|
| 36701411 | Heterozygous deletion of Gpr55 does not affect a hyperthermia-induced seizure, spontaneous seizures or survival in the Scn1a+/- mouse model of Dravet syndrome. | PLoS One | 2023 |
| 37034689 | Altered neurological and neurobehavioral phenotypes in a mouse model of the recurrent <i>KCNB1</i>-p.R306C voltage-sensor variant. | bioRxiv | 2023 |
| 37333275 | Strain-dependent effects on neurobehavioral and seizure phenotypes in <i>Scn2a<sup>K1422E</sup></i> mice. | bioRxiv | 2023 |
| 37163100 | Evaluating the interplay between estrous cyclicity and induced seizure susceptibility in <i>Scn2a</i><sup><i>K1422E</i></sup> mice. | bioRxiv | 2023 |
| 36808153 | Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub. | Nat Commun | 2023 |
| 35417922 | Cellular and behavioral effects of altered NaV1.2 sodium channel ion permeability in Scn2aK1422E mice. | Hum Mol Genet | 2022 |
| 35346832 | K<sub>Na</sub>1.1 gain-of-function preferentially dampens excitability of murine parvalbumin-positive interneurons. | Neurobiol Dis | 2022 |
| 35606653 | Fine mapping and candidate gene analysis of a dravet syndrome modifier locus on mouse chromosome 11. | Mamm Genome | 2022 |
| 35435735 | Cell-Selective Adeno-Associated Virus-Mediated <i>SCN1A</i> Gene Regulation Therapy Rescues Mortality and Seizure Phenotypes in a Dravet Syndrome Mouse Model and Is Well Tolerated in Nonhuman Primates. | Hum Gene Ther | 2022 |
| 33132203 | Epilepsy and neurobehavioral abnormalities in mice with a dominant-negative KCNB1 pathogenic variant. | Neurobiol Dis | 2021 |
| 34384142 | Cannabigerolic acid, a major biosynthetic precursor molecule in cannabis, exhibits divergent effects on seizures in mouse models of epilepsy. | Br J Pharmacol | 2021 |
| 34510432 | Soticlestat, a novel cholesterol 24-hydroxylase inhibitor, reduces seizures and premature death in Dravet syndrome mice. | Epilepsia | 2021 |
| 34079465 | The Heat Sensing Trpv1 Receptor Is Not a Viable Anticonvulsant Drug Target in the <i>Scn1a</i> <sup><i>+/-</i></sup> Mouse Model of Dravet Syndrome. | Front Pharmacol | 2021 |
| 34045209 | Enhanced Synaptic Transmission in the Extended Amygdala and Altered Excitability in an Extended Amygdala to Brainstem Circuit in a Dravet Syndrome Mouse Model. | eNeuro | 2021 |
| 34086081 | Gabra2 is a genetic modifier of Dravet syndrome in mice. | Mamm Genome | 2021 |
| 32515017 | SCN3A-Related Neurodevelopmental Disorder: A Spectrum of Epilepsy and Brain Malformation. | Ann Neurol | 2020 |
| 31973592 | Epilepsy Benchmarks Area IV: Limit or Prevent Adverse Consequence of Seizures and Their Treatment Across the Life Span. | Epilepsy Curr | 2020 |
| 30347190 | Gene expression profiling in a mouse model of Dravet syndrome. | Exp Neurol | 2019 |
| 31600826 | Spectrum of K<sub>V</sub> 2.1 Dysfunction in KCNB1-Associated Neurodevelopmental Disorders. | Ann Neurol | 2019 |
| 31045243 | Potentiating α<sub>2</sub> subunit containing perisomatic GABA<sub>A</sub> receptors protects against seizures in a mouse model of Dravet syndrome. | J Physiol | 2019 |
| 29487082 | Peripherally derived T regulatory and γδ T cells have opposing roles in the pathogenesis of intractable pediatric epilepsy. | J Exp Med | 2018 |
| 30104343 | A Transient Developmental Window of Fast-Spiking Interneuron Dysfunction in a Mouse Model of Dravet Syndrome. | J Neurosci | 2018 |
