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Author Details
Full Name
Timothy J McMahon
Affiliation
Duke University Health System
ORCID
Career Start Year
1991
Papers
77
H Index
26
Expertise
CM4AI Collaborator
PMID
Paper Title
Journal Title
Published Year
36296435
Design, Synthesis, and Investigation of Novel Nitric Oxide (NO)-Releasing Aromatic Aldehydes as Drug Candidates for the Treatment of Sickle Cell Disease.
Molecules
2022
33449849
Pannexin 1 channels control the hemodynamic response to hypoxia by regulating O<sub>2</sub>-sensitive extracellular ATP in blood.
Am J Physiol Heart Circ Physiol
2021
32203007
Effects of repleting organic phosphates in banked erythrocytes on plasma metabolites and vasoactive mediators after red cell exchange transfusion in sickle cell disease.
Blood Transfus
2020
32576698
HGT in the human and skin commensal <i>Malassezia</i>: A bacterially derived flavohemoglobin is required for NO resistance and host interaction.
Proc Natl Acad Sci U S A
2020
31484636
Nitric oxide loading reduces sickle red cell adhesion and vaso-occlusion in vivo.
Blood Adv
2019
29243830
Proceedings of the Food and Drug Administration's public workshop on new red blood cell product regulatory science 2016.
Transfusion
2018
29931051
Drebrin regulates angiotensin II-induced aortic remodelling.
Cardiovasc Res
2018
30576340
Red blood cell phenotype fidelity following glycerol cryopreservation optimized for research purposes.
PLoS One
2018
29025575
Biomarkers in Pulmonary Vascular Disease: Gauging Response to Therapy.
Am J Cardiol
2017
28382373
Antagonists of the system L neutral amino acid transporter (LAT) promote endothelial adhesivity of human red blood cells.
Thromb Haemost
2017
27060546
S-Nitrosylated fetal hemoglobin in neonatal human blood.
Biochem Biophys Res Commun
2016
25611885
Treatment-related biomarkers in pulmonary hypertension.
Am J Respir Cell Mol Biol
2015
26542252
Platelets promote pulmonary pull of polys.
Blood
2015
26098062
Renitrosylation of banked human red blood cells improves deformability and reduces adhesivity.
Transfusion
2015
25766567
Liberation of ATP secondary to hemolysis is not mutually exclusive of regulated export.
Blood
2015
24735194
Randomized study of washing 40- to 42-day-stored red blood cells.
Transfusion
2014
25305182
Restoration of intracellular ATP production in banked red blood cells improves inducible ATP export and suppresses RBC-endothelial adhesion.
Am J Physiol Heart Circ Physiol
2014
23161885
Automated measurement of blood flow velocity and direction and hemoglobin oxygen saturation in the rat lung using intravital microscopy.
Am J Physiol Lung Cell Mol Physiol
2013
23827235
Parallel assay of oxygen equilibria of hemoglobin.
Anal Biochem
2013
23438482
Proteomic analysis of the NOS2 interactome in human airway epithelial cells.
Nitric Oxide
2013
21907348
Inhaled nitric oxide therapy increases blood nitrite, nitrate, and s-nitrosohemoglobin concentrations in infants with pulmonary hypertension.
J Pediatr
2012
22452273
Impact of transfusion of autologous 7- versus 42-day-old AS-3 red blood cells on tissue oxygenation and the microcirculation in healthy volunteers.
Transfusion
2012
22550218
The opprobrium of Big Tobacco.
Am J Respir Crit Care Med
2012
22323364
Transpulmonary flux of S-nitrosothiols and pulmonary vasodilation during nitric oxide inhalation: role of transport.
Am J Respir Cell Mol Biol
2012
20348208
Nitric oxide mediates relative airway hyporesponsiveness to lipopolysaccharide in surfactant protein A-deficient mice.
Am J Respir Cell Mol Biol
2011
21765360
Impaired adenosine-5'-triphosphate release from red blood cells promotes their adhesion to endothelial cells: a mechanism of hypoxemia after transfusion.
Crit Care Med
2011
20423728
Transport rather than diffusion-dependent route for nitric oxide gas activity in alveolar epithelium.
Free Radic Biol Med
2010
18441097
Pulmonary alveolar epithelial uptake of S-nitrosothiols is regulated by L-type amino acid transporter.
