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Author Details

William E Evans
Departments of Oncology. St. Jude Children's Research Hospital
1977
503
114
PMIDPaper TitleJournal TitlePublished Year
37408475Genomic analysis of venous thrombosis in children with acute lymphoblastic leukemia from diverse ancestries.Haematologica2024
36821823<i>DPYD</i> Testing: Time to Put Patient Safety First.J Clin Oncol2023
37503171Germline Genetic <i>NBN</i> Variation and Predisposition to B-cell Acute Lymphoblastic Leukemia in Children.Res Sq2023
37575398Ex vivo Drug Sensitivity Imaging-based Platform for Primary Acute Lymphoblastic Leukemia Cells.Bio Protoc2023
37575398Ex vivo Drug Sensitivity Imaging-based Platform for Primary Acute Lymphoblastic Leukemia Cells.Bio Protoc2023
37729596Prognostic and Pharmacotypic Heterogeneity of Hyperdiploidy in Childhood ALL.J Clin Oncol2023
37729596Prognostic and Pharmacotypic Heterogeneity of Hyperdiploidy in Childhood ALL.J Clin Oncol2023
37019972Etiology of oncogenic fusions in 5,190 childhood cancers and its clinical and therapeutic implication.Nat Commun2023
37347545Targeting a xenobiotic transporter to ameliorate vincristine-induced sensory neuropathy.JCI Insight2023
36604538Pharmacotypes across the genomic landscape of pediatric acute lymphoblastic leukemia and impact on treatment response.Nat Med2023
36865272Bayesian modelling of response to therapy and drug-sensitivity in acute lymphoblastic leukemia.Res Sq2023
36596605<i>PACSIN2</i> as a modulator of autophagy and mercaptopurine cytotoxicity: mechanisms in lymphoid and intestinal cells.Life Sci Alliance2023
35221708<i>CASP</i>orter: A Novel Inducible Human CASP1/NALP3/ASC Inflammasome Biosensor.J Inflamm Res2022
35442732Simultaneous monitoring of disease and microbe dynamics through plasma DNA sequencing in pediatric patients with acute lymphoblastic leukemia.Sci Adv2022
35538648Molybdenum Cofactor Catabolism Unravels the Physiological Role of the Drug Metabolizing Enzyme Thiopurine S-Methyltransferase.Clin Pharmacol Ther2022
35671062Amino acid stress response genes promote L-asparaginase resistance in pediatric acute lymphoblastic leukemia.Blood Adv2022
35575404Molecular Mechanisms of ARID5B-Mediated Genetic Susceptibility to Acute Lymphoblastic Leukemia.J Natl Cancer Inst2022
36028659Epigenomic profiling of glucocorticoid responses identifies cis-regulatory disruptions impacting steroid resistance in childhood acute lymphoblastic leukemia.Leukemia2022
36028659Epigenomic profiling of glucocorticoid responses identifies cis-regulatory disruptions impacting steroid resistance in childhood acute lymphoblastic leukemia.Leukemia2022
35884569Genetic Polymorphisms Associated with Vincristine Pharmacokinetics and Vincristine-Induced Peripheral Neuropathy in Pediatric Oncology Patients.Cancers (Basel)2022
36050548The genomic landscape of pediatric acute lymphoblastic leukemia.Nat Genet2022
36050548The genomic landscape of pediatric acute lymphoblastic leukemia.Nat Genet2022
36251744Clofarabine treatment of KMT2Ar infantile patients with acute lymphoblastic leukemia in St. Jude Total Therapy Study 16.Blood Adv2022
32882024Genome-Wide Association Study of Susceptibility Loci for TCF3-PBX1 Acute Lymphoblastic Leukemia in Children.J Natl Cancer Inst2021
33742760Identification of small molecules that mitigate vincristine-induced neurotoxicity while sensitizing leukemia cells to vincristine.Clin Transl Sci2021
33714976Profiling chromatin accessibility in pediatric acute lymphoblastic leukemia identifies subtype-specific chromatin landscapes and gene regulatory networks.Leukemia2021
33598942Phase 1 study of bendamustine in combination with clofarabine, etoposide, and dexamethasone in pediatric patients with relapsed or refractory hematologic malignancies.Cancer2021
33553612New insights into methotrexate accumulation in leukemia cells <i>in vivo</i>.Mol Cell Oncol2021
34161608Individual prediction of nonadherence to oral mercaptopurine in children with acute lymphoblastic leukemia: Results from COG AALL03N1.Cancer2021
34151288Network-based systems pharmacology reveals heterogeneity in LCK and BCL2 signaling and therapeutic sensitivity of T-cell acute lymphoblastic leukemia.Nat Cancer2021
34151288Network-based systems pharmacology reveals heterogeneity in LCK and BCL2 signaling and therapeutic sensitivity of T-cell acute lymphoblastic leukemia.Nat Cancer2021
34170389Pharmacodynamics of cerebrospinal fluid asparagine after asparaginase.Cancer Chemother Pharmacol2021
34166225Germline RUNX1 variation and predisposition to childhood acute lymphoblastic leukemia.J Clin Invest2021
34047180Improving the treatment of childhood acute lymphoblastic leukemia by optimizing the use of 70-year-old drugs.Haematologica2021
