Author details

Full Name

Solomon H Snyder

Affiliation

ORCID

Career Start Year

1960

Papers

1149

H Index

229

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37352848	Serine Racemase mediates subventricular zone neurogenesis via fatty acid metabolism.		2023
37216099	Loss of PI3k activity of inositol polyphosphate multikinase impairs PDK1-mediated AKT activation, cell migration, and intestinal homeostasis.	iScience	2023
37456841	Inositol polyphosphate multikinase modulates redox signaling through nuclear factor erythroid 2-related factor 2 and glutathione metabolism.		2023
36403160	A Novel Stereospecific Bioluminescent Assay for Detection of Endogenous d-Cysteine.	ACS Chemical Neuroscience	2022
35579952	Cystathionine Î³-lyase exacerbates Helicobacter pylori immunopathogenesis by promoting macrophage metabolic remodeling and activation.	JCI insight	2022
36009188	Mutant Huntingtin Derails Cysteine Metabolism in Huntington's Disease at Both Transcriptional and Post-Translational Levels.	Antioxidants	2022
35484375	Mammalian D-cysteine: A novel regulator of neural progenitor cell proliferation Mammalian D-cysteine: A novel regulator of neural progenitor cell proliferation\nEndogenous D-cysteine, the stereoisomer with rapid spontaneous in vitro racemization rate, has	BioEssays	2022
35412917	A high-affinity cocaine binding site associated with the brain acid soluble protein 1.	Proc Natl Acad Sci U S A	2022
35353626	Inositol hexakisphosphate kinase-2 non-catalytically regulates mitophagy by attenuating PINK1 signaling.	Proceedings of the National Academy of Sciences of the United States of America	2022
35921423	Identification of the NRF2 transcriptional network as a therapeutic target for trigeminal neuropathic pain.	Science advances	2022
35536885	Biliverdin reductase bridges focal adhesion kinase to Src to modulate synaptic signaling.	Science Signaling	2022
34556581	D-cysteine is an endogenous regulator of neural progenitor cell dynamics in the mammalian brain.	Proceedings of the National Academy of Sciences of the United States of America	2021
33472023	Designed PKC-targeting bryostatin analogs modulate innate immunity and neuroinflammation.	Cell Chemical Biology	2021
33598661	Quantitative measurement of reactive oxygen species in mouse brain slices.	STAR Protocols	2021
33547244	Inositol hexakisphosphate kinase-2 determines cellular energy dynamics by regulating creatine kinase-B.	Proceedings of the National Academy of Sciences of the United States of America	2021
33137711	Effects of hydrogen sulfide on mitochondrial function and cellular bioenergetics.	Redox Biology	2021
33187730	Signaling by cGAS-STING in Neurodegeneration, Neuroinflammation, and Aging.	Trends in Neurosciences	2021
33414501	Cocaine-induced locomotor stimulation involves autophagic degradation of the dopamine transporter.	Molecular Psychiatry	2021
33431651	Hydrogen sulfide is neuroprotective in Alzheimer's disease by sulfhydrating GSK3Î² and inhibiting Tau hyperphosphorylation.	Proceedings of the National Academy of Sciences of the United States of America	2021
34400495	Redox imbalance links COVID-19 and myalgic encephalomyelitis/chronic fatigue syndrome.	Proceedings of the National Academy of Sciences of the United States of America	2021
32727065	BVR-A Deficiency Leads to Autophagy Impairment through the Dysregulation of AMPK/mTOR Axis in the Brain-Implications for Neurodegeneration.	Antioxidants	2020
31914376	Selective Persulfide Detection Reveals Evolutionarily Conserved Antiaging Effects of S-Sulfhydration.		2020
32493776	The nonselective cation channel TRPV4 inhibits angiotensin II receptors.	Journal of Biological Chemistry	2020
