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Author Details

Wayne A Hendrickson
Columbia University
1968
254
89
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36939292Metal-Mediated DNA Nanotechnology in 3D: Structural Library by Templated Diffraction.Adv Mater2023
37530628Heterobimetallic Base Pair Programming in Designer 3D DNA Crystals.J Am Chem Soc2023
37268326Metal-Mediated DNA Nanotechnology in 3D: Structural Library by Templated Diffraction.Adv Mater2023
36961924Indoline CD4-mimetic compounds mediate potent and broad HIV-1 inhibition and sensitization to antibody-dependent cellular cytotoxicity.Proc Natl Acad Sci U S A2023
36574673Crystal structure of LGR ligand α2/β5 from <i>Caenorhabditis elegans</i> with implications for the evolution of glycoprotein hormones.Proc Natl Acad Sci U S A2023
34910339High-throughput cell-free screening of eukaryotic membrane protein expression in lipidic mimetics.Protein Sci2022
35789156Structures and gating mechanisms of human bestrophin anion channels.Nat Commun2022
36655122Structural and Functional Characterization of Indane-Core CD4-Mimetic Compounds Substituted with Heterocyclic Amines.ACS Med Chem Lett2022
36381147Multi-crystal native-SAD phasing at 5 keV with a helium environment.IUCrJ2022
34022208Fine Sampling of Sequence Space for Membrane Protein Structural Biology.J Mol Biol2021
33926963Structure and activity of SLAC1 channels for stomatal signaling in leaves.Proc Natl Acad Sci U S A2021
34916296Symmetric activation and modulation of the human calcium-sensing receptor.Proc Natl Acad Sci U S A2021
34453889Conformational equilibria in allosteric control of Hsp70 chaperones.Mol Cell2021
34795873Identification of gp120 Residue His105 as a Novel Target for HIV-1 Neutralization by Small-Molecule CD4-Mimics.ACS Med Chem Lett2021
33950017Intermediates in allosteric equilibria of DnaK-ATP interactions with substrate peptides.Acta Crystallogr D Struct Biol2021
34166608Gating movements and ion permeation in HCN4 pacemaker channels.Mol Cell2021
32251414Structural and functional characterization of the bestrophin-2 anion channel.Nat Struct Mol Biol2020
33738455Theory of Allosteric Regulation in Hsp70 Molecular Chaperones.QRB Discov2020
32047415PyMDA: microcrystal data assembly using Python.J Appl Crystallogr2020
32679039Structure of the Regulatory Cytosolic Domain of a Eukaryotic Potassium-Chloride Cotransporter.Structure2020
32665714Author Correction: Structure of human GABA<sub>B</sub> receptor in an inactive state.Nature2020
32581365Structure of human GABA<sub>B</sub> receptor in an inactive state.Nature2020
30770441Structural basis for activity of TRIC counter-ion channels in calcium release.Proc Natl Acad Sci U S A2019
31316798Synchrotron microcrystal native-SAD phasing at a low energy.IUCrJ2019
29432144Single-channel recordings of RyR1 at microsecond resolution in CMOS-suspended membranes.Proc Natl Acad Sci U S A2018
30509977Structure and activity of lipid bilayer within a membrane-protein transporter.Proc Natl Acad Sci U S A2018
29755741Sample manipulation and data assembly for robust microcrystal synchrotron crystallography.IUCrJ2018
29792261Structure-based analysis of CysZ-mediated cellular uptake of sulfate.Elife2018
28573582Contemporary Use of Anomalous Diffraction in Biomolecular Structure Analysis.Methods Mol Biol2017
288762352017 publication guidelines for structural modelling of small-angle scattering data from biomolecules in solution: an update.Acta Crystallogr D Struct Biol2017
28524849Structural basis for conductance through TRIC cation channels.Nat Commun2017
26985324Small-Molecule CD4-Mimics: Structure-Based Optimization of HIV-1 Entry Inhibition.ACS Med Chem Lett2016
27662087Structural Basis for Gating and Activation of RyR1.Cell2016
27687475Structures of the colossal RyR1 calcium release channel.Curr Opin Struct Biol2016
27273628Atomic-level analysis of membrane-protein structure.Nat Struct Mol Biol2016
27563101Structure of the STRA6 receptor for retinol uptake.Science2016
25605907Structural insights into mis-regulation of protein kinase A in human tumors.Proc Natl Acad Sci U S A2015
26432413Crystallographic phasing from weak anomalous signals.Curr Opin Struct Biol2015
26510127Structural basis for phosphatidylinositol-phosphate biosynthesis.Nat Commun2015
26235031Structural and Mechanistic Insights into the Latrophilin3-FLRT3 Complex that Mediates Glutamatergic Synapse Development.Structure2015
25635100Protein structure. Structure and activity of tryptophan-rich TSPO proteins.Science2015
25470061Structure of a mammalian ryanodine receptor.Nature2015
24726017Anomalous diffraction in crystallographic phase evaluation.Q Rev Biophys2014
25489088Preassociated apocalmodulin mediates Ca2+-dependent sensitization of activation and inactivation of TMEM16A/16B Ca2+-gated Cl- channels.Proc Natl Acad Sci U S A2014
25286840Multi-crystal native SAD analysis at 6â¿¿keV.Acta Crystallogr D Biol Crystallogr2014
25324390Structure and selectivity in bestrophin ion channels.Science2014
24995510Crystal structures of apparent saccharide sensors from histidine kinase receptors prevalent in a human gut symbiont.FEBS J2014
24904158Structural basis for a pH-sensitive calcium leak across membranes.Science2014
24502450Structure-based design, synthesis and validation of CD4-mimetic small molecule inhibitors of HIV-1 entry: conversion of a viral entry agonist to an antagonist.Acc Chem Res2014
23250061Evolution of diffraction methods for solving crystal structures.Acta Crystallogr A2013
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Collaborators

Co-authored papers 24
Zuckerman Mind Brain Behaviour Institute
Co-authored papers 10
Technical University of Munich (TUM)
Co-authored papers 10
Columbia University
Co-authored papers 7
Co-authored papers 6
Pathology Advanced Translational Research Unit, Emory University School of Medicine
Co-authored papers 4
Institute for Advanced Study (TUM-IAS), TUM (Technische Universitat Munchen)
Co-authored papers 4
Columbia University
Co-authored papers 4
Howard Hughes Medical Institute, Memorial Sloan Kettering Cancer Center
Co-authored papers 3
Co-authored papers 3
Columbia University
Co-authored papers 3
Co-authored papers 3
The University of Texas MD Anderson Cancer Center
Co-authored papers 3
University of California San Francisco
Co-authored papers 3
University of Basel
Co-authored papers 2
University of Virginia
Co-authored papers 2
Co-authored papers 2
University of California davis
Co-authored papers 2
The State University of New Jersey
Co-authored papers 2
Co-authored papers 2
University of California berkeley
Co-authored papers 2
Harvard University
Co-authored papers 2
King's College London BHF Centre for Research Excellence
Co-authored papers 2
Co-authored papers 2
The University of Sydney
Co-authored papers 2
Herbert Irving Comprehensive Cancer Center, Columbia University
Co-authored papers 2
Columbia University
Co-authored papers 2
Friedman Brain Institute, Icahn School of Medicine at Mount Sinai
Co-authored papers 2
National Cancer Institute, National Institutes of Health
Co-authored papers 2
The State University of New Jersey
Co-authored papers 2