Am J Physiol Lung Cell Mol Physiol
2008
17420301
Transport and peripheral bioactivities of nitrogen oxides carried by red blood cell hemoglobin: role in oxygen delivery.
Physiology (Bethesda)
2007
17940021
Evolution of adverse changes in stored RBCs.
Proc Natl Acad Sci U S A
2007
16391304
Physician subsidies for tobacco advertising.
Am J Respir Crit Care Med
2006
16891657
Excitation-contraction coupling in airway smooth muscle.
J Biol Chem
2006
16565424
Extrapulmonary effects of inhaled nitric oxide: role of reversible S-nitrosylation of erythrocytic hemoglobin.
Proc Am Thorac Soc
2006
16126786
S-nitrosoglutathione inhibits alpha1-adrenergic receptor-mediated vasoconstriction and ligand binding in pulmonary artery.
Am J Physiol Lung Cell Mol Physiol
2006
15879309
Oxygen regulation of tumor perfusion by S-nitrosohemoglobin reveals a pressor activity of nitric oxide.
Circ Res
2005
16203976
A nitric oxide processing defect of red blood cells created by hypoxia: deficiency of S-nitrosohemoglobin in pulmonary hypertension.
Proc Natl Acad Sci U S A
2005
16148069
A novel inhaled organic nitrate that affects pulmonary vascular tone in a piglet model of hypoxia-induced pulmonary hypertension.
Pediatr Res
2005
16373824
Redox activation of intracellular calcium release channels (ryanodine receptors) in the sustained phase of hypoxia-induced pulmonary vasoconstriction.
Chest
2005
15824313
Hemoglobin conformation couples erythrocyte S-nitrosothiol content to O2 gradients.
Proc Natl Acad Sci U S A
2005
14980227
Essential roles of S-nitrosothiols in vascular homeostasis and endotoxic shock.
Cell
2004
12727142
S-nitrosylation in health and disease.
Trends Mol Med
2003
12879896
Hemoglobin and nitric oxide.
N Engl J Med
2003
12814919
S-nitrosohemoglobin is distinguished from other nitrosovasodilators by unique oxygen-dependent responses that support an allosteric mechanism of action.
Blood
2003
11943671
Pulmonary vasoconstriction by serotonin is inhibited by S-nitrosoglutathione.
Am J Physiol Lung Cell Mol Physiol
2002
12042776
Nitric oxide in the human respiratory cycle.
Nat Med
2002
11320213
S-nitrosothiol repletion by an inhaled gas regulates pulmonary function.
Proc Natl Acad Sci U S A
2001
10747928
Functional coupling of oxygen binding and vasoactivity in S-nitrosohemoglobin.
J Biol Chem
2000
9919558
Concerted nitric oxide/oxygen delivery by hemoglobin.
Methods Enzymol
1999
9799212
In vivo gene transfer of nitric oxide synthase enhances vasomotor function in carotid arteries from normal and cholesterol-Fed rabbits.
Circulation
1998
9643794
Bronchodilator S-nitrosothiol deficiency in asthmatic respiratory failure.
Lancet
1998
1 - 50 of 77
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Center for Blood Oxygen Transport and Hemostasis, University of Maryland
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Marilyn J Telen
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Renaissance School of Medicine at Stony, Brook University
Co-authored papers
3
Robert M Califf
From the National Institutes of Health
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University of Colorado Anschutz Medical Campus
Co-authored papers
2
Andrew J Ghio
Co-authored papers
2
Michael P Busch
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Co-authored papers
1
James C Zimring
University of Virginia
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1
Jennifer A Muszynski
0Nationwide Children's Hospital
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1
John R Hess
Harborview Medical Center
Co-authored papers
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University of California
Co-authored papers
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Thomas L Ortel
Duke University Medical Center
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1
Philip C Spinella
Pittsburgh University
Co-authored papers
1
Peter J Myler
University of Guelph
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1
Philip J Norris
Vitalant Research Institute
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William D White
The Royal London Hospital, West Hertfordshire Teaching Hospitals NHS Trust
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Martin A Moseley
Center for Genomic and Computational Biology
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1
Harvey G Klein
Clinical Center, National Institutes of Health
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Michael A Dubick
United States Army Institute of Surgical Research
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1
Paul M Ness
Johns Hopkins University
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1
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