32822581	Inositol Pyrophosphates Mediate the DNA-PK/ATM-p53 Cell Death Pathway by Regulating CK2 Phosphorylation of Tti1/Tel2.	Mol Cell	2020
33115740	The inositol pyrophosphate 5-InsP<sub>7</sub> drives sodium-potassium pump degradation by relieving an autoinhibitory domain of PI3K p85Î±.	Sci Adv	2020
30941013	Impaired Redox Signaling in Huntington's Disease: Therapeutic Implications.	Frontiers in Molecular Neuroscience	2019
31735592	Selective Persulfide Detection Reveals Evolutionarily Conserved Antiaging Effects of S-Sulfhydration.		2019
31920936	Therapeutic Applications of Cysteamine and Cystamine in Neurodegenerative and Neuropsychiatric Diseases.	Frontiers in Neurology	2019
30007014	Regulators of the transsulfuration pathway.	British Journal of Pharmacology	2019
29634350	Redox Mechanisms in Neurodegeneration: From Disease Outcomes to Therapeutic Opportunities.	Antioxidants and Redox Signaling	2019
31278040	A Connective Tissue Mast-Cell-Specific Receptor Detects Bacterial Quorum-Sensing Molecules and Mediates Antibacterial Immunity.		2019
30692251	The glutathione cycle shapes synaptic glutamate activity.	Proceedings of the National Academy of Sciences of the United States of America	2019
30692248	Inositol polyphosphate multikinase mediates extinction of fear memory.	Proceedings of the National Academy of Sciences of the United States of America	2019
30910969	Histone H2AX promotes neuronal health by controlling mitochondrial homeostasis.	Proc Natl Acad Sci U S A	2019
31068464	MRGPRX4 is a G protein-coupled receptor activated by bile acids that may contribute to cholestatic pruritus.	Proceedings of the National Academy of Sciences of the United States of America	2019
31066329	Noncatalytic functions of IPMK are essential for activation of autophagy and liver regeneration.		2019
31353321	Bilirubin Links Heme Metabolism to Neuroprotection by Scavenging Superoxide.	Cell Chemical Biology	2019
30840891	IPMK Mediates Activation of ULK Signaling and Transcriptional Regulation of Autophagy Linked to Liver Inflammation and Regeneration.	Cell Rep	2019
30718399	Inositol hexakisphosphate kinase 3 promotes focal adhesion turnover via interactions with dynein intermediate chain 2.	Proceedings of the National Academy of Sciences of the United States of America	2019
28213892	Opportunities for the repurposing of PARP inhibitors for the therapy of non-oncological diseases.	Br J Pharmacol	2018
30006360	Inositol Hexakisphosphate Kinase-2 in Cerebellar Granule Cells Regulates Purkinje Cells and Motor Coordination via Protein 4.1N.	Journal of Neuroscience	2018
29670103	Histone H2AX deficiency causes neurobehavioral deficits and impaired redox homeostasis.	Nature Communications	2018
29530337	Cysteine Metabolism in Neuronal Redox Homeostasis.	Trends in Pharmacological Sciences	2018
29618559	Inhibition of IP6K1 suppresses neutrophil-mediated pulmonary damage in bacterial pneumonia.	Science Translational Medicine	2018
29440425	Bryostatin-1 alleviates experimental multiple sclerosis.	Proc Natl Acad Sci U S A	2018
29599194	Dimethyl fumarate targets GAPDH and aerobic glycolysis to modulate immunity.	Science	2018
29203369	Gasotransmitter hydrogen sulfide signaling in neuronal health and disease.	Biochemical Pharmacology	2018
29279301	Inositol Polyphosphate Multikinase Inhibits Angiogenesis via Inositol Pentakisphosphate-Induced HIF-1Î± Degradation.	Circulation Research	2018
29728588	Multiple aspects of male germ cell development and interactions with Sertoli cells require inositol hexakisphosphate kinase-1.	Scientific Reports	2018
29317536	Golgi stress response reprograms cysteine metabolism to confer cytoprotection in Huntington's disease.	Proceedings of the National Academy of Sciences of the United States of America	2018