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Author Details

Yuzhi Jia
Feinberg School of Medicine, Northwestern University
2000
53
26
PMIDPaper TitleJournal TitlePublished Year
36206490PRL2 phosphatase enhances oncogenic FLT3 signaling via dephosphorylation of the E3 ubiquitin ligase CBL at tyrosine 371.Blood2023
37090580Computational ranking-assisted identification of Plexin-B2 in homotypic and heterotypic clustering of circulating tumor cells in breast cancer metastasis.bioRxiv2023
37150240Unique molecular signatures sustained in circulating monocytes and regulatory T cells in convalescent COVID-19 patients.Clin Immunol2023
37272843Dynamic Glycoprotein Hyposialylation Promotes Chemotherapy Evasion and Metastatic Seeding of Quiescent Circulating Tumor Cell Clusters in Breast Cancer.Cancer Discov2023
37398311Ubiquitin-specific peptidase 22 controls integrin-dependent cancer cell stemness and metastasis.Res Sq2023
35058437Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2.Nat Commun2022
35378753Unique molecular signatures sustained in circulating monocytes and regulatory T cells in Convalescent COVID-19 patients.bioRxiv2022
36193887Machine learning-assisted elucidation of CD81-CD44 interactions in promoting cancer stemness and extracellular vesicle integrity.Elife2022
34067416MARCH8 Suppresses Tumor Metastasis and Mediates Degradation of STAT3 and CD44 in Breast Cancer Cells.Cancers (Basel)2021
33649493Surfactant-assisted one-pot sample preparation for label-free single-cell proteomics.Commun Biol2021
34381029ICAM1 initiates CTC cluster formation and trans-endothelial migration in lung metastasis of breast cancer.Nat Commun2021
33995681EGFR inhibition blocks cancer stem cell clustering and lung metastasis of triple negative breast cancer.Theranostics2021
31969394Extracellular Domains I and II of cell-surface glycoprotein CD44 mediate its <i>trans</i>-homophilic dimerization and tumor cluster aggregation.J Biol Chem2020
29772707PIMT/NCOA6IP Deletion in the Mouse Heart Causes Delayed Cardiomyopathy Attributable to Perturbation in Energy Metabolism.Int J Mol Sci2018
30469494Mouse Cardiac Pde1C Is a Direct Transcriptional Target of Pparα.Int J Mol Sci2018
28642237Mediator 1 Is Atherosclerosis Protective by Regulating Macrophage Polarization.Arterioscler Thromb Vasc Biol2017
27045244[Overexpression of PPARγ induces adipogenic steatosis in mouse primary hepatocytes].Zhejiang Da Xue Xue Bao Yi Xue Ban2016
27690354Correction: Cardiomyocyte-Specific Ablation of Med1 Subunit of the Mediator Complex Causes Lethal Dilated Cardiomyopathy in Mice.PLoS One2016
27548259Cardiomyocyte-Specific Ablation of Med1 Subunit of the Mediator Complex Causes Lethal Dilated Cardiomyopathy in Mice.PLoS One2016
25773177PPARα-Deficient ob/ob Obese Mice Become More Obese and Manifest Severe Hepatic Steatosis Due to Decreased Fatty Acid Oxidation.Am J Pathol2015
25778538Med1 regulates meiotic progression during spermatogenesis in mice.Reproduction2015
24401050Mistargeting of peroxisomal EHHADH and inherited renal Fanconi's syndrome.N Engl J Med2014
24801167Med1 subunit of the mediator complex in nuclear receptor-regulated energy metabolism, liver regeneration, and hepatocarcinogenesis.Gene Expr2014
23943624The Med1 subunit of the mediator complex induces liver cell proliferation and is phosphorylated by AMP kinase.J Biol Chem2013
24358311ERK2-mediated phosphorylation of transcriptional coactivator binding protein PIMT/NCoA6IP at Ser298 augments hepatic gluconeogenesis.PLoS One2013
22009939Sustained activation of PPARα by endogenous ligands increases hepatic fatty acid oxidation and prevents obesity in ob/ob mice.FASEB J2012
22982455Early embryonic lethality of mice with disrupted transcription cofactor PIMT/NCOA6IP/Tgs1 gene.Mech Dev2012
22534643Peroxisomal L-bifunctional enzyme (Ehhadh) is essential for the production of medium-chain dicarboxylic acids.J Lipid Res2012
21480322Transcription coactivator mediator subunit MED1 is required for the development of fatty liver in the mouse.Hepatology2011
22260066[Hyperlipidemia in hepatic MED1 deficient mice in response to fasting].Sheng Wu Gong Cheng Xue Bao2011
21801867Progressive endoplasmic reticulum stress contributes to hepatocarcinogenesis in fatty acyl-CoA oxidase 1-deficient mice.Am J Pathol2011
20007298Transcription coactivator PBP/MED1-deficient hepatocytes are not susceptible to diethylnitrosamine-induced hepatocarcinogenesis in the mouse.Carcinogenesis2010
20814439Coactivators in PPAR-Regulated Gene Expression.PPAR Res2010
20885938PRIC295, a Nuclear Receptor Coactivator, Identified from PPARα-Interacting Cofactor Complex.PPAR Res2010
20195242Reversal of mouse Acyl-CoA oxidase 1 (ACOX1) null phenotype by human ACOX1b isoform [corrected].Lab Invest2010
