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Author Details

Tom W Muir
Princeton University
1993
229
73
Emma Lundberg (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37985791Interrogating epigenetic mechanisms with chemically customized chromatin.Nat Rev Genet2024
37036999A genetically encoded photoproximity labeling approach for mapping protein territories.Proc Natl Acad Sci U S A2023
37503273Distinct phases of cellular signaling revealed by time-resolved protein synthesis.bioRxiv2023
37020029Tracking chromatin state changes using nanoscale photo-proximity labelling.Nature2023
37172569SET1 and p300 Act Synergistically, through Coupled Histone Modifications, in Transcriptional Activation by p53.Cell2023
35081309Synthesis of Oriented Hexasomes and Asymmetric Nucleosomes Using a Template Editing Process.J Am Chem Soc2022
35939668Reconstitution of the <i>S. aureus agr</i> quorum sensing pathway reveals a direct role for the integral membrane protease MroQ in pheromone biosynthesis.Proc Natl Acad Sci U S A2022
35985302Oncohistones: Exposing the nuances and vulnerabilities of epigenetic regulation.Mol Cell2022
36194550A Conserved Histidine Residue Drives Extein Dependence in an Enhanced Atypically Split Intein.J Am Chem Soc2022
36256821TGM2-mediated histone transglutamination is dictated by steric accessibility.Proc Natl Acad Sci U S A2022
35233450A Genetically Encoded Approach for Breaking Chromatin Symmetry.ACS Cent Sci2022
33273722Author Correction: The nucleosome acidic patch and H2A ubiquitination underlie mSWI/SNF recruitment in synovial sarcoma.Nat Struct Mol Biol2021
33649601Oncohistone mutations enhance chromatin remodeling and alter cell fates.Nat Chem Biol2021
33526675Histone H3Q5 serotonylation stabilizes H3K4 methylation and potentiates its readout.Proc Natl Acad Sci U S A2021
33856715Engineering of a Peptide α-N-Methyltransferase to Methylate Non-Proteinogenic Amino Acids.Angew Chem Int Ed Engl2021
34709376Chemical biology approaches to study histone interactors.Biochem Soc Trans2021
34437148Chromatin landscape signals differentially dictate the activities of mSWI/SNF family complexes.Science2021
34187895DOT1L complex regulates transcriptional initiation in human erythroleukemic cells.Proc Natl Acad Sci U S A2021
34153213Molecular Epigenetics: Chemical Biology Tools Come of Age.Annu Rev Biochem2021
34319695Janus Bioparticles: Asymmetric Nucleosomes and Their Preparation Using Chemical Biology Approaches.Acc Chem Res2021
34264659Synthesis of ADP-Ribosylated Histones Reveals Site-Specific Impacts on Chromatin Structure and Function.J Am Chem Soc2021
33458734Reactive intermediates for interactome mapping.Chem Soc Rev2021
32424098Live-cell protein engineering with an ultra-short split intein.Proc Natl Acad Sci U S A2020
31837996The Chaperone FACT and Histone H2B Ubiquitination Maintain S. pombe Genome Architecture through Genic and Subtelomeric Functions.Mol Cell2020
31774265Chemoenzymatic Semisynthesis of Proteins.Chem Rev2020
31819269A basic motif anchoring ISWI to nucleosome acidic patch regulates nucleosome spacing.Nat Chem Biol2020
33208532Single-molecule and in silico dissection of the interaction between Polycomb repressive complex 2 and chromatin.Proc Natl Acad Sci U S A2020
32747783The nucleosome acidic patch and H2A ubiquitination underlie mSWI/SNF recruitment in synovial sarcoma.Nat Struct Mol Biol2020
32966787Bisphosphoglycerate Mutase Deficiency Protects against Cerebral Malaria and Severe Malaria-Induced Anemia.Cell Rep2020
32820778Discovery of quorum quenchers targeting the membrane-embedded sensor domain of the <i>Staphylococcus aureus</i> receptor histidine kinase, AgrC.Chem Commun (Camb)2020
32365172H2B ubiquitylation enhances H3K4 methylation activities of human KMT2 family complexes.Nucleic Acids Res2020
32444835Chromatin as a key consumer in the metabolite economy.Nat Chem Biol2020
32472103In situ chromatin interactomics using a chemical bait and trap approach.Nat Chem2020
