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Author Details

Brady Bernard
2005
32
17
PMIDPaper TitleJournal TitlePublished Year
37202426Extraordinary clinical response to ibrutinib in low-grade ovarian cancer guided by organoid drug testing.2023
36344483Uterine Inflammatory Myofibroblastic Tumors: Proposed Risk Stratification Model Using Integrated Clinicopathologic and Molecular Analysis.American Journal of Surgical Pathology2023
37344474A phase Ib trial of pembrolizumab plus paclitaxel or flat-dose capecitabine in 1st/2nd line metastatic triple-negative breast cancer.2023
35086949Changes in T-cell subsets and clonal repertoire during chemoimmunotherapy with pembrolizumab and paclitaxel or capecitabine for metastatic triple-negative breast cancer.Journal for ImmunoTherapy of Cancer2022
35439168PD-1 and ICOS coexpression identifies tumor-reactive CD4+ T cells in human solid tumors.Journal of Clinical Investigation2022
35413272Transcriptomic profiles of neoantigen-reactive T cells in human gastrointestinal cancers.Cancer Cell2022
33413574Multiplex immunofluorescence to measure dynamic changes in tumor-infiltrating lymphocytes and PD-L1 in early-stage breast cancer.Breast Cancer Research2021
34168978A Case Series of Metastatic Metaplastic Breast Carcinoma Treated With Anti-PD-1 Therapy.Frontiers in Oncology2021
33796412Germinal center reactions in tertiary lymphoid structures associate with neoantigen burden, humoral immunity and long-term survivorship in pancreatic cancer.Oncoimmunology2021
33837055Enhancing clinical and immunological effects of anti-PD-1 with belapectin, a galectin-3 inhibitor.Journal for ImmunoTherapy of Cancer2021
33820811Robust Antitumor Immunity in a Patient with Metastatic Colorectal Cancer Treated with Cytotoxic Regimens.Cancer Immunology Research2021
33596250Developing an enhanced 7-color multiplex IHC protocol to dissect immune infiltration in human cancers.PLoS ONE2021
33594075Neoadjuvant anti-OX40 (MEDI6469) therapy in patients with head and neck squamous cell carcinoma activates and expands antigen-specific tumor-infiltrating T cells.Nature Communications2021
32866185Transcriptional and immunohistological assessment of immune infiltration in pancreatic cancer.PLoS One2020
30833390Genomic and molecular characterization of preterm birth.Proc Natl Acad Sci U S A2019
29596783Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas.Cell Syst2018
28170390Multiscale mutation clustering algorithm identifies pan-cancer mutational clusters associated with pathway-level changes in gene expression.PLoS Comput Biol2017
28331002Personalized In Vitro and In Vivo Cancer Models to Guide Precision Medicine.Cancer Discov2017
27587659Combining dependent P-values with an empirical adaptation of Brown's method.Bioinformatics2016
27426982Causal Mechanistic Regulatory Network for Glioblastoma Deciphered Using Systems Genetics Network Analysis.Cell Syst2016
27047537Using Incomplete Trios to Boost Confidence in Family Based Association Studies.Front Genet2016
26061751Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas.N Engl J Med2015
25737557Genomically amplified Akt3 activates DNA repair pathway and promotes glioma progression.Proc Natl Acad Sci U S A2015
26679347CloudForest: A Scalable and Efficient Random Forest Implementation for Biological Data.PLoS One2015
24794443CTCF haploinsufficiency destabilizes DNA methylation and predisposes to cancer.Cell Rep2014
25378323Structure-based predictions broadly link transcription factor mutations to gene expression changes in cancers.Nucleic Acids Res2014
24591535Synthetic lethal screens as a means to understand and treat MYC-driven cancers.Cold Spring Harb Perspect Med2014
24120142The somatic genomic landscape of glioblastoma.Cell2013
22952610Increasing coverage of transcription factor position weight matrices through domain-level homology.PLoS One2012
19127590A generalized knowledge-based discriminatory function for biomolecular interactions.Proteins2009
18161991Conformational changes below the Tm: molecular dynamics studies of the thermal pretransition of ribonuclease A.Biochemistry2008
16157882Characterization of a possible amyloidogenic precursor in glutamine-repeat neurodegenerative diseases.Proceedings of the National Academy of Sciences of the United States of America2005
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Broad Institute of the Massachusetts Institute of Technology and Harvard
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Earle A. Chiles Research Institute, Providence Cancer Institute
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Broad Institute of MIT and Harvard
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Yale School of Medicine
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Ontario Brain Institute
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Heersink School of Medicine, University of Alabama at Birmingham
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