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Author Details

Teresa P DiLorenzo
Universidad Cardenal Herrera-CEU, CEU Universities
1989
78
35
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36778569A SARS-CoV-2 full genome sequence of the B.1.1 lineage sheds light on viral evolution in Sicily in late 2020.Front Public Health2023
34847567An autoimmune stem-like CD8 T cell population drives type 1 diabetes.Nature2022
36224622Detection of SARS-CoV-2 in a dog with hemorrhagic diarrhea.BMC Vet Res2022
34044020Noncontiguous T cell epitopes in autoimmune diabetes: From mice to men and back again.J Biol Chem2021
34529725A comprehensive integrated post-GWAS analysis of Type 1 diabetes reveals enhancer-based immune dysregulation.PLoS One2021
32561620T-Cell Epitopes and Neo-epitopes in Type 1 Diabetes: A Comprehensive Update and Reappraisal.Diabetes2020
31010879The Evolving Landscape of Autoantigen Discovery and Characterization in Type 1 Diabetes.Diabetes2019
31356169Development and Characterization of a Preclinical Model for the Evaluation of CD205-Mediated Antigen Delivery Therapeutics in Type 1 Diabetes.Immunohorizons2019
29632144HLA-B*39:06 Efficiently Mediates Type 1 Diabetes in a Mouse Model Incorporating Reduced Thymic Insulin Expression.J Immunol2018
29472249Improved Murine MHC-Deficient HLA Transgenic NOD Mouse Models for Type 1 Diabetes Therapy Development.Diabetes2018
26754738Characterization of the peptide binding specificity of the HLA class I alleles B*38:01 and B*39:06.Immunogenetics2016
26412590Delivery of siRNAs to Dendritic Cells Using DEC205-Targeted Lipid Nanoparticles to Inhibit Immune Responses.Mol Ther2016
27124592Genetically modified human CD4(+) T cells can be evaluated in vivo without lethal graft-versus-host disease.Immunology2016
27150089Bridging Mice to Men: Using HLA Transgenic Mice to Enhance the Future Prediction and Prevention of Autoimmune Type 1 Diabetes in Humans.Methods Mol Biol2016
26824049An HLA-Transgenic Mouse Model of Type 1 Diabetes That Incorporates the Reduced but Not Abolished Thymic Insulin Expression Seen in Patients.J Diabetes Res2016
25302633Generation of β cell-specific human cytotoxic T cells by lentiviral transduction and their survival in immunodeficient human leucocyte antigen-transgenic mice.Clin Exp Immunol2015
25333865Glucagon-reactive islet-infiltrating CD8 T cells in NOD mice.Immunology2015
25063871Compensatory mechanisms allow undersized anchor-deficient class I MHC ligands to mediate pathogenic autoreactive T cell responses.J Immunol2014
24021877DEC-205-mediated antigen targeting to steady-state dendritic cells induces deletion of diabetogenic CD8⁺ T cells independently of PD-1 and PD-L1.Int Immunol2013
22539795Beyond HLA-A*0201: new HLA-transgenic nonobese diabetic mouse models of type 1 diabetes identify the insulin C-peptide as a rich source of CD8+ T cell epitopes.J Immunol2012
21825122Structural and functional characterization of a single-chain peptide-MHC molecule that modulates both naive and activated CD8+ T cells.Proc Natl Acad Sci U S A2011
22069259Multiple antigens versus single major antigen in type 1 diabetes: arguing for multiple antigens.Diabetes Metab Res Rev2011
20093428Predominant occupation of the class I MHC molecule H-2Kwm7 with a single self-peptide suggests a mechanism for its diabetes-protective effect.Int Immunol2010
21039471T-cell autoantigens in the non-obese diabetic mouse model of autoimmune diabetes.Immunology2010
20979558An update on the use of NOD mice to study autoimmune (Type 1) diabetes.Expert Rev Clin Immunol2010
20491789The immunotherapeutic potential of dendritic cells in type 1 diabetes.Clin Exp Immunol2010
20404836Autoimmunity. The benefit of self-control.Immunol Cell Biol2010
19966211Ins2 deficiency augments spontaneous HLA-A*0201-restricted T cell responses to insulin.J Immunol2010
