Author details

Full Name

Zhidong Tu

Affiliation

ORCID

Career Start Year

2004

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36951513	Multiscale network analysis identifies potential receptors for SARS-CoV-2 and reveals their tissue-specific and age-dependent expression.		2023
37938972	Integration of transcriptomes of senescent cell models with multi-tissue patient samples reveals reduced COL6A3 as an inducer of senescence.	Cell Rep	2023
37284017	Molecular differences in brain regional vulnerability to aging between males and females.	Front Aging Neurosci	2023
35000600	The landscape of human tissue and cell type specific expression and co-regulation of senescence genes.	Mol Neurodegener	2022
34529725	A comprehensive integrated post-GWAS analysis of Type 1 diabetes reveals enhancer-based immune dysregulation.	PLoS One	2021
34018656	Age-related telomere attrition causes aberrant gene expression in sub-telomeric regions.	Aging Cell	2021
33483510	An integrative multiomic network model links lipid metabolism to glucose regulation in coronary artery disease.	Nat Commun	2021
34140970	A Compendium of Age-Related PheWAS and GWAS Traits for Human Genetic Association Studies, Their Networks and Genetic Correlations.	Frontiers in Genetics	2021
34924992	Transcriptomic Changes Highly Similar to Alzheimer's Disease Are Observed in a Subpopulation of Individuals During Normal Brain Aging.	Front Aging Neurosci	2021
32770063	Multiscale causal networks identify VGF as a key regulator of Alzheimer's disease.	Nat Commun	2020
32077223	Transcriptome analysis reveals the difference between "healthy" and "common" aging and their connection with age-related diseases.	Aging Cell	2020
31637571	Human geroprotector discovery by targeting the converging subnetworks of aging and age-related diseases.	Geroscience	2020
33101366	Improved Human Age Prediction by Using Gene Expression Profiles From Multiple Tissues.	Frontiers in Genetics	2020
31289834	A probabilistic multi-omics data matching method for detecting sample errors in integrative analysis.	Gigascience	2019
30266904	Temporal genetic association and temporal genetic causality methods for dissecting complex networks.	Nat Commun	2018
28041957	Human Pancreatic Î² Cell lncRNAs Control Cell-Specific Regulatory Networks.	Cell Metab	2017
29273013	A next generation sequencing based approach to identify extracellular vesicle mediated mRNA transfers between cells.	BMC Genomics	2017
27582315	Discover the network underlying the connections between aging and age-related diseases.	Sci Rep	2016
27251275	Proteogenomics connects somatic mutations to signalling in breast cancer.	Nature	2016
26795431	Corrigendum: Synchronized age-related gene expression changes across multiple tissues in human and the link to complex diseases.	Sci Rep	2016
26733076	New Method for Joint Network Analysis Reveals Common and Different Coexpression Patterns among Genes and Proteins in Breast Cancer.	Journal of Proteome Research	2016
26856537	Inter-tissue coexpression network analysis reveals DPP4 as an important gene in heart to blood communication.	Genome Medicine	2016
26072483	Integrative random forest for gene regulatory network inference.		2015
25765547	A systems genetics study of swine illustrates mechanisms underlying human phenotypic traits.	BMC Genomics	2015
26477495	Synchronized age-related gene expression changes across multiple tissues in human and the link to complex diseases.	Sci Rep	2015
25122495	MODMatcher: multi-omics data matcher for integrative genomic analysis.	PLoS Comput Biol	2014
24481529	Multifaceted roles of miR-1s in repressing the fetal gene program in the heart.	Cell Research	2014
25145359	Baf250a orchestrates an epigenetic pathway to repress the Nkx2.5-directed contractile cardiomyocyte program in the sinoatrial node.	Cell Research	2014
23236292	Integrative analysis of a cross-loci regulation network identifies App as a gene regulating insulin secretion from pancreatic islets.	PLoS Genet	2012
22509135	Stitching together multiple data dimensions reveals interacting metabolomic and transcriptomic networks that modulate cell regulation.	PLoS Biol	2012
21330691	The role of Hepatitis C Virus in the dynamic protein interaction networks of hepatocellular cirrhosis and carcinoma.	International Journal of Computational Biology and Drug Design	2011
21172055	TF-centered downstream gene set enrichment analysis: Inference of causal regulators by integrating TF-DNA interactions and protein post-translational modifications information.	BMC Bioinformatics	2010
19435510	A network-based integrative approach to prioritize reliable hits from multiple genome-wide RNAi screens in Drosophila.	BMC Genomics	2009
19261841	Integrating siRNA and protein-protein interaction data to identify an expanded insulin signaling network.	Genome Res	2009
16769903	Network motif identification in stochastic networks.	Proceedings of the National Academy of Sciences of the United States of America	2006
16873511	An integrative approach for causal gene identification and gene regulatory pathway inference.		2006
16504025	Further understanding human disease genes by comparing with housekeeping genes and other genes.	BMC Genomics	2006
16584317	Diffusion kernel-based logistic regression models for protein function prediction.	OMICS	2006
14751964	Mapping Gene Ontology to proteins based on protein-protein interaction data.	Bioinformatics	2004