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Author Details

Jon D Larson
NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute
2000
25
18
Prashant Mali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36264168N-myc-Mediated Translation Control Is a Therapeutic Vulnerability in Medulloblastoma.Cancer Res2023
34890975Integrated genome and tissue engineering enables screening of cancer vulnerabilities in physiologically relevant perfusable ex vivo cultures.Biomaterials2022
31566663ChIPseqSpikeInFree: a ChIP-seq normalization approach to reveal global changes in histone modifications without spike-in.Bioinformatics2020
30595505Histone H3.3 K27M Accelerates Spontaneous Brainstem Glioma and Drives Restricted Changes in Bivalent Gene Expression.Cancer Cell2019
30770999H3.3 K27M depletion increases differentiation and extends latency of diffuse intrinsic pontine glioma growth in vivo.Acta Neuropathol2019
30976974Correction to: H3.3 K27M depletion increases differentiation and extends latency of diffuse intrinsic pontine glioma growth in vivo.Acta Neuropathol2019
30324526Engineering Inducible Knock-In Mice to Model Oncogenic Brain Tumor Mutations from Endogenous Loci.Methods Mol Biol2019
30674530<i>Sleeping Beauty</i> Insertional Mutagenesis Reveals Important Genetic Drivers of Central Nervous System Embryonal Tumors.Cancer Res2019
27815386PTEN Signaling in the Postnatal Perivascular Progenitor Niche Drives Medulloblastoma Formation.Cancer Res2017
26500062Sleeping Beauty transposon screen identifies signaling modules that cooperate with STAT5 activation to induce B-cell acute lymphoblastic leukemia.Oncogene2016
22274699The lineage-specific gene ponzr1 is essential for zebrafish pronephric and pharyngeal arch development.Development2012
22773561Review: In vivo models for defining molecular subtypes of the primitive neuroectodermal tumor genome: current challenges and solutions.In Vivo2012
20388773Sleeping beauty-mediated somatic mutagenesis implicates CSF1 in the formation of high-grade astrocytomas.Cancer Res2010
20736288Moesin1 and Ve-cadherin are required in endothelial cells during in vivo tubulogenesis.Development2010
20206635Heparan sulfate Ndst1 regulates vascular smooth muscle cell proliferation, vessel size and vascular remodeling.J Mol Cell Cardiol2010
19147555De novo induction of genetically engineered brain tumors in mice using plasmid DNA.Cancer Res2009
19389629Combination of reverse and chemical genetic screens reveals angiogenesis inhibitors and targets.Chem Biol2009
17530925p53 activation by knockdown technologies.PLoS Genet2007
16469878Functional analysis of zebrafish microfibril-associated glycoprotein-1 (Magp1) in vivo reveals roles for microfibrils in vascular development and function.Blood2006
17218990Genome-wide reverse genetics framework to identify novel functions of the vertebrate secretome.PLoS One2006
15305301Expression of VE-cadherin in zebrafish embryos: a new tool to evaluate vascular development.Dev Dyn2004
14499652Zebrafish chaperone protein GP96 is required for otolith formation during ear development.Dev Biol2003
15239891Morpholino phosphorodiamidate oligonucleotides in zebrafish: a recipe for functional genomics?Brief Funct Genomic Proteomic2002
11477681Morphant technology in model developmental systems.Genesis2001
11119306Distinct requirements for zebrafish angiogenesis revealed by a VEGF-A morphant.Yeast2000
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