Skip to Main Content

Author Details

Andrew C Kruse
Blavatnik Institute, Harvard Medical School
2008
92
49
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37301887Allosteric activation of cell wall synthesis during bacterial growth.Nat Commun2023
37662341Antibodies Expand the Scope of Angiotensin Receptor Pharmacology.bioRxiv2023
36993395A Spatiotemporal Map of Co-Receptor Signaling Networks Underlying B Cell Activation.bioRxiv2023
37081311The relaxin receptor RXFP1 signals through a mechanism of autoinhibition.Nat Chem Biol2023
37104613Bacterial spore germination receptors are nutrient-gated ion channels.Science2023
36172366Mucosal nanobody IgA as inhalable and affordable prophylactic and therapeutic treatment against SARS-CoV-2 and emerging variants.Front Immunol2022
35733252Metal cofactor stabilization by a partner protein is a widespread strategy employed for amidase activation.Proc Natl Acad Sci U S A2022
35654455The SpoVA membrane complex is required for dipicolinic acid import during sporulation and export during germination.Genes Dev2022
36477674An in silico method to assess antibody fragment polyreactivity.Nat Commun2022
33358695Autoantibodies as Endogenous Modulators of GPCR Signaling.Trends Pharmacol Sci2021
33791693Phospholipidosis is a shared mechanism underlying the in vitro antiviral activity of many repurposed drugs against SARS-CoV-2.bioRxiv2021
33893299Protein design and variant prediction using autoregressive generative models.Nat Commun2021
33531570Anti-CfaE nanobodies provide broad cross-protection against major pathogenic enterotoxigenic Escherichia coli strains, with implications for vaccine design.Sci Rep2021
34880501Structures of the Ï¿<sub>2</sub> receptor enable docking for bioactive ligand discovery.Nature2021
34824238Dormant spores sense amino acids through the B subunits of their germination receptors.Nat Commun2021
34326236Drug-induced phospholipidosis confounds drug repurposing for SARS-CoV-2.Science2021
34168368Rapid generation of potent antibodies by autonomous hypermutation in yeast.Nat Chem Biol2021
33446559Cryo-EM structure of the B cell co-receptor CD19 bound to the tetraspanin CD81.Science2021
32152588Structural coordination of polymerization and crosslinking by a SEDS-bPBP peptidoglycan synthase complex.Nat Microbiol2020
32060122A nanobody targeting the LIN28:let-7 interaction fragment of TUT4 blocks uridylation of let-7.Proc Natl Acad Sci U S A2020
32079768Angiotensin and biased analogs induce structurally distinct active conformations within a GPCR.Science2020
32079767Molecular mechanism of biased signaling in a prototypical G protein-coupled receptor.Science2020
31915248Mapping and engineering the interaction between adiponectin and T-cadherin.J Biol Chem2020
33200136Rapid generation of potent antibodies by autonomous hypermutation in yeast.bioRxiv2020
32832023Virtual Screening for Ligand Discovery at the Ï¿<sub>1</sub> Receptor.ACS Med Chem Lett2020
32753386Synthetic nanobodies as angiotensin receptor blockers.Proc Natl Acad Sci U S A2020
32338599A dynamic interaction between CD19 and the tetraspanin CD81 controls B cell co-receptor trafficking.Elife2020
30639100Distinctive Activation Mechanism for Angiotensin Receptor Revealed by a Synthetic Nanobody.Cell2019
31387763The Molecular Function of Ï¿ Receptors: Past, Present, and Future.Trends Pharmacol Sci2019
30814734Structural basis for KCTD-mediated rapid desensitization of GABA<sub>B</sub> signalling.Nature2019
30894747Structural basis of unidirectional export of lipopolysaccharide to the cell surface.Nature2019
31006530A Forward Chemical Genetic Screen Reveals Gut Microbiota Metabolites That Modulate Host Physiology.Cell2019
30648532Solving a specificity mystery.Elife2019
30692671FtsW is a peptidoglycan polymerase that is functional only in complex with its cognate penicillin-binding protein.Nat Microbiol2019
29590088Structure of the peptidoglycan polymerase RodA resolved by evolutionary coupling analysis.Nature2018
30241610Structural Basis of Smoothened Activation in Hedgehog Signaling.Cell2018
29891673Structure and mutagenic analysis of the lipid II flippase MurJ from <i>Escherichia coli</i>.Proc Natl Acad Sci U S A2018
29804838Structural Basis of Smoothened Activation in Hedgehog Signaling.Cell2018
30100265In Vivo Evidence for ATPase-Dependent DNA Translocation by the Bacillus subtilis SMC Condensin Complex.Mol Cell2018
29907971Loss of specificity variants of WzxC suggest that substrate recognition is coupled with transporter opening in MOP-family flippases.Mol Microbiol2018
30403663Evidence that regulation of intramembrane proteolysis is mediated by substrate gating during sporulation in Bacillus subtilis.PLoS Genet2018
30291362Structural basis for Ï¿<sub>1</sub> receptor ligand recognition.Nat Struct Mol Biol2018
30335755A central role for PBP2 in the activation of peptidoglycan polymerization by the bacterial cell elongation machinery.PLoS Genet2018
29581292Sortase ligation enables homogeneous GPCR phosphorylation to reveal diversity in β-arrestin coupling.Proc Natl Acad Sci U S A2018
29498889Structural Basis for G Protein-Coupled Receptor Signaling.Annu Rev Biophys2018
29434346Yeast surface display platform for rapid discovery of conformationally selective nanobodies.Nat Struct Mol Biol2018
29656199Investigating isoindoline, tetrahydroisoquinoline, and tetrahydrobenzazepine scaffolds for their sigma receptor binding properties.Eur J Med Chem2018
29453275Structure-based discovery of selective positive allosteric modulators of antagonists for the M<sub>2</sub> muscarinic acetylcholine receptor.Proc Natl Acad Sci U S A2018
27995388Structural Insights into Sigma1 Function.Handb Exp Pharmacol2017
28388415Multidimensional Tracking of GPCR Signaling via Peroxidase-Catalyzed Proximity Labeling.Cell2017
  • 1 - 50 of 92