31104845Identification of a DNA N6-Adenine Methyltransferase Complex and Its Impact on Chromatin Organization.Cell2019
31767855JASPer controls interphase histone H3S10 phosphorylation by chromosomal kinase JIL-1 in Drosophila.Nat Commun2019
31759698Recurrent SMARCB1 Mutations Reveal a Nucleosome Acidic Patch Interaction Site That Potentiates mSWI/SNF Complex Chromatin Remodeling.Cell2019
30153374Nucleic Acid-Barcoding Technologies: Converting DNA Sequencing into a Broad-Spectrum Molecular Counter.Angew Chem Int Ed Engl2019
31272153Single-Particle Dynamic Light Scattering: Shapes of Individual Nanoparticles.Nano Lett2019
31611394PRC2 engages a bivalent H3K27M-H3K27me3 dinucleosome inhibitor.Proc Natl Acad Sci U S A2019
31263208Protein engineering through tandem transamidation.Nat Chem2019
31479253Nucleation and Propagation of Heterochromatin by the Histone Methyltransferase PRC2: Geometric Constraints and Impact of the Regulatory Subunit JARID2.J Am Chem Soc2019
31418547Proximity Induced Splicing Utilizing Caged Split Inteins.J Am Chem Soc2019
30867594Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3.Nature2019
30773482Identification of a Molecular Latch that Regulates Staphylococcal Virulence.Cell Chem Biol2019
31086175PFA ependymoma-associated protein EZHIP inhibits PRC2 activity through a H3 K27M-like mechanism.Nat Commun2019
30967505Histone H3 tail binds a unique sensing pocket in EZH2 to activate the PRC2 methyltransferase.Proc Natl Acad Sci U S A2019
29339483HELLS and CDCA7 comprise a bipartite nucleosome remodeling complex defective in ICF syndrome.Proc Natl Acad Sci U S A2018
30156841An Atypical Mechanism of Split Intein Molecular Recognition and Folding.J Am Chem Soc2018
30013063Acetylation blocks DNA damage-induced chromatin ADP-ribosylation.Nat Chem Biol2018
30325428Crosstalk among Set1 complex subunits involved in H2B ubiquitylation-dependent H3K4 methylation.Nucleic Acids Res2018
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Collaborators

David Cowburn
Albert Einstein College of Medicine
Co-authored papers 17
C David Allis
The Rockefeller University
Co-authored papers 12
Robert G Roeder
the Rockefeller University
Co-authored papers 11
Yael David
Tri-Institutional PhD Program in Chemical Biology
Co-authored papers 7
Gholson J Lyon
NYS Institute for Basic Research in Developmental Disabilities .
Co-authored papers 7
Brian T Chait
The Rockefeller University
Co-authored papers 6
Benjamin A Garcia
University of Pennsylvania
Co-authored papers 6
Matthew D Sekedat
Columbia University
Co-authored papers 5
Seth A Darst
The Rockefeller University
Co-authored papers 4
Sirano Dhe-Paganon
Dana-Farber Cancer Institute
Co-authored papers 3
Michelle Trester-Zedlitz
University of California San Francisco
Co-authored papers 3
David H Perlman
Co-authored papers 3
Neil T Umbreit
University of Washington
Co-authored papers 2
Li Shen
Co-authored papers 2
Jacob D Jaffe
Co-authored papers 2
Joseph A Loo
University of California los angeles
Co-authored papers 2
Nada Jabado
McGill University Health Centre (MUHC), Montreal Children's Hospital (MCH)
Co-authored papers 2
Yingming Zhao
Co-authored papers 2
Wei-Yi Chen
College of Biomedical Engineering, Taiyuan University of Technology
Co-authored papers 2
Sriram Venneti
Co-authored papers 2
John Kuriyan
University of California berkeley
Co-authored papers 2
Kaushik Dutta
Guru Nanak Institute of Dental Sciences and Research
Co-authored papers 2
Jung-Ae Kim
University of Science and Technology
Co-authored papers 2
David Fushman
University of Maryland, College Park
Co-authored papers 2
Joshua D Rabinowitz
Lewis Sigler Institute for Integrative Genomics, Princeton University
Co-authored papers 2
Henrik Molina
Co-authored papers 1
Gary LeRoy
Co-authored papers 1
Ronald C Beavis
University of Manitoba
Co-authored papers 1
Robert Landick
University of Wisconsin-Madison
Co-authored papers 1
Sharon J Pitteri
Stanford University
Co-authored papers 1
Release 1.2