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Author Details

Levon M Khachigian
University of New South Wales
1991
221
56
PMIDPaper TitleJournal TitlePublished Year
36908666TCF7L1 Exacerbates Abdominal Aortic Aneurysm Prevalence and Severity.JACC Basic Transl Sci2023
37511453Immune Checkpoint Inhibitors, Small-Molecule Immunotherapies and the Emerging Role of Neutrophil Extracellular Traps in Therapeutic Strategies for Head and Neck Cancer.Int J Mol Sci2023
37734428The MEK-ERK-Egr-1 axis and its regulation in cardiovascular disease.Vascul Pharmacol2023
37024319Early Growth Response-1: Friend or Foe in the Heart?Heart Lung Circ2023
37452307Flubendazole inhibits PD-1 and suppresses melanoma growth in immunocompetent mice.J Transl Med2023
37312148Translating discoveries as novel biomarkers and interventions in ophthalmology.J Transl Med2023
37128915Gene Therapeutic Strategies for Peripheral Artery Disease and New Opportunities Provided by Adeno-Associated Virus Vectors.Arterioscler Thromb Vasc Biol2023
36813495Proportion of people with diabetic retinopathy and macular oedema varies by ethnicity in a tertiary retinal clinic in Australia: findings from the Liverpool Eye and Diabetes Study (LEADS).BMJ Open2023
36810060Emerging therapeutic strategies for unmet need in neovascular age-related macular degeneration.J Transl Med2023
35041980RNA sequencing identifies genes reliant upon Ser26 in the zinc finger transcription factor, early growth response-1.Vascul Pharmacol2022
35896140Transcriptional regulation of vascular smooth muscle cell proliferation, differentiation and senescence: Novel targets for therapy.Vascul Pharmacol2022
34476983Serine 26 in Early Growth Response-1 Is Critical for Endothelial Proliferation, Migration, and Network Formation.J Am Heart Assoc2021
33790617BT2 Suppresses Human Monocytic-Endothelial Cell Adhesion, Bone Erosion and Inflammation.J Inflamm Res2021
33508088Truncated YY1 interacts with BASP1 through a 339KLK341 motif in YY1 and suppresses vascular smooth muscle cell growth and intimal hyperplasia after vascular injury.Cardiovasc Res2021
34520820Emerging insights on functions of the anthelmintic flubendazole as a repurposed anticancer agent.Cancer Lett2021
34755520Early Growth Response-1, an Integrative Sensor in Cardiovascular and Inflammatory Disease.J Am Heart Assoc2021
32325020Pharmaceutical patents: reconciling the human right to health with the incentive to invent.Drug Discov Today2020
31858902Repurposing Drugs for Skin Cancer.Curr Med Chem2020
33328478Neutralizing the pathological effects of extracellular histones with small polyanions.Nat Commun2020
32718981Comparative transcriptomics of primary cells in vertebrates.Genome Res2020
32798552Recruitment and maturation of the coronary collateral circulation: Current understanding and perspectives in arteriogenesis.Microvasc Res2020
32923607Thermostable small-molecule inhibitor of angiogenesis and vascular permeability that suppresses a pERK-FosB/οFosB-VCAM-1 axis.Sci Adv2020
32121587Remote Ischemic Preconditioning induces Cardioprotective Autophagy and Signals through the IL-6-Dependent JAK-STAT Pathway.Int J Mol Sci2020
30719216Circulating mediators of remote ischemic preconditioning: search for the missing link between non-lethal ischemia and cardioprotection.Oncotarget2019
31683712Transcription Factors Targeted by miRNAs Regulating Smooth Muscle Cell Growth and Intimal Thickening after Vascular Injury.Int J Mol Sci2019
31128215The anthelmintic flubendazole blocks human melanoma growth and metastasis and suppresses programmed cell death protein-1 and myeloid-derived suppressor cell accumulation.Cancer Lett2019
30711252Extracellular signal-regulated kinase-1 phosphorylates early growth response-1 at serine 26.Biochem Biophys Res Commun2019
30760521Deoxyribozymes as Catalytic Nanotherapeutic Agents.Cancer Res2019
29322514The Yin and Yang of YY1 in tumor growth and suppression.Int J Cancer2018
30177712Promoter Usage and Dynamics in Vascular Smooth Muscle Cells Exposed to Fibroblast Growth Factor-2 or Interleukin-1β.Sci Rep2018
29844573Melanoma protective antitumor immunity activated by catalytic DNA.Oncogene2018
30593535Withdrawal: c-Jun regulates shear- and injury-inducible Egr-1 expression, vein graft stenosis after autologous end-to-side transplantation in rabbits, and intimal hyperplasia in human saphenous veins.J Biol Chem2018
