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Author Details

Linda T Hiraki
Research Institute, The Hospital for Sick Children
2002
61
26
PMIDPaper TitleJournal TitlePublished Year
36379578Genome-Wide Sequencing Identified Rare Genetic Variants for Childhood-Onset Monogenic Lupus.J Rheumatol2023
37488248Transmission disequilibrium analysis of whole genome data in childhood-onset systemic lupus erythematosus.Genes Immun2023
37353795A multi-site pilot randomized clinical trial of the Treatment and Education Approach for Childhood-onset Lupus (TEACH) program: study design and COVID-19 adaptations.Pediatr Rheumatol Online J2023
37204055Persistently active interferon-γ pathway and expansion of T-bet<sup>+</sup> B cells in a subset of patients with childhood-onset systemic lupus erythematosus.Eur J Immunol2023
36996277Maternal Anti-Ro Antibody Titers Obtained With Commercially Available Immunoassays Are Strongly Associated With Immune-Mediated Fetal Heart Disease.Arthritis Rheumatol2023
36926348Case report: Novel variants in RELA associated with familial Behcet's-like disease.Front Immunol2023
36651668Genetics of osteonecrosis in children and adults with systemic lupus erythematosus.Rheumatology (Oxford)2023
36916720Genetics of longitudinal kidney function in children and adults with systemic lupus erythematosus.Rheumatology (Oxford)2023
36765391Interferon and interferon-induced cytokines as markers of impending clinical progression in ANA<sup>+</sup> individuals without a systemic autoimmune rheumatic disease diagnosis.Arthritis Res Ther2023
32976694Timing of Childhood-Onset Systemic Lupus Erythematosus Diagnosis Relative to Menarche and the Impact on Final Adult Height.Arthritis Care Res (Hoboken)2022
35844549Altered Balance of Pro-Inflammatory Immune Cells to T Regulatory Cells Differentiates Symptomatic From Asymptomatic Individuals With Anti-Nuclear Antibodies.Front Immunol2022
35587043Jagged Ends on Multinucleosomal Cell-Free DNA Serve as a Biomarker for Nuclease Activity and Systemic Lupus Erythematosus.Clin Chem2022
35649546Hemophagocytic Lymphohistiocytosis Gene Variants in Childhood-Onset Systemic Lupus Erythematosus With Macrophage Activation Syndrome.J Rheumatol2022
36288287Epigenetic analysis of cell-free DNA by fragmentomic profiling.Proc Natl Acad Sci U S A2022
34599046Schizophrenia Genetics and Neuropsychiatric Features in Childhood-onset Systemic Lupus Erythematosus.J Rheumatol2022
34175923Serological abnormalities that predict progression to systemic autoimmune rheumatic diseases in antinuclear antibody-positive individuals.Rheumatology (Oxford)2022
33262295Predicting Macrophage Activation Syndrome in Childhood-onset Systemic Lupus Erythematosus Patients at Diagnosis.J Rheumatol2021
33795326Ethnicity and Neonatal Lupus Erythematosus Manifestations Risk in a Large Multiethnic Cohort.J Rheumatol2021
33592603Effects of Transplacental Dexamethasone Therapy on Fetal Immune-Mediated Complete Heart Block.Fetal Diagn Ther2021
34470801Nuclease deficiencies alter plasma cell-free DNA methylation profiles.Genome Res2021
34078154Evaluation of self-report screening measures in the detection of depressive and anxiety disorders among children and adolescents with systemic lupus erythematosus.Lupus2021
31236574Association of systemic lupus erythematosus (SLE) genetic susceptibility loci with lupus nephritis in childhood-onset and adult-onset SLE.Rheumatology (Oxford)2020
32739899<i>APOL1</i> Gene - Implications for Systemic Lupus Erythematosus.J Rheumatol2020
33022220Plasma DNA Profile Associated with DNASE1L3 Gene Mutations: Clinical Observations, Relationships to Nuclease Substrate Preference, and In Vivo Correction.Am J Hum Genet2020
31131280Developing Reflection and Collaboration in Translational Medicine Toward Patients and Unmet Medical Needs.Front Med (Lausanne)2019
30770510Comparison of Sensitivities of American College of Rheumatology and Systemic Lupus International Collaborating Clinics Classification Criteria in Childhood-onset Systemic Lupus Erythematosus.J Rheumatol2019
28771251Improved diagnostic yield compared with targeted gene sequencing panels suggests a role for whole-genome sequencing as a first-tier genetic test.Genet Med2018
30173152Canadian Rheumatology Association Recommendations for the Assessment and Monitoring of Systemic Lupus Erythematosus.J Rheumatol2018
30504478Genome-wide Sequencing in Rheumatic Diseases.J Rheumatol2018
29703844A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes.Diabetes2018
29342508Features, Treatment, and Outcomes of Macrophage Activation Syndrome in Childhood-Onset Systemic Lupus Erythematosus.Arthritis Rheumatol2018
