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Author Details

Jeffrey B Bonanno
Albert Einstein College of Medicine
1999
78
33
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37563206Author Correction: Cell-impermeable staurosporine analog targets extracellular kinases to inhibit HSV and SARS-CoV-2.Commun Biol2023
36245045Cell-impermeable staurosporine analog targets extracellular kinases to inhibit HSV and SARS-CoV-2.Commun Biol2022
34709351HVEM structures and mutants reveal distinct functions of binding to LIGHT and BTLA/CD160.J Exp Med2021
32349291Structures of FOX-4 Cephamycinase in Complex with Transition-State Analog Inhibitors.Biomolecules2020
33458462Characterization of the SARS-CoV-2 S Protein: Biophysical, Biochemical, Structural, and Antigenic Analysis.ACS Omega2020
32587972Characterization of the SARS-CoV-2 S Protein: Biophysical, Biochemical, Structural, and Antigenic Analysis.bioRxiv2020
32356520Structure of a single-chain H2A/H2B dimer.Acta Crystallogr F Struct Biol Commun2020
32207970A Binary Arginine Methylation Switch on Histone H3 Arginine 2 Regulates Its Interaction with WDR5.Biochemistry2020
32497097Mechanistic dissection of the PD-L1:B7-1 co-inhibitory immune complex.PLoS One2020
31230945Structural Basis of CD160:HVEM Recognition.Structure2019
31320588An essential bifunctional enzyme in <i>Mycobacterium tuberculosis</i> for itaconate dissimilation and leucine catabolism.Proc Natl Acad Sci U S A2019
29283551Mechanism and Structure of γ-Resorcylate Decarboxylase.Biochemistry2018
29867142Functional assignment of multiple catabolic pathways for D-apiose.Nat Chem Biol2018
30277746Substrate Profile of the Phosphotriesterase Homology Protein from Escherichia coli.Biochemistry2018
29581255Anti-CTLA-4 therapy requires an Fc domain for efficacy.Proc Natl Acad Sci U S A2018
29767960Comparison of Alicyclobacillus acidocaldarius o-Succinylbenzoate Synthase to Its Promiscuous N-Succinylamino Acid Racemase/ o-Succinylbenzoate Synthase Relatives.Biochemistry2018
29405700X-ray and EPR Characterization of the Auxiliary Fe-S Clusters in the Radical SAM Enzyme PqqE.Biochemistry2018
29261291Structures of the L27 Domain of Disc Large Homologue 1 Protein Illustrate a Self-Assembly Module.Biochemistry2018
28704043Structural Insights into Thioether Bond Formation in the Biosynthesis of Sactipeptides.J Am Chem Soc2017
28484017Structural basis for cancer immunotherapy by the first-in-class checkpoint inhibitor ipilimumab.Proc Natl Acad Sci U S A2017
28162953Molecular Architecture of the Major Membrane Ring Component of the Nuclear Pore Complex.Structure2017
28246174Stilbene epoxidation and detoxification in a <i>Photorhabdus luminescens</i>-nematode symbiosis.J Biol Chem2017
29167421Structural insights into substrate and inhibitor binding sites in human indoleamine 2,3-dioxygenase 1.Nat Commun2017
26714575Substrate Distortion and the Catalytic Reaction Mechanism of 5-Carboxyvanillate Decarboxylase.J Am Chem Soc2016
27806260Crystal Structure of the Complex of Human FasL and Its Decoy Receptor DcR3.Structure2016
25713080Histone H2A and H4 N-terminal tails are positioned by the MEP50 WD repeat protein for efficient methylation by the PRMT5 arginine methyltransferase.J Biol Chem2015
26202493Increased Heterologous Protein Expression in Drosophila S2 Cells for Massive Production of Immune Ligands/Receptors and Structural Analysis of Human HVEM.Mol Biotechnol2015
25855808Determinants of the CmoB carboxymethyl transferase utilized for selective tRNA wobble modification.Nucleic Acids Res2015
24872444Loss of quaternary structure is associated with rapid sequence divergence in the OSBS family.Proc Natl Acad Sci U S A2014
25087510Mechanistic basis for functional promiscuity in the TNF and TNF receptor superfamilies: structure of the LIGHT:DcR3 assembly.Structure2014
25139911Integrative structure-function mapping of the nucleoporin Nup133 suggests a conserved mechanism for membrane anchoring of the nuclear pore complex.Mol Cell Proteomics2014
23499021Structure, dynamics, evolution, and function of a major scaffold component in the nuclear pore complex.Structure2013
