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Author Details

Robert Landick
University of Wisconsin-Madison
1980
222
72
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36631609Structural basis for intrinsic transcription termination.Nature2023
37540747Single-cell analysis of multiple invertible promoters reveals differential inversion rates as a strong determinant of bacterial population heterogeneity.Sci Adv2023
38029103Evolutionary flexibility and rigidity in the bacterial methylerythritol phosphate (MEP) pathway.Front Microbiol2023
37116494Structural and functional basis of the universal transcription factor NusG pro-pausing activity in Mycobacterium tuberculosis.Mol Cell2023
36795753An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options.Proc Natl Acad Sci U S A2023
36264101RfaH Counter-Silences Inhibition of Transcript Elongation by H-NS-StpA Nucleoprotein Filaments in Pathogenic Escherichia coli.mBio2022
35669520Bacterial H-NS contacts DNA at the same irregularly spaced sites in both bridged and hemi-sequestered linear filaments.iScience2022
35855392A roadmap for designing narrow-spectrum antibiotics targeting bacterial pathogens.Microb Cell2022
35388215Basis of narrow-spectrum activity of fidaxomicin on Clostridioides difficile.Nature2022
35993778Transcriptomic Data Sets for Zymomonas mobilis 2032 during Fermentation of Ammonia Fiber Expansion (AFEX)-Pretreated Corn Stover and Switchgrass Hydrolysates.Microbiol Resour Announc2022
33417856Bacterial Transcription Continues to Surprise: Activation by Alarmone-Mediated Ï¿-Factor Tethering.Mol Cell2021
33883267Structural basis for backtracking by the SARS-CoV-2 replication-transcription complex.Proc Natl Acad Sci U S A2021
33758867Structural basis for backtracking by the SARS-CoV-2 replication-transcription complex.bioRxiv2021
35146496Seeing gene expression in cells: the future of structural biology.Fac Rev2021
34470825Obligate movements of an active site-linked surface domain control RNA polymerase elongation and pausing via a Phe pocket anchor.Proc Natl Acad Sci U S A2021
34705427Conserved Trigger Loop Histidine of RNA Polymerase II Functions as a Positional Catalyst Primarily through Steric Effects.Biochemistry2021
34592433Crabtree/Warburg-like aerobic xylose fermentation by engineered Saccharomyces cerevisiae.Metab Eng2021
34276640Corrigendum: A Markerless Method for Genome Engineering in <i>Zymomonas mobilis</i> ZM4.Front Microbiol2021
34019789Chemical-genetic interrogation of RNA polymerase mutants reveals structure-function relationships and physiological tradeoffs.Mol Cell2021
34348029Transcriptional Pausing as a Mediator of Bacterial Gene Regulation.Annu Rev Microbiol2021
32694125Genome-Scale Transcription-Translation Mapping Reveals Features of Zymomonas mobilis Transcription Units and Promoters.mSystems2020
31974358Alternative transcription cycle for bacterial RNA polymerase.Nat Commun2020
33199626The antibiotic sorangicin A inhibits promoter DNA unwinding in a <i>Mycobacterium tuberculosis</i> rifampicin-resistant RNA polymerase.Proc Natl Acad Sci U S A2020
33168725A majority of <i>Rhodobacter sphaeroides</i> promoters lack a crucial RNA polymerase recognition feature, enabling coordinated transcription activation.Proc Natl Acad Sci U S A2020
32883797Genome-Wide Identification of Transcription Start Sites in Two <i>Alphaproteobacteria</i>, Rhodobacter sphaeroides 2.4.1 and Novosphingobium aromaticivorans DSM 12444.Microbiol Resour Announc2020
32797046Heterologous expression of a glycosyl hydrolase and cellular reprogramming enable Zymomonas mobilis growth on cellobiose.PLoS One2020
32963084CRISpy-Pop: A Web Tool for Designing CRISPR/Cas9-Driven Genetic Modifications in Diverse Populations.G3 (Bethesda)2020
32590077Regulated redirection of central carbon flux enhances anaerobic production of bioproducts in Zymomonas mobilis.Metab Eng2020
30618376The elemental mechanism of transcriptional pausing.Elife2019
31787963Multiomic Fermentation Using Chemically Defined Synthetic Hydrolyzates Revealed Multiple Effects of Lignocellulose-Derived Inhibitors on Cell Physiology and Xylose Utilization in <i>Zymomonas mobilis</i>.Front Microbiol2019
31681183A Markerless Method for Genome Engineering in <i>Zymomonas mobilis</i> ZM4.Front Microbiol2019
31297978Systems Metabolic Engineering of Escherichia coli Improves Coconversion of Lignocellulose-Derived Sugars.Biotechnol J2019
31310765Mechanisms of Transcriptional Pausing in Bacteria.J Mol Biol2019
31153903Transcription of Bacterial Chromatin.J Mol Biol2019
30720429Delayed inhibition mechanism for secondary channel factor regulation of ribosomal RNA transcription.Elife2019
30633862A Regulatory NADH/NAD+ Redox Biosensor for Bacteria.ACS Synth Biol2019
30630008RNA Polymerase Clamp Movement Aids Dissociation from DNA but Is Not Required for RNA Release at Intrinsic Terminators.J Mol Biol2019
30594629OptSSeq explores enzyme expression and function landscapes to maximize isobutanol production rate.Metab Eng2019
29329531Chemical genomic guided engineering of gamma-valerolactone tolerant yeast.Microb Cell Fact2018
29887376Structural Basis for Transcript Elongation Control by NusG Family Universal Regulators.Cell2018
30045857Natural Variation in the Multidrug Efflux Pump <i>SGE1</i> Underlies Ionic Liquid Tolerance in Yeast.Genetics2018
30122535Mechanism for the Regulated Control of Bacterial Transcription Termination by a Universal Adaptor Protein.Mol Cell2018
30109619In Vitro Transcription Assay to Quantify Effects of H-NS Filaments on RNA Chain Elongation by RNA Polymerase.Methods Mol Biol2018
29499135RNA Polymerase Accommodates a Pause RNA Hairpin by Global Conformational Rearrangements that Prolong Pausing.Mol Cell2018
29743953Complete genome sequence and the expression pattern of plasmids of the model ethanologen <i>Zymomonas mobilis</i> ZM4 and its xylose-utilizing derivatives 8b and 2032.Biotechnol Biofuels2018
29718386StpA and Hha stimulate pausing by RNA polymerase by promoting DNA-DNA bridging of H-NS filaments.Nucleic Acids Res2018
29507289Life times of metastable states guide regulatory signaling in transcriptional riboswitches.Nat Commun2018
29480804Fidaxomicin jams <i>Mycobacterium tuberculosis</i> RNA polymerase motions needed for initiation via RbpA contacts.Elife2018
28546214RNA polymerase motions during promoter melting.Science2017
28137878Dynamics of GreB-RNA polymerase interaction allow a proofreading accessory protein to patrol for transcription complexes needing rescue.Proc Natl Acad Sci U S A2017
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Collaborators

Rachel A Mooney
University of Wisconsin-Madison
Co-authored papers 46
Seth A Darst
The Rockefeller University
Co-authored papers 26
Yaoping Zhang
DOE Great Lakes Bioenergy Research Center, University of Wisconsin-Madison
Co-authored papers 15
Carol A Gross
University of California san francisco
Co-authored papers 8
Audrey P Gasch
University of Wisconsin-Madison
Co-authored papers 7
Jason M Peters
School of Pharmacy, University of Wisconsin-Madison
Co-authored papers 7
Brian T Chait
The Rockefeller University
Co-authored papers 4
Chad L Myers
University of Minnesota - Twin Cities
Co-authored papers 4
Michael Place
Center for Genomic Science Innovation, University of Wisconsin-Madison
Co-authored papers 3
William J Greenleaf
Stanford University
Co-authored papers 3
Timothy J Donohue
University of Wisconsin
Co-authored papers 3
Charles Boone
University of Toronto
Co-authored papers 3
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Columbia University
Co-authored papers 2
Paul Dominic B Olinares
The Rockefeller University
Co-authored papers 2
Bernhard O Palsson
University of California San Diego
Co-authored papers 2
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Memorial Sloan Kettering Cancer Center
Co-authored papers 2
Blake A Simmons
Joint BioEnergy Institute, USA Lawrence Berkeley National Laboratory
Co-authored papers 2
Melvin I Simon
Co-authored papers 1
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 1
Jeremy M Rock
The Rockefeller University
Co-authored papers 1
Peter I Wu
Texas A&M University, College Station
Co-authored papers 1
Nathan E Lewis
University of California San Diego
Co-authored papers 1
Michael A Kohanski
Co-authored papers 1
Mikhail Kashlev
Co-authored papers 1
Sergei Borukhov
Rowan University School of Osteopathic Medicine
Co-authored papers 1
Nicholas D Socci
Co-authored papers 1
Stephen J Elledge
Howard Hughes Medical Institute, Brigham and Women's Hospital, Harvard Medical School
Co-authored papers 1
Hendrik Osadnik
University of California San Francisco
Co-authored papers 1
Steven W Singer
Co-authored papers 1
Carlos Bustamante
University of California berkeley
Co-authored papers 1
Release 1.2