Author details

Full Name

Jussi Taipale

Affiliation

ORCID

Career Start Year

2000

Papers

112

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37398193	DNA-guided transcription factor cooperativity shapes face and limb mesenchyme.		2023
36163549	A competitive precision CRISPR method to identify the fitness effects of transcription factor binding sites.	Nature Biotechnology	2023
37740118	Pioneer factors - key regulators of chromatin and gene expression.	Nat Rev Genet	2023
38093018	Hold out the genome: a roadmap to solving the cis-regulatory code.		2023
35190730	Sequence determinants of human gene regulatory elements.	Nat Genet	2022
35472319	Upregulation of ribosome biogenesis via canonical E-boxes is required for Myc-driven proliferation.	Dev Cell	2022
36778047	Type 1 diabetes risk genes mediate pancreatic beta cell survival in response to proinflammatory cytokines.	Cell Genom	2022
34364091	Structural insights into the interaction between transcription factors and the nucleosome.	Current Opinion in Structural Biology	2021
33479524	Author Correction: CRISPR-assisted detection of RNA-protein interactions in living cells.	Nature Methods	2021
34274970	WNT2 activation through proximal germline deletion predisposes to small intestinal neuroendocrine tumors and intestinal adenocarcinomas.	Human Molecular Genetics	2021
33930428	Genetic and Epigenetic Characteristics of Inflammatory Bowel Disease-Associated Colorectal Cancer.	Gastroenterology	2021
33505025	Systematic analysis of binding of transcription factors to noncoding variants.	Nature	2021
33502116	Transcriptionally active enhancers in human cancer cells.	Molecular Systems Biology	2021
34349258	Deficient H2A.Z deposition is associated with genesis of uterine leiomyoma.	Nature	2021
34302118	Human cell transformation by combined lineage conversion and oncogene expression.	Oncogene	2021
33257861	A comprehensive library of human transcription factors for cell fate engineering.	Nat Biotechnol	2021
34521855	Parity associates with chromosomal damage in uterine leiomyomas.	Nature Communications	2021
34572796	Promoter Hypermethylation Promotes the Binding of Transcription Factor NFATc1, Triggering Oncogenic Gene Activation in Pancreatic Cancer.	Cancers	2021
34898428	Rapid genome editing by CRISPR-Cas9-POLD3 fusion.	Elife	2021
32572232	CRISPR-assisted detection of RNA-protein interactions in living cells.	Nature Methods	2020
31846072	The transcription factor FLI1 promotes cancer progression by affecting cell cycle regulation.	International Journal of Cancer	2020
32350470	Nucleosome-bound SOX2 and SOX11 structures elucidate pioneer factor function.	Nature	2020
31999322	MODER2: first-order Markov modeling and discovery of monomeric and dimeric binding motifs.		2020
30890702	Impact of constitutional TET2 haploinsufficiency on molecular and clinical phenotype in humans.	Nature Communications	2019
31464368	Reply to "CRISPR screens are feasible in TP53 wild-type cells".	Molecular Systems Biology	2019
31201888	Gain-of-function CEBPE mutation causes noncanonical autoinflammatory inflammasomopathy.	J Allergy Clin Immunol	2019
29786094	A protein activity assay to measure global transcription factor activity reveals determinants of chromatin accessibility.	Nat Biotechnol	2018
29892067	CRISPR-Cas9 genome editing induces a p53-mediated DNA damage response.	Nature Medicine	2018
30361360	The chromatin of cancer.	Science	2018
30224643	Promoter capture Hi-C-based identification of recurrent noncoding mutations in colorectal cancer.	Nature Genetics	2018
30108113	Comprehensive evaluation of coding region point mutations in microsatellite-unstable colorectal cancer.	EMBO Mol Med	2018
30250250	The interaction landscape between transcription factors and the nucleosome.	Nature	2018
30202008	Contribution of allelic imbalance to colorectal cancer.	Nat Commun	2018
30290144	The Human Transcription Factors.	Cell	2018
29669861	Informational limits of biological organisms.	EMBO Journal	2018
29385521	Modular discovery of monomeric and dimeric transcription factor binding motifs for large data sets.	Nucleic Acids Research	2018
29425488	The Human Transcription Factors.	Cell	2018
29638214	Two distinct DNA sequences recognized by transcription factors represent enthalpy and entropy optima.	eLife	2018
28115215	Damaging heterozygous mutations in NFKB1 lead to diverse immunologic phenotypes.	J Allergy Clin Immunol	2017
28349863	Structural perspective of cooperative transcription factor binding.	Current Opinion in Structural Biology	2017
28993443	CRISPR/Cas9 screening using unique molecular identifiers.	Molecular Systems Biology	2017
28379941	Myt1l safeguards neuronal identity by actively repressing many non-neuronal fates.	Nature	2017
28583252	Mice deficient of <i>Myc</i> super-enhancer region reveal differential control mechanism between normal and pathological growth.	Elife	2017
28611049	Comprehensive Evaluation of Protein Coding Mononucleotide Microsatellites in Microsatellite-Unstable Colorectal Cancer.	Cancer Research	2017
28473536	Impact of cytosine methylation on DNA binding specificities of human transcription factors.	Science	2017
28011774	Fast motif matching revisited: high-order PWMs, SNPs and indels.		2017
27929715	Genome-wide screen of cell-cycle regulators in normal and tumor cells identifies a differential response to nucleosome depletion.	Cell Cycle	2017
28195176	The non-coding variant rs1800734 enhances DCLK3 expression through long-range interaction and promotes colorectal cancer progression.	Nat Commun	2017
28054750	Somatic MED12 Nonsense Mutation Escapes mRNA Decay and Reveals a Motif Required for Nuclear Entry.	Human Mutation	2017
28167566	Transcription factor family-specific DNA shape readout revealed by quantitative specificity models.	Mol Syst Biol	2017