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Author Details

Clare Jolly
University College London
2000
46
25
Kirsten Obernier (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36693093SARS-CoV-2 evolution influences GBP and IFITM sensitivity.Proc Natl Acad Sci U S A2023
35165389Executable network of SARS-CoV-2-host interaction predicts drug combination treatments.NPJ Digit Med2022
35999696Evolutionary remodelling of N-terminal domain loops fine-tunes SARS-CoV-2 spike.EMBO Rep2022
35012962Preclinical and randomized phase I studies of plitidepsin in adults hospitalized with COVID-19.Life Sci Alliance2022
34942634Evolution of enhanced innate immune evasion by SARS-CoV-2.Nature2022
35332335Publisher Correction: Evolution of enhanced innate immune evasion by SARS-CoV-2.Nature2022
35062333A Conserved Tryptophan in the Envelope Cytoplasmic Tail Regulates HIV-1 Assembly and Spread.Viruses2022
33299142SARS-CoV-2 antibody responses in patients with acute leukaemia.Leukemia2021
33791702Characterisation of B.1.1.7 and Pangolin coronavirus spike provides insights on the evolutionary trajectory of SARS-CoV-2.bioRxiv2021
34075384Plitidepsin has a positive therapeutic index in adult patients with COVID-19 requiring hospitalization.medRxiv2021
33990561Targeting human Acyl-CoA:cholesterol acyltransferase as a dual viral and T cell metabolic checkpoint.Nat Commun2021
34127972Evolution of enhanced innate immune evasion by the SARS-CoV-2 B.1.1.7 UK variant.bioRxiv2021
34101213SARS-CoV-2 sensing by RIG-I and MDA5 links epithelial infection to macrophage inflammation.EMBO J2021
34001619HIV envelope tail truncation confers resistance to SERINC5 restriction.Proc Natl Acad Sci U S A2021
32179688Loss of Nef-mediated CD3 down-regulation in the HIV-1 lineage increases viral infectivity and spread.Proc Natl Acad Sci U S A2020
33144375<i>In Vivo</i> Emergence of a Novel Protease Inhibitor Resistance Signature in HIV-1 Matrix.mBio2020
28122231HIV-1 Activates T Cell Signaling Independently of Antigen to Drive Viral Spread.Cell Rep2017
28141491Combination antiretroviral therapy and cell-cell spread of wild-type and drug-resistant human immunodeficiency virus-1.J Gen Virol2017
27558417LFA-1 Engagement Triggers T Cell Polarization at the HIV-1 Virological Synapse.J Virol2016
25320323Contact-induced mitochondrial polarization supports HIV-1 virological synapse formation.J Virol2015
25837979Hybrid spreading mechanisms and T cell activation shape the dynamics of HIV-1 infection.PLoS Comput Biol2015
25393110Retromer regulates HIV-1 envelope glycoprotein trafficking and incorporation into virions.PLoS Pathog2014
25700025Neutralisation of HIV-1 cell-cell spread by human and llama antibodies.Retrovirology2014
23884583Attachment factors.Adv Exp Med Biol2013
24364896Protease inhibitors effectively block cell-to-cell spread of HIV-1 between T cells.Retrovirology2013
24047317Immune adaptor ADAP in T cells regulates HIV-1 transcription and cell-cell viral spread via different co-receptors.Retrovirology2013
20382227Optimized methods for imaging membrane nanotubes between T cells and trafficking of HIV-1.Methods2011
21909273The regulated secretory pathway in CD4(+) T cells contributes to human immunodeficiency virus type-1 cell-to-cell spread at the virological synapse.PLoS Pathog2011
21901095Transportin 3 promotes a nuclear maturation step required for efficient HIV-1 integration.PLoS Pathog2011
21247613Cell-to-cell transmission of retroviruses: Innate immunity and interferon-induced restriction factors.Virology2011
20089656Virological synapse-mediated spread of human immunodeficiency virus type 1 between T cells is sensitive to entry inhibition.J Virol2010
21994679T cell polarization at the virological synapse.Viruses2010
20861257Cell-cell spread of human immunodeficiency virus type 1 overcomes tetherin/BST-2-mediated restriction in T cells.J Virol2010
20181695SDF-1/CXCL12 production by mature dendritic cells inhibits the propagation of X4-tropic HIV-1 isolates at the dendritic cell-T-cell infectious synapse.J Virol2010
18193035Membrane nanotubes physically connect T cells over long distances presenting a novel route for HIV-1 transmission.Nat Cell Biol2008
17360745Requirement for an intact T-cell actin and tubulin cytoskeleton for efficient assembly and spread of human immunodeficiency virus type 1.J Virol2007
17962070Regulated secretion from CD4+ T cells.Trends Immunol2007
17913807Adhesion molecule interactions facilitate human immunodeficiency virus type 1-induced virological synapse formation between T cells.J Virol2007
17522207Human immunodeficiency virus type 1 assembly, budding, and cell-cell spread in T cells take place in tetraspanin-enriched plasma membrane domains.J Virol2007
16140785Human immunodeficiency virus type 1 virological synapse formation in T cells requires lipid raft integrity.J Virol2005
14734528HIV-1 cell to cell transfer across an Env-induced, actin-dependent synapse.J Exp Med2004
15296489Retroviral spread by induction of virological synapses.Traffic2004
11556708Non-lytic extraction and characterisation of receptors for multiple strains of rotavirus.Arch Virol2001
11543883Selection of rotavirus VP4 cell receptor binding domains for MA104 cells using a phage display library.J Virol Methods2001
11563928Synthesis and biological evaluation of sialylmimetics as rotavirus inhibitors.J Med Chem2001
11017790Rotavirus infection of MA104 cells is inhibited by Ricinus lectin and separately expressed single binding domains.Virology2000
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Collaborators

University College London
Co-authored papers 10
University College London
Co-authored papers 10
University College London
Co-authored papers 9
J. David Gladstone Institutes
Co-authored papers 6
University of California San Francisco
Co-authored papers 5
J. David Gladstone Institutes
Co-authored papers 5
Icahn School of Medicine at Mount Sinai
Co-authored papers 5
University of California San Francisco
Co-authored papers 5
University College London
Co-authored papers 5
University College London
Co-authored papers 4
Icahn School of Medicine at Mount Sinai
Co-authored papers 4
Quantitative Biosciences Institute (QBI) Coronavirus Research Group (QCRG)
Co-authored papers 4
University College London
Co-authored papers 4
University of Cambridge
Co-authored papers 3
Institute of Molecular Systems Biology, ETH Zurich
Co-authored papers 3
University of Cambridge, Addenbrooke's Hospital Level 5
Co-authored papers 3
University of California, San Francisco
Co-authored papers 3
Cardiovascular Research Institute, University of California San Francisco
Co-authored papers 3
J. David Gladstone Institutes
Co-authored papers 3
Fred Hutchinson Cancer Center
Co-authored papers 3
University of Ottawa
Co-authored papers 3
J. David Gladstone Institutes
Co-authored papers 3
University of California, University of California San Francisco
Co-authored papers 3
University College London
Co-authored papers 3
J. David Gladstone Institutes
Co-authored papers 3
University of Wisconsin-Madison
Co-authored papers 3
University of Cambridge
Co-authored papers 3
University of California San Francisco
Co-authored papers 3
University of California San Francisco
Co-authored papers 3
European Bioinformatics Institute
Co-authored papers 3