29765563Targeted therapies in the management of locally advanced and metastatic pancreatic cancer: a systematic review.Oncotarget2018
29626152"Summer Shift": A Potential Effect of Sunshine on the Time Onset of ST-Elevation Acute Myocardial Infarction.J Am Heart Assoc2018
28521970Corrigendum to "The role of c-jun in PDTC-sensitive flow-dependent restenosis after angioplasty and stenting" [Atherosclerosis 194 (2) (2007) 364-371].Atherosclerosis2017
29242850Developing Neolignans as Proangiogenic Agents: Stereoselective Total Syntheses and Preliminary Biological Evaluations of the Four Guaiacylglycerol 8-<i>O</i>-4'-Coniferyl Ethers.ACS Omega2017
28850106FANTOM5 CAGE profiles of human and mouse samples.Sci Data2017
27057945MicroRNA miR-191 targets the zinc finger transcription factor Egr-1 and suppresses intimal thickening after carotid injury.Int J Cardiol2016
27379921Inhibition of intimal thickening after vascular injury with a cocktail of vascular endothelial growth factor and cyclic Arg-Gly-Asp peptide.Int J Cardiol2016
27251707Early growth response-1 in the pathogenesis of cardiovascular disease.J Mol Med (Berl)2016
25678556Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells.Science2015
26252146Corrigendum: Suppression of vascular permeability and inflammation by targeting of the transcription factor c-Jun.Nat Biotechnol2015
25885578Transcriptional dynamics reveal critical roles for non-coding RNAs in the immediate-early response.PLoS Comput Biol2015
24670764A promoter-level mammalian expression atlas.Nature2014
25280005PDGF-D expression is down-regulated by TGFβ in fibroblasts.PLoS One2014
24780373Regulatory roles of c-jun in H5N1 influenza virus replication and host inflammation.Biochim Biophys Acta2014
23116266EGFR and the complexity of receptor crosstalk in the cardiovascular system.Curr Mol Med2013
23886527Inhibition of vein graft stenosis with a c-jun targeting DNAzyme in a cationic liposomal formulation containing 1,2-dioleoyl-3-trimethylammonium propane (DOTAP)/1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE).Int J Cardiol2013
23902638Selective inhibition of the master regulator transcription factor Egr-1 with catalytic oligonucleotides reduces myocardial injury and improves left ventricular systolic function in a preclinical model of myocardial infarction.J Am Heart Assoc2013
24009229Regulation of vascular leak and recovery from ischemic injury by general and VE-cadherin-restricted miRNA antagonists of miR-27.Blood2013
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Collaborators

Drexel University
Co-authored papers 19
International Institute of Molecular and Cell Biology in Warsaw
Co-authored papers 6
RIKEN Center for Integrative Medical Sciences
Co-authored papers 6
RIKEN Center for Integrative Medical Sciences
Co-authored papers 6
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Co-authored papers 6
RIKEN Center for Integrative Medical Sciences
Co-authored papers 5
Center for Integrative Medical Sciences
Co-authored papers 5
University of New South Wales
Co-authored papers 5
RIKEN Center for Integrative Medical Sciences (IMS)
Co-authored papers 5
Telethon Kids Institute, University of Western Australia
Co-authored papers 5
Co-authored papers 4
University of New South Wales
Co-authored papers 4
Institute for Protein Research, Osaka University
Co-authored papers 4
Center for Integrative Medical Sciences
Co-authored papers 4
Saint John's Cancer Institute at Saint John's Health Center
Co-authored papers 4
RIKEN Center for Integrative Medical Sciences
Co-authored papers 4
Cerevance Ltd
Co-authored papers 4
RIKEN Center for Life Science Technologies
Co-authored papers 4
University of Copenhagen
Co-authored papers 3
University of British Columbia
Co-authored papers 3
Institute of Pharmaceutical Sciences, ETH Zurich
Co-authored papers 3
Nagoya City University Graduate School of Medical Sciences
Co-authored papers 3
Child and Family Research Institute, University of British Columbia
Co-authored papers 3
RIKEN Research Center for Allergy and Immunology
Co-authored papers 3
Yokohama National University
Co-authored papers 3
International Centre for Genetic Engineering and Biotechnology
Co-authored papers 3
Australian Institute for Bioengineering and Nanotechnology, University of Queensland
Co-authored papers 3
South African Medical Research Council (SAMRC), University of Cape Town
Co-authored papers 3
Tohoku University Graduate School of Medicine
Co-authored papers 3
Leiden University Medical Center
Co-authored papers 3