33124053Effects of NT5C2 Germline Variants on 6-Mecaptopurine Metabolism in Children With Acute Lymphoblastic Leukemia.Clin Pharmacol Ther2021
33124053Effects of NT5C2 Germline Variants on 6-Mecaptopurine Metabolism in Children With Acute Lymphoblastic Leukemia.Clin Pharmacol Ther2021
33382913Hypomethylation of NLRP3 gene promoter discriminates glucocorticoid-resistant from glucocorticoid-sensitive idiopathic nephrotic syndrome patients.Clin Transl Sci2021
31563145The Promise and the Reality of Genomics to Guide Precision Medicine in Pediatric Oncology: The Decade Ahead.Clin Pharmacol Ther2020
33164984Pharmacogenomics of intracellular methotrexate polyglutamates in patients' leukemia cells in vivo.J Clin Invest2020
32776229miR-331-3p is involved in glucocorticoid resistance reversion by rapamycin through suppression of the MAPK signaling pathway.Cancer Chemother Pharmacol2020
32635465Population Pharmacokinetics of Vincristine Related to Infusion Duration and Peripheral Neuropathy in Pediatric Oncology Patients.Cancers (Basel)2020
32710497Fluoroquinolone prophylaxis does not increase risk of neuropathy in children with acute lymphoblastic leukemia.Cancer Med2020
32793890Mutational landscape and patterns of clonal evolution in relapsed pediatric acute lymphoblastic leukemia.Blood Cancer Discov2020
32793890Mutational landscape and patterns of clonal evolution in relapsed pediatric acute lymphoblastic leukemia.Blood Cancer Discov2020
32750103Dosing-related saturation of toxicity and accelerated drug clearance with pegaspargase treatment.Blood2020
32750103Dosing-related saturation of toxicity and accelerated drug clearance with pegaspargase treatment.Blood2020
32472969Whole-joint magnetic resonance imaging to assess osteonecrosis in pediatric patients with acute lymphoblastic lymphoma.Pediatr Blood Cancer2020
32207157Incidence of hip and knee osteonecrosis and their associations with bone mineral density in children with acute lymphoblastic leukaemia.Br J Haematol2020
32323890Higher plasma asparaginase activity after intramuscular than intravenous Erwinia asparaginase.Pediatr Blood Cancer2020
31612640Asparaginase formulation impacts hypertriglyceridemia during therapy for acute lymphoblastic leukemia.Pediatr Blood Cancer2020
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Collaborators

Mary V Relling
Departments of Pharmaceutical Sciences.
Co-authored papers 237
Ching-Hon Pui
St. Jude Children's Research Hospital
Co-authored papers 207
Cheng Cheng
St. Jude Children's Research Hospital
Co-authored papers 86
Sima Jeha
St. Jude Children's Research Hospital
Co-authored papers 52
Kristine R Crews
St. Jude Children's Research Hospital
Co-authored papers 41
Charles G Mullighan
St Jude Children's Research Hospital
Co-authored papers 36
Stephen P Hunger
Children's Hospital of Philadelphia
Co-authored papers 36
Mignon L Loh
University of Washington
Co-authored papers 32
Meenakshi Devidas
St Jude Children's Research Hospital
Co-authored papers 32
Scott C Howard
College of Nursing
Co-authored papers 21
Howard L McLeod
Center for Precision Medicine and Functional Genomics, Utah Tech University
Co-authored papers 21
Melissa M Hudson
St Jude Children's Research Hospital
Co-authored papers 17
Kathryn G Roberts
St Jude Children's Research Hospital
Co-authored papers 16
Jinghui Zhang
Changhai Hospital, Second Military Medical University
Co-authored papers 15
Stanley Pounds
St. Jude Children's Research Hospital.
Co-authored papers 11
Geoffrey Neale
St. Jude Children's Research Hospital
Co-authored papers 11
Paul L Martin
Duke University Medical Center
Co-authored papers 10
Elaine R Mardis
The Ohio State University
Co-authored papers 10
Julie M Gastier-Foster
Baylor College of Medicine
Co-authored papers 9
Yu Liu
Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital
Co-authored papers 9
Smita Bhatia
Institute for Cancer Outcomes and Survivorship, University of Alabama at Birmingham
Co-authored papers 9
James K Hicks
H. Lee Moffitt Cancer Center and Research Institute
Co-authored papers 9
Amar Gajjar
St. Jude Children's Research Hospital
Co-authored papers 8
Alex Look
Dana-Farber Cancer Institute
Co-authored papers 8
Robert S Fulton
McDonnell Genome Institute, Washington University School of Medicine
Co-authored papers 8
John Easton
St Jude Children's Research Hospital
Co-authored papers 8
Paul Scheet
University of Texas M.D. Anderson Cancer Center
Co-authored papers 8
Ulrich Broeckel
Medical College of Wisconsin
Co-authored papers 8
Xueyuan Cao
University of Chinese Academy of Sciences
Co-authored papers 8
Teri E Klein
Stanford University
Co-authored papers 8
Release 1.2