20012396Bridging mice to men: using HLA transgenic mice to enhance the future prediction and prevention of autoimmune type 1 diabetes in humans.Methods Mol Biol2010
19112449Lentivectors encoding immunosuppressive proteins genetically engineer pancreatic beta-cells to correct diabetes in allogeneic mice.Gene Ther2009
18184707Lentiviral vectors encoding human immunodeficiency virus type 1 (HIV-1)-specific T-cell receptor genes efficiently convert peripheral blood CD8 T lymphocytes into cytotoxic T lymphocytes with potent in vitro and in vivo HIV-1-specific inhibitory activity.J Virol2008
19120273HLA class I supertypes in type 1 diabetic children in an urban children's hospital.Ann N Y Acad Sci2008
18782577Efficient culture of CD8(+) T cells from the islets of NOD mice and their use for the study of autoreactive specificities.J Immunol Methods2008
18439618Rapid identification of MHC class I-restricted antigens relevant to autoimmune diabetes using retrogenic T cells.J Immunol Methods2008
18430797Selective delivery of beta cell antigen to dendritic cells in vivo leads to deletion and tolerance of autoreactive CD8+ T cells in NOD mice.Proc Natl Acad Sci U S A2008
18358785Identification of novel IGRP epitopes targeted in type 1 diabetes patients.Clin Immunol2008
17237389Improved outcomes in NOD mice treated with a novel Th2 cytokine-biasing NKT cell activator.J Immunol2007
18040044Assembly and structural properties of glucocorticoid-induced TNF receptor ligand: Implications for function.Proc Natl Acad Sci U S A2007
18058037Structural genomics of protein phosphatases.J Struct Funct Genomics2007
17620420In vivo cytotoxicity of insulin-specific CD8+ T-cells in HLA-A*0201 transgenic NOD mice.Diabetes2007
17349009Translational mini-review series on type 1 diabetes: Systematic analysis of T cell epitopes in autoimmune diabetes.Clin Exp Immunol2007
17376821"Humanized" HLA transgenic NOD mice to identify pancreatic beta cell autoantigens of potential clinical relevance to type 1 diabetes.Ann N Y Acad Sci2007
17363302T cell immunoglobulin mucin-3 crystal structure reveals a galectin-9-independent ligand-binding surface.Immunity2007
16229893Structural analysis of H2-Db class I molecules containing two different allelic forms of the type 1 diabetes susceptibility factor beta-2 microglobulin: implications for the mechanism underlying variations in antigen presentation.Mol Immunol2006
16493087HLA-A*0201-restricted T cells from humanized NOD mice recognize autoantigens of potential clinical relevance to type 1 diabetes.J Immunol2006
15790363The good turned ugly: immunopathogenic basis for diabetogenic CD8+ T cells in NOD mice.Immunol Rev2005
15937548Developmental control of CD8 T cell-avidity maturation in autoimmune diabetes.J Clin Invest2005
14707058MHC class II molecules play a role in the selection of autoreactive class I-restricted CD8 T cells that are essential contributors to type 1 diabetes development in nonobese diabetic mice.J Immunol2004
15557165Individual nonobese diabetic mice exhibit unique patterns of CD8+ T cell reactivity to three islet antigens, including the newly identified widely expressed dystrophia myotonica kinase.J Immunol2004
15294969Requirement for both H-2Db and H-2Kd for the induction of diabetes by the promiscuous CD8+ T cell clonotype AI4.J Immunol2004
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Co-authored papers 5
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Co-authored papers 3
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Co-authored papers 3
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Ragon Institute of MGH
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The State University of New Jersey
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Zhidong Tu
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Paul Zumbo
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Release 1.2