struct Mol Biol2016
27234690Ribosomes Structure and Mechanisms in Regulation of Protein Synthesis Part I.J Mol Biol2016
27521698Editorial.J Mol Biol2016
25601755Cryo-EM of ribosomal 80S complexes with termination factors reveals the translocated cricket paralysis virus IRES.Mol Cell2015
26604301Molecular architecture of the ribosome-bound Hepatitis C Virus internal ribosomal entry site RNA.EMBO J2015
26068751Using Molecular Simulation to Model High-Resolution Cryo-EM Reconstructions.Methods Enzymol2015
25957688Structural snapshots of actively translating human ribosomes.Cell2015
25658201Ribosome rescue and protein quality control in concert.Mol Cell2015
24362468EF-G and EF4: translocation and back-translocation on the bacterial ribosome.Nat Rev Microbiol2014
25064512Structure of the mammalian 80S initiation complex with initiation factor 5B on HCV-IRES RNA.Nat Struct Mol Biol2014
24995983Regulation of the mammalian elongation cycle by subunit rolling: a eukaryotic-specific ribosome rearrangement.Cell2014
24508342Structural insights into membrane interaction and caveolar targeting of dynamin-like EHD2.Structure2014
24562077CTER-rapid estimation of CTF parameters with error assessment.Ultramicroscopy2014
24524803A new system for naming ribosomal proteins.Curr Opin Struct Biol2014
24324168Visualization of two transfer RNAs trapped in transit during elongation factor G-mediated translocation.Proc Natl Acad Sci U S A2013
22622583The complex of tmRNA-SmpB and EF-G on translocating ribosomes.Nature2012
21378123Structural basis for the binding of IRES RNAs to the head of the ribosomal 40S subunit.Nucleic Acids Res2011
22002606The crystal structure of an oxygen-tolerant hydrogenase uncovers a novel iron-sulphur centre.Nature2011
22080606Excited states of ribosome translocation revealed through integrative molecular modeling.Proc Natl Acad Sci U S A2011
22078558Identifying conformational states of macromolecules by eigen-analysis of resampled cryo-EM images.Structure2011
22017870Structure and dynamics of the mammalian ribosomal pretranslocation complex.Mol Cell2011
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Collaborators

Joachim Frank
Columbia University
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Pawel A Penczek
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Co-authored papers 20
Roland Beckmann
University of Munich
Co-authored papers 8
Rajendra K Agrawal
School of Public Health, University at Albany
Co-authored papers 6
G??nter Blobel
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Co-authored papers 3
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University of California San Francisco
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University of Massachusetts Chan Medical School
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University of California at San Francisco
Co-authored papers 2
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Institute for Biotechnology, Technical University Berlin
Co-authored papers 2
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University of Illinois at Chicago
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Howard Hughes Medical Institute, Inc. at the Wadsworth Center
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University of California San Diego
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Howard Hughes Medical Institute, The Rockefeller University
Co-authored papers 1
Peter Sarnow
Stanford University School of Medicine
Co-authored papers 1
Denis L J Lafontaine
Universite libre de Bruxelles (ULB)
Co-authored papers 1
Henning Urlaub
Max Planck Institute for Multidisciplinary Sciences
Co-authored papers 1
Simon Anders
Heidelberg University
Co-authored papers 1
Yifan Cheng
Quantitative Bioscience Institute, University of California san francisco
Co-authored papers 1
Uwe Ohler
Humboldt University
Co-authored papers 1
Dmitri I Svergun
King's College London BHF Centre for Research Excellence
Co-authored papers 1
Maya Topf
Leibniz-Institut fur Virologie (LIV)
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Keith J Chappell
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