Recommended Authors

Michael J Robertson
Stanford University School of Medicine
Career Start Year 2015
Number of shared co-authors 8
Timothy S Strutzenberg
Salk Institute for Biological Studies
Career Start Year 2014
Number of shared co-authors 1
Kate L White
Lawrence Berkeley National Laboratory
Career Start Year 2012
Number of shared co-authors 4
Kuglae Kim
University of North Carolina School of Medicine
Career Start Year 2011
Number of shared co-authors 8
Joel Karpiak
Department of Pharmaceutical Sciences, University of California San Francisco
Career Start Year 2009
Number of shared co-authors 4
Qi Chen
Lilly Research Laboratories
Career Start Year 2006
Number of shared co-authors 0
Suwen Zhao
ShanghaiTech University, China iHuman Institute
Career Start Year 2006
Number of shared co-authors 5
Jens Carlsson
Uppsala University
Career Start Year 2004
Number of shared co-authors 4
Brian E Krumm
University of North Carolina School of Medicine
Career Start Year 2003
Number of shared co-authors 7
Jonathan F Fay
University of North Carolina School of Medicine
Career Start Year 2002
Number of shared co-authors 6
Christopher J Langmead
Monash University
Career Start Year 2000
Number of shared co-authors 0
Joseph D Ho
University of California san francisco
Career Start Year 2000
Number of shared co-authors 0
Judith Klein-Seetharaman
School of Molecular Sciences & College of Health Solutions, Arizona State University
Career Start Year 1999
Number of shared co-authors 5
Udupi A Ramagopal
Poornaprajna Institute of Scientific Research (PPISR)
Career Start Year 1998
Number of shared co-authors 0
Peter Kolb
Institut fur Pharmazeutische Chemie, Philipps-Universitat Marburg
Career Start Year 1996
Number of shared co-authors 4
Witek Kwiatkowski
Swiss Federal Institute of Technology
Career Start Year 1996
Number of shared co-authors 1
John G Luz
Beth Israel Deaconess Medical Center and Harvard Medical School
Career Start Year 1994
Number of shared co-authors 2
Gye Won Han
Bridge Institute, University of Southern California
Career Start Year 1991
Number of shared co-authors 3
Elaine C Meng
Department of Pharmaceutical Chemistry, University of California San Francisco
Career Start Year 1990
Number of shared co-authors 0
Raymond C Stevens
iHuman Institute, ShanghaiTech University
Career Start Year 1988
Number of shared co-authors 6
Herman W T van Vlijmen
Leiden Academic Centre for Drug Research (LACDR), Leiden University
Career Start Year 1988
Number of shared co-authors 0
Miriam Eisenstein
Weizmann Institute of Science
Career Start Year 1988
Number of shared co-authors 3
Steven C Almo
Albert Einstein College of Medicine
Career Start Year 1988
Number of shared co-authors 6
Patrick R Griffin
The Scripps Research Institute
Career Start Year 1987
Number of shared co-authors 3
Senyon Choe
Joint Center for Biosciences
Career Start Year 1986
Number of shared co-authors 1
Antonio Macchiarulo
Department of Pharmaceutical Sciences, University of Perugia
Career Start Year 1986
Number of shared co-authors 0
Lawrence Shapiro
Zuckerman Mind Brain Behaviour Institute
Career Start Year 1982
Number of shared co-authors 0
Ruben Abagyan
Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California
Career Start Year 1981
Number of shared co-authors 2
Harel Weinstein
Institute for Computational Biomedicine
Career Start Year 1973
Number of shared co-authors 6
Jens Meiler
Vanderbilt University
Career Start Year 1954
Number of shared co-authors 4