| 29844769 | Expanding the Zebrafish Toolkit for Epilepsy Research. | Epilepsy Curr | 2018 |
| 30868126 | C57BL/6J and C57BL/6N substrains differentially influence phenotype severity in the <i>Scn1a</i> <sup>+/-</sup> mouse model of Dravet syndrome. | Epilepsia Open | 2018 |
| 29782051 | The novel sodium channel modulator GS-458967 (GS967) is an effective treatment in a mouse model of SCN8A encephalopathy. | Epilepsia | 2018 |
| 29671845 | Alphabet Soup: Recurrent De Novo Mutations in Novel Genes Causing Developmental and Epileptic Encephalopathies. | Epilepsy Curr | 2018 |
| 28556246 | Cacna1g is a genetic modifier of epilepsy in a mouse model of Dravet syndrome. | Epilepsia | 2017 |
| 28137877 | CaMKII modulates sodium current in neurons from epileptic <i>Scn2a</i> mutant mice. | Proc Natl Acad Sci U S A | 2017 |
| 28331474 | Sodium Channel β Subunits in Epilepsy: Location, Location, Location. | Epilepsy Curr | 2017 |
| 28235671 | SCN3A deficiency associated with increased seizure susceptibility. | Neurobiol Dis | 2017 |
| 28491900 | Screening of conventional anticonvulsants in a genetic mouse model of epilepsy. | Ann Clin Transl Neurol | 2017 |
| 28491004 | Precision Medicine: NMDA Receptor-Targeted Therapy for <i>GRIN2D</i> Encephalopathy. | Epilepsy Curr | 2017 |
| 28490751 | Unexpected Efficacy of a Novel Sodium Channel Modulator in Dravet Syndrome. | Sci Rep | 2017 |
| 29127345 | The synthetic neuroactive steroid SGE-516 reduces seizure burden and improves survival in a Dravet syndrome mouse model. | Sci Rep | 2017 |
| 29225529 | The Big Picture: Systems Biology Approach to Antiepileptic Drug Discovery. | Epilepsy Curr | 2017 |
| 29217985 | A Look Behind the Curtain: Epilepsy Microarray Consortium. | Epilepsy Curr | 2017 |
| 29264390 | Characterization of a <i>KCNB1</i> variant associated with autism, intellectual disability, and epilepsy. | Neurol Genet | 2017 |
| 27073348 | When Inhibiting Repetitive Firing is Pro-Epileptic. | Epilepsy Curr | 2016 |
| 26656780 | Hlf is a genetic modifier of epilepsy caused by voltage-gated sodium channel mutations. | Epilepsy Res | 2016 |
| 27768696 | Fine Mapping of a Dravet Syndrome Modifier Locus on Mouse Chromosome 5 and Candidate Gene Analysis by RNA-Seq. | PLoS Genet | 2016 |
| 27857623 | Cannabidiol Mellows Out Resurgent Sodium Current. | Epilepsy Curr | 2016 |
| 26900380 | Locus Heterogeneity in Epilepsy of Infancy with Migrating Focal Seizures. | Epilepsy Curr | 2016 |
| 27112236 | Cacna1g is a genetic modifier of epilepsy caused by mutation of voltage-gated sodium channel Scn2a. | Epilepsia | 2016 |
| 25678892 | Double trouble: impairment of two interneuron types in a dravet mouse model. | Epilepsy Curr | 2015 |
| 26633958 | Watch Out, No Brakes! Impaired Inhibition Results in Hyperexcitable Networks. | Epilepsy Curr | 2015 |
| 26251648 | TALE of an SCN8A-Associated Epileptic Encephalopathy Mouse Model. | Epilepsy Curr | 2015 |
| 26316853 | Synaptopathies Heat Up: Mutations in STX1B in Fever-Associated Epilepsies. | Epilepsy Curr | 2015 |
| 26933568 | KCNA2-Related Epileptic Encephalopathy. | Pediatr Neurol Briefs | 2015 |
| 24152123 | Mapping genetic modifiers of survival in a mouse model of Dravet syndrome. | Genes Brain Behav | 2014 |
| 25170321 | Epi4K Phase I: Gene Discovery in Epileptic Encephalopathies by Exome Sequencing. | Epilepsy Curr | 2014 |