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Author Details

Wolf Reik
The Babraham Institute
1985
293
118
Emma Lundberg (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37356343Human 8-cell embryo-like cells from pluripotent stem cells.Curr Opin Genet Dev2023
37774033Epigenetic dynamics during capacitation of naïve human pluripotent stem cells.Sci Adv2023
37322154Direct methylation sequencing.Nat Chem Biol2023
37121869Mitigating age-related somatic mutation burden.Trends Mol Med2023
37239317Embryonic Stem Cell-Derived Neurons as a Model System for Epigenome Maturation during Development.Genes (Basel)2023
34489600Integration of spatial and single-cell transcriptomic data elucidates mouse organogenesis.Nat Biotechnol2022
35709828Spatial profiling of early primate gastrulation in utero.Nature2022
35475220A comprehensive approach for genome-wide efficiency profiling of DNA modifying enzymes.Cell Rep Methods2022
35439430Amniogenesis occurs in two independent waves in primates.Cell Stem Cell2022
35534560DNMT3A binds ubiquitinated histones to regulate bivalent genes.Nat Genet2022
36473463Comparative Principles of DNA Methylation Reprogramming during Human and Mouse In Vitro Primordial Germ Cell Specification.Dev Cell2022
36044898Self-organization of plasticity and specialization in a primitively social insect.Cell Syst2022
36163261Single-cell multi-omics profiling links dynamic DNA methylation to cell fate decisions during mouse early organogenesis.Genome Biol2022
35948369Single-cell multi-omics of human preimplantation embryos shows susceptibility to glucocorticoids.Genome Res2022
352166718C-like cells capture the human zygotic genome activation program in vitro.Cell Stem Cell2022
35235716Multi-omic rejuvenation of naturally aged tissues by a single cycle of transient reprogramming.Aging Cell2022
33024290Active turnover of DNA methylation during cell fate decisions.Nat Rev Genet2021
33542322Histone modifications form a cell-type-specific chromosomal bar code that persists through the cell cycle.Sci Rep2021
33899013Pooled CRISPR-activation screening coupled with single-cell RNA-seq in mouse embryonic stem cells.STAR Protoc2021
33731935Publisher Correction: LifeTime and improving European healthcare through cell-based interceptive medicine.Nature2021
34931676Maternal Dppa2 and Dppa4 are dispensable for zygotic genome activation but important for offspring survival.Development2021
34599190Enhancer-associated H3K4 methylation safeguards in vitro germline competence.Nat Commun2021
32251294Low rates of mutation in clinical grade human pluripotent stem cells under different culture conditions.Nat Commun2020
31919574Correction to: Tet3 regulates cellular identity and DNA methylation in neural progenitor cells.Cell Mol Life Sci2020
33125370Transcriptome and epigenome diversity and plasticity of muscle stem cells following transplantation.PLoS Genet2020
32718321DNA methylation repels binding of hypoxia-inducible transcription factors to maintain tumor immunotolerance.Genome Biol2020
32634384A Single-Cell Transcriptomics CRISPR-Activation Screen Identifies Epigenetic Regulators of the Zygotic Genome Activation Program.Cell Syst2020
32572255Epigenetic priming by Dppa2 and 4 in pluripotency facilitates multi-lineage commitment.Nat Struct Mol Biol2020
32894860LifeTime and improving European healthcare through cell-based interceptive medicine.Nature2020
30692203Dppa2 and Dppa4 directly regulate the Dux-driven zygotic transcriptional program.Genes Dev2019
31767039DNA methylation aging clocks: challenges and recommendations.Genome Biol2019
31562479Voices in methods development.Nat Methods2019
31554804Ageing affects DNA methylation drift and transcriptional cell-to-cell variability in mouse muscle stem cells.Nat Commun2019
31409373Screening for genes that accelerate the epigenetic aging clock in humans reveals a role for the H3K36 methyltransferase NSD1.Genome Biol2019
31422912Distinct Molecular Trajectories Converge to Induce Naive Pluripotency.Cell Stem Cell2019
30744673Combined single-cell profiling of expression and DNA methylation reveals splicing regulation and heterogeneity.Genome Biol2019
30979904TET3 prevents terminal differentiation of adult NSCs by a non-catalytic action at Snrpn.Nat Commun2019
30795792Correction to: Comparison of whole-genome bisulfite sequencing library preparation strategies identifies sources of biases affecting DNA methylation data.Genome Biol2019
30787436A single-cell molecular map of mouse gastrulation and early organogenesis.Nature2019
31160711Establishment of porcine and human expanded potential stem cells.Nat Cell Biol2019
30604745The non-canonical SMC protein SmcHD1 antagonises TAD formation and compartmentalisation on the inactive X chromosome.Nat Commun2019
30673604Transcriptional Heterogeneity in Naive and Primed Human Pluripotent Stem Cells at Single-Cell Resolution.Cell Rep2019
29686419Dynamics of the epigenetic landscape during the maternal-to-zygotic transition.Nat Rev Mol Cell Biol2018
29988127Cold-induced epigenetic programming of the sperm enhances brown adipose tissue activity in the offspring.Nat Med2018
30087436Publisher Correction: Cold-induced epigenetic programming of the sperm enhances brown adipose tissue activity in the offspring.Nat Med2018
30087435Author Correction: Cold-induced epigenetic programming of the sperm enhances brown adipose tissue activity in the offspring.Nat Med2018
30031774Genome-Scale Oscillations in DNA Methylation during Exit from Pluripotency.Cell Syst2018
30462643Hepatic gene body hypermethylation is a shared epigenetic signature of murine longevity.PLoS Genet2018
303491375-Formylcytosine organizes nucleosomes and forms Schiff base interactions with histones in mouse embryonic stem cells.Nat Chem2018
30315171Transgenerational transmission of hedonic behaviors and metabolic phenotypes induced by maternal overnutrition.Transl Psychiatry2018
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Collaborators

Co-authored papers 28
The Gurdon Institute
Co-authored papers 20
Wellcome Sanger Institute
Co-authored papers 14
University of Cambridge
Co-authored papers 9
Cancer Research UK Cambridge Institute, University of Cambridge
Co-authored papers 9
Co-authored papers 8
Co-authored papers 6
Medical University of Vienna
Co-authored papers 5
European Bioinformatics Institute (EMBL-EBI)
Co-authored papers 4
Wellcome Sanger Institute
Co-authored papers 4
Weizmann Institute of Science
Co-authored papers 4
KU Leuven Institute for Single Cell Omics (LISCO)
Co-authored papers 4
Co-authored papers 4
Co-authored papers 3
Karolinska Institute
Co-authored papers 3
UCL Cancer Institute, University College London
Co-authored papers 3
CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
Co-authored papers 3
Technical University of Munich
Co-authored papers 3
Josep Carreras Leukaemia Research Institute (IJC)
Co-authored papers 3
Co-authored papers 3
Weizmann Institute of Science
Co-authored papers 3
The University of Edinburgh
Co-authored papers 3
Institute of Epigenetics and Stem Cells (IES)
Co-authored papers 3
Princess Maxima Center for Pediatric Oncology
Co-authored papers 3
Institute for Medical Engineering & Science, Massachusetts Institute of Technology
Co-authored papers 2
Co-authored papers 2
Leiden University Medical Center
Co-authored papers 2
Stanford University School of Medicine
Co-authored papers 2
Max Delbruck Center for Molecular Medicine in the Helmholtz Association (MDC)
Co-authored papers 2
Brigham and Women's Hospital
Co-authored papers 2