Collaborators

Aashish Manglik
Department of Pharmaceutical Chemistry, University of California San Francisco
Co-authored papers 17
Debora S Marks
Blavatnik Institute, Harvard Medical School
Co-authored papers 11
Assaf Alon
Harvard Medical School
Co-authored papers 7
Robert J Lefkowitz
Co-authored papers 7
Aaron M Ring
Yale University School of Medicine
Co-authored papers 6
Brian K Shoichet
Department of Pharmaceutical Chemistry, University of California san francisco
Co-authored papers 5
Piotr Sliz
The Manton Center for Orphan Disease Research, Boston Children's Hospital
Co-authored papers 3
Matthew J O'Meara
University of Michigan ann arbor
Co-authored papers 3
Jiankun Lyu
Department of Pharmaceutical Chemistry, University of California san francisco
Co-authored papers 3
Tia A Tummino
Quantitative Biosciences Institute (QBI), University of California San Francisco
Co-authored papers 3
Monir Ejemel
Co-authored papers 2
Adolfo Garc??a-Sastre
Icahn School of Medicine at Mount Sinai
Co-authored papers 2
Heiko S Schadt
Novartis Institutes for BioMedical Research, Novartis Pharma AG
Co-authored papers 2
Youngchang Kim
Argonne National Laboratory
Co-authored papers 2
David A Bernlohr
University of Minnesota-Twin Cities
Co-authored papers 2
James S Fraser
University of California san francisco
Co-authored papers 2
Thomas Vallet
Institut Pasteur, Center for the Viral Populations and Pathogenesis
Co-authored papers 2
Yang Wang
Co-authored papers 2
Steven P Gygi
Harvard Medical School
Co-authored papers 2
Blandine Monel
Institut Pasteur, CNRS UMR 3569
Co-authored papers 2
Francois Pognan
Novartis
Co-authored papers 2
Laszlo Urban
Matrahaza University and Teaching Hospital
Co-authored papers 2
Brian G Pierce
University of Maryland Institute for Bioscience and Biotechnology Research
Co-authored papers 2
Kevan M Shokat
University of California San Francisco
Co-authored papers 2
Marco Vignuzzi
Quantitative Biosciences Institute (QBI) Coronavirus Research Group (QCRG)
Co-authored papers 2
Kris M White
Quantitative Biosciences Institute (QBI) Coronavirus Research Group (QCRG)
Co-authored papers 2
Audrey Fischer
Department of Preclinical Safety, Novartis Institutes for BioMedical Research
Co-authored papers 2
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 2
Georgios Skiniotis
Stanford University School of Medicine
Co-authored papers 2
Carl-Mikael Suomivuori
Stanford University School of Medicine
Co-authored papers 2
Release 1.2