24367637Structural context of disease-associated mutations and putative mechanism of autoinhibition revealed by X-ray crystallographic analysis of the EZH2-SET domain.PLoS One2013
24060347Divergent evolution of ligand binding in the o-succinylbenzoate synthase family.Biochemistry2013
24056934Discovery of new enzymes and metabolic pathways by using structure and genome context.Nature2013
23676670Structure-guided discovery of the metabolite carboxy-SAM that modulates tRNA function.Nature2013
23451136Structure of the arginine methyltransferase PRMT5-MEP50 reveals a mechanism for substrate specificity.PLoS One2013
23535894Crystal structure of human Karyopherin β2 bound to the PY-NLS of Saccharomyces cerevisiae Nab2.J Struct Funct Genomics2013
230357851-methylthio-D-xylulose 5-phosphate methylsulfurylase: a novel route to 1-deoxy-D-xylulose 5-phosphate in Rhodospirillum rubrum.Biochemistry2012
23006625Cas5d processes pre-crRNA and is a member of a larger family of CRISPR RNA endonucleases.RNA2012
21365675Structure of the C-terminal domain of Saccharomyces cerevisiae Nup133, a component of the nuclear pore complex.Proteins2011
20943661Structural bases of PAS domain-regulated kinase (PASK) activation in the absence of activation loop phosphorylation.J Biol Chem2010
21070950Structural underpinnings of nitrogen regulation by the prototypical nitrogen-responsive transcriptional factor NrpR.Structure2010
20722448Pnictogen-hydride activation by (silox)3Ta (silox = (t)Bu3SiO); attempts to circumvent the constraints of orbital symmetry in N2 activation.Inorg Chem2010
20737437Structure of a putative BenF-like porin from Pseudomonas fluorescens Pf-5 at 2.6 A resolution.Proteins2010
19219566Target selection and annotation for the structural genomics of the amidohydrolase and enolase superfamilies.J Struct Funct Genomics2009
19857646Periplasmic domains of Pseudomonas aeruginosa PilN and PilO form a stable heterodimeric complex.J Mol Biol2009
19883118Computation-facilitated assignment of the function in the enolase superfamily: a regiochemically distinct galactarate dehydratase from Oceanobacillus iheyensis .Biochemistry2009
19426233Sequence, structure, function, immunity: structural genomics of costimulation.Immunol Rev2009
19251641Type VI secretion apparatus and phage tail-associated protein complexes share a common evolutionary origin.Proc Natl Acad Sci U S A2009
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Collaborators

Albert Einstein College of Medicine
Co-authored papers 49
The State University of New Jersey
Co-authored papers 40
Eli Lilly and Co.
Co-authored papers 16
Brookhaven National Laboratory
Co-authored papers 15
University of California San Francisco
Co-authored papers 12
Poornaprajna Institute of Scientific Research (PPISR)
Co-authored papers 10
New York University Grossman School of Medicine
Co-authored papers 7
Case Western Reserve University
Co-authored papers 7
New York University Grossman School of Medicine
Co-authored papers 7
Medical College of Wisconsin
Co-authored papers 6
University of California san francisco
Co-authored papers 6
NYU Langone Hospital - Brooklyn Brooklyn
Co-authored papers 6
Co-authored papers 6
Albert Einstein College of Medicine
Co-authored papers 5
Argonne National Laboratory
Co-authored papers 5
University of Illinois at Urbana-Champaign
Co-authored papers 5
New York SGX Research Center for Structural Genomics
Co-authored papers 5
Brookhaven National Laboratory
Co-authored papers 5
Albert Einstein College of Medicine
Co-authored papers 4
Korea Advanced Institute of Science and Technology (KAIST)
Co-authored papers 4
Department of Pharmaceutical Chemistry, University of California san francisco
Co-authored papers 4
University of California san francisco
Co-authored papers 4
Sunesis Pharmaceuticals, Inc. 395 Oyster Point Boulevard
Co-authored papers 4
Cue BioPharma Inc.
Co-authored papers 4
University of California san francisco
Co-authored papers 4
Texas A&M University, College Station
Co-authored papers 4
Albert Einstein College of Medicine
Co-authored papers 4
The Rockefeller University
Co-authored papers 4
Brookhaven National Laboratory
Co-authored papers 4
The Rockefeller University
Co-authored papers 4