19630272Conditional ablation of mediator subunit MED1 (MED1/PPARBP) gene in mouse liver attenuates glucocorticoid receptor agonist dexamethasone-induced hepatic steatosis.Gene Expr2009
19852756Peroxisome-proliferator-activated receptor-binding protein (PBP) is essential for the growth of active Notch4-immortalized mammary epithelial cells by activating SOX10 expression.Biochem J2009
17462989Transcriptional regulation of Cidea, mitochondrial cell death-inducing DNA fragmentation factor alpha-like effector A, in mouse liver by peroxisome proliferator-activated receptor alpha and gamma.J Biol Chem2007
17962186Induction of nuclear translocation of constitutive androstane receptor by peroxisome proliferator-activated receptor alpha synthetic ligands in mouse liver.J Biol Chem2007
17605299Transcription coactivator PRIP, the peroxisome proliferator-activated receptor (PPAR)-interacting protein, is redundant for the function of nuclear receptors PParalpha and CAR, the constitutive androstane receptor, in mouse liver.Gene Expr2007
17438330Critical role for transcription coactivator peroxisome proliferator-activated receptor (PPAR)-binding protein/TRAP220 in liver regeneration and PPARalpha ligand-induced liver tumor development.J Biol Chem2007
16828057Peroxisome proliferator-activated receptor (PPAR)-binding protein (PBP) but not PPAR-interacting protein (PRIP) is required for nuclear translocation of constitutive androstane receptor in mouse liver.Biochem Biophys Res Commun2006
15647257Peroxisome proliferator-activated receptor-binding protein null mutation results in defective mammary gland development.J Biol Chem2005
16109766Transcription coactivator peroxisome proliferator-activated receptor-binding protein/mediator 1 deficiency abrogates acetaminophen hepatotoxicity.Proc Natl Acad Sci U S A2005
15150259Transcription coactivator PBP, the peroxisome proliferator-activated receptor (PPAR)-binding protein, is required for PPARalpha-regulated gene expression in liver.J Biol Chem2004
12730364Protein kinase involved in lung injury susceptibility: evidence from enzyme isoform genetic knockout and in vivo inhibitor treatment.Proc Natl Acad Sci U S A2003
14500732Overexpression of peroxisome proliferator-activated receptor-alpha (PPARalpha)-regulated genes in liver in the absence of peroxisome proliferation in mice deficient in both L- and D-forms of enoyl-CoA hydratase/dehydrogenase enzymes of peroxisomal beta-oxidation system.J Biol Chem2003
11939592The neuronal migration defect in mice with Zellweger syndrome (Pex5 knockout) is not caused by the inactivity of peroxisomal beta-oxidation.J Neuropathol Exp Neurol2002
12429965Expression of peroxisome proliferator-activated receptor alpha, and PPARalpha regulated genes in spontaneously developed hepatocellular carcinomas in fatty acyl-CoA oxidase null mice.Int J Oncol2002
11986211Fibronectin- and protein kinase C-mediated activation of ERK/MAPK are essential for proplateletlike formation.Blood2002
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Collaborators

Co-authored papers 13
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Weill Cornell School of Medicine
Co-authored papers 6
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Pacific Northwest National Laboratory
Co-authored papers 4
The Second Affiliated Hospital of Nanchang University
Co-authored papers 4
Pacific Northwest National Laboratory
Co-authored papers 4
Northwestern University Feinberg School of Medicine
Co-authored papers 3
Northwestern University
Co-authored papers 3
Washington University School of Medicine
Co-authored papers 2
Co-authored papers 2
NorthShore University HealthSystem, Research Institute, 1001 University Place
Co-authored papers 2
Pacific Northwest National Laboratory
Co-authored papers 2
Co-authored papers 2
Co-authored papers 2
Oregon Health and Science University
Co-authored papers 1
Ferring Research Institute Inc
Co-authored papers 1
Johns Hopkins University School of Medicine
Co-authored papers 1
Co-authored papers 1
Institute of Functional Genomics, University of Regensburg
Co-authored papers 1
Pacific Northwest National Laboratory
Co-authored papers 1
USA Knoxville College of Nursing, University of Tennessee (L.C.K.)
Co-authored papers 1
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Pacific Northwest National Laboratory
Co-authored papers 1
Great Ormond Street Hospital for Children, NHS Foundation Trust
Co-authored papers 1
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University of Kentucky
Co-authored papers 1
Seattle Children's Hospital, University of Washington
Co-authored papers 1
National Medical Research Center of Cardiology Named after Academician E.I. Chazov
Co-authored papers 1