27647854The Genetic Landscape of Renal Complications in Type 1 Diabetes.J Am Soc Nephrol2017
28217919Serious Infection Rates Among Children With Systemic Lupus Erythematosus Enrolled in Medicaid.Arthritis Care Res (Hoboken)2017
28711143Genomics of Systemic Lupus Erythematosus: Insights Gained by Studying Monogenic Young-Onset Systemic Lupus Erythematosus.Rheum Dis Clin North Am2017
27207532New Locus for Skin Intrinsic Fluorescence in Type 1 Diabetes Also Associated With Blood and Skin Glycated Proteins.Diabetes2016
26631737Genome-wide Association Studies Identify Genetic Loci Associated With Albuminuria in Diabetes.Diabetes2016
24685909Improved performance of epidemiologic and genetic risk models for rheumatoid arthritis serologic phenotypes using family history.Ann Rheum Dis2015
25692470Human papillomavirus vaccine uptake among individuals with systemic inflammatory diseases.PLoS One2015
25772621Serious infections among adult Medicaid beneficiaries with systemic lupus erythematosus and lupus nephritis.Arthritis Rheumatol2015
24394681Chicken or the egg: anorexia nervosa and systemic lupus erythematosus in children and adolescents.Pediatrics2014
25065001Circulating 25-hydroxyvitamin D level and risk of developing rheumatoid arthritis.Rheumatology (Oxford)2014
25057178Being overweight or obese and risk of developing rheumatoid arthritis among women: a prospective cohort study.Ann Rheum Dis2014
25103278Contributions of familial rheumatoid arthritis or lupus and environmental factors to risk of rheumatoid arthritis in women: a prospective cohort study.Arthritis Care Res (Hoboken)2014
24670869Joint effects of colorectal cancer susceptibility loci, circulating 25-hydroxyvitamin D and risk of colorectal cancer.PLoS One2014
23135809Exploring the genetic architecture of circulating 25-hydroxyvitamin D.Genet Epidemiol2013
23983240Genetic predictors of circulating 25-hydroxyvitamin d and risk of colorectal cancer.Cancer Epidemiol Biomarkers Prev2013
23393431Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts.PLoS Med2013
23203603Epidemiology and sociodemographics of systemic lupus erythematosus and lupus nephritis among US adults with Medicaid coverage, 2000-2004.Arthritis Rheum2013
22949264Reply: To PMID 22744978.Arthritis Care Res (Hoboken)2013
22847366Prevalence, incidence, and demographics of systemic lupus erythematosus and lupus nephritis from 2000 to 2004 among children in the US Medicaid beneficiary population.Arthritis Rheum2012
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Collaborators

Karen H Costenbader
Co-authored papers 12
Elizabeth W Karlson
Brigham and Women's Hospital
Co-authored papers 7
Andrew D Paterson
The Hospital for Sick Children
Co-authored papers 7
Zahi Touma
Schroeder Arthritis Institute, Krembil Research Institute, University Health Network
Co-authored papers 7
Joan E Wither
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Co-authored papers 6
Murray B Urowitz
Schroeder Arthritis Institute, Krembil Research Institute, University Health Network
Co-authored papers 4
Peter Kraft
Harvard T. H. Chan School of Public Health
Co-authored papers 4
Dafna D Gladman
Schroeder Arthritis Institute, Krembil Research Institute, Toronto Western Hospital
Co-authored papers 4
Carolina Mu??oz-Grajales
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Co-authored papers 3
Arthur Bookman
University of Toronto
Co-authored papers 3
Mark I McCarthy
Co-authored papers 3
Dennisse Bonilla
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Zareen Ahmad
Mount Sinai Hospital.
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Sindhu R Johnson
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Eric B Fauman
Co-authored papers 2
Jose C Florez
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Claes Ladenvall
Co-authored papers 2
Mary Julia Brosnan
Co-authored papers 2
Nigel W Rayner
Co-authored papers 2
Leif Groop
Co-authored papers 2
Joel N Hirschhorn
Broad Institute of MIT and Harvard
Co-authored papers 2
Christian R Marshall
Co-authored papers 2
Emma Ahlqvist
Co-authored papers 2
Nicholas J Wareham
Co-authored papers 2
Ruth J F Loos
Co-authored papers 2
Andrew T Chan
Massachusetts General Hospital and Harvard Medical School
Co-authored papers 2
Braxton D Mitchell
Co-authored papers 2
Valeriya Lyssenko
Co-authored papers 2
Per-Henrik Groop
Folkhalsan Institute of Genetics, Folkhalsan Research Center
Co-authored papers 2
Luigi Ferrucci
National Institute on Aging, National Institutes of Health
Co-authored papers 2
Release 1.2