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Author Details

Gary H Karpen
University of California Berkeley
1981
102
57
PMIDPaper TitleJournal TitlePublished Year
36682829Mouse genomic associations with in vitro sensitivity to simulated space radiation.Life Sci Space Res (Amst)2023
37841837Affinity hierarchies and amphiphilic proteins underlie the co-assembly of nucleolar and heterochromatin condensates.Res Sq2023
37808710Affinity hierarchies and amphiphilic proteins underlie the co-assembly of nucleolar and heterochromatin condensates.bioRxiv2023
37549295HP1-driven phase separation recapitulates the thermodynamics and kinetics of heterochromatin condensate formation.Proc Natl Acad Sci U S A2023
36682829Mouse genomic associations with in vitro sensitivity to simulated space radiation.Life Sci Space Res (Amst)2023
37808710Affinity hierarchies and amphiphilic proteins underlie the co-assembly of nucleolar and heterochromatin condensates.bioRxiv2023
37549295HP1-driven phase separation recapitulates the thermodynamics and kinetics of heterochromatin condensate formation.Proc Natl Acad Sci U S A2023
37841837Affinity hierarchies and amphiphilic proteins underlie the co-assembly of nucleolar and heterochromatin condensates.Res Sq2023
32203508Pericentromeric heterochromatin is hierarchically organized and spatially contacts H3K9me2 islands in euchromatin.PLoS Genet2020
32203508Pericentromeric heterochromatin is hierarchically organized and spatially contacts H3K9me2 islands in euchromatin.PLoS Genet2020
33169670Innovation of heterochromatin functions drives rapid evolution of essential ZAD-ZNF genes in <i>Drosophila</i>.Elife2020
33169670Innovation of heterochromatin functions drives rapid evolution of essential ZAD-ZNF genes in <i>Drosophila</i>.Elife2020
30578303Timely double-strand break repair and pathway choice in pericentromeric heterochromatin depend on the histone demethylase dKDM4A.Genes Dev2019
31687931RNA from a simple-tandem repeat is required for sperm maturation and male fertility in <i>Drosophila melanogaster</i>.Elife2019
30578303Timely double-strand break repair and pathway choice in pericentromeric heterochromatin depend on the histone demethylase dKDM4A.Genes Dev2019
31237235Haplotypes spanning centromeric regions reveal persistence of large blocks of archaic DNA.Elife2019
31687931RNA from a simple-tandem repeat is required for sperm maturation and male fertility in <i>Drosophila melanogaster</i>.Elife2019
31237235Haplotypes spanning centromeric regions reveal persistence of large blocks of archaic DNA.Elife2019
30044650Heterochromatin: Guardian of the Genome.Annu Rev Cell Dev Biol2018
30044650Heterochromatin: Guardian of the Genome.Annu Rev Cell Dev Biol2018
28760857FBW7 Loss Promotes Chromosomal Instability and Tumorigenesis via Cyclin E1/CDK2-Mediated Phosphorylation of CENP-A.Cancer Res2017
28695823Pervasive epigenetic effects of <i>Drosophila</i> euchromatic transposable elements impact their evolution.Elife2017
28636597Phase separation drives heterochromatin domain formation.Nature2017
28760857FBW7 Loss Promotes Chromosomal Instability and Tumorigenesis via Cyclin E1/CDK2-Mediated Phosphorylation of CENP-A.Cancer Res2017
28980868Exploring the role of CENP-A Ser18 phosphorylation in CIN and Tumorigenesis.Cell Cycle2017
28743002Drosophila Histone Demethylase KDM4A Has Enzymatic and Non-enzymatic Roles in Controlling Heterochromatin Integrity.Dev Cell2017
28980868Exploring the role of CENP-A Ser18 phosphorylation in CIN and Tumorigenesis.Cell Cycle2017
28695823Pervasive epigenetic effects of <i>Drosophila</i> euchromatic transposable elements impact their evolution.Elife2017
28743002Drosophila Histone Demethylase KDM4A Has Enzymatic and Non-enzymatic Roles in Controlling Heterochromatin Integrity.Dev Cell2017
28636597Phase separation drives heterochromatin domain formation.Nature2017
27577169Centromere and kinetochore gene misexpression predicts cancer patient survival and response to radiotherapy and chemotherapy.Nat Commun2016
27474442A single double-strand break system reveals repair dynamics and mechanisms in heterochromatin and euchromatin.Genes Dev2016
27577169Centromere and kinetochore gene misexpression predicts cancer patient survival and response to radiotherapy and chemotherapy.Nat Commun2016
27892936Influence of early life exposure, host genetics and diet on the mouse gut microbiome and metabolome.Nat Microbiol2016
27514026The composition and organization of Drosophila heterochromatin are heterogeneous and dynamic.Elife2016
27892936Influence of early life exposure, host genetics and diet on the mouse gut microbiome and metabolome.Nat Microbiol2016
27474442A single double-strand break system reveals repair dynamics and mechanisms in heterochromatin and euchromatin.Genes Dev2016
27514026The composition and organization of Drosophila heterochromatin are heterogeneous and dynamic.Elife2016
25589440The Release 6 reference sequence of the Drosophila melanogaster genome.Genome Res2015
25589440The Release 6 reference sequence of the Drosophila melanogaster genome.Genome Res2015
25747469Identification of genetic loci that control mammary tumor susceptibility through the host microenvironment.Sci Rep2015
26548763Identification of genetic factors that modify motor performance and body weight using Collaborative Cross mice.Sci Rep2015
26502056Heterochromatic breaks move to the nuclear periphery to continue recombinational repair.Nat Cell Biol2015
26502056Heterochromatic breaks move to the nuclear periphery to continue recombinational repair.Nat Cell Biol2015
26548763Identification of genetic factors that modify motor performance and body weight using Collaborative Cross mice.Sci Rep2015
25747469Identification of genetic loci that control mammary tumor susceptibility through the host microenvironment.Sci Rep2015
24598259Impact of sequencing depth in ChIP-seq experiments.Nucleic Acids Res2014
24994117An interferon signature identified by RNA-sequencing of mammary tissues varies across the estrous cycle and is predictive of metastasis-free survival.Oncotarget2014
24991813Nucleosomes shape DNA polymorphism and divergence.PLoS Genet2014
24908378Editorial overview: Cell nucleus: the nucleus: a dynamic organelle.Curr Opin Cell Biol2014
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Collaborators

Lawrence Berkeley National Laboratory
Co-authored papers 10
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Harvard Medical School
Co-authored papers 9
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Dana-Farber Cancer Institute
Co-authored papers 8
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Carnegie Institution for Science/Howard Hughes Medical Institute
Co-authored papers 7
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Duke University School of Medicine
Co-authored papers 6
University of California berkeley
Co-authored papers 6
Lawrence Berkeley National Laboratory
Co-authored papers 6
National Center for Biotechnology Information, National Institutes of Health
Co-authored papers 5
NASA Ames Research Center
Co-authored papers 5
Co-authored papers 5
Massachusetts Institute of Technology
Co-authored papers 5
US Department of Energy Joint Genome Institute, Lawrence Berkeley National Laboratory
Co-authored papers 4
Max Planck Institute of Molecular Cell Biology and Genetics
Co-authored papers 4
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Lawrence Berkeley National Laboratory
Co-authored papers 4
Wellcome Sanger Institute
Co-authored papers 4
The University of Chicago
Co-authored papers 3
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Instituto de Biologia, Universidade Federal do Rio de Janeiro